Triplet chemotherapy for malignant pericardial mesothelioma: A case report

Riichiroh Maruyama; Maki Sakai; Tomomi Nakamura; Ryuichi Suemitsu; Tatsuro Okamoto; Hiroshi Wataya; Kenichi Nishiyama; Toshiaki Kamei; Yukito Ichinose

doi:10.1093/jjco/hyl003

Triplet chemotherapy for malignant pericardial mesothelioma: A case report

Riichiroh Maruyama, Maki Sakai, Tomomi Nakamura, Ryuichi Suemitsu, Tatsuro Okamoto, Hiroshi Wataya, Kenichi Nishiyama, Toshiaki Kamei, Yukito Ichinose

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Malignant pericardial mesothelioma (MPM) is a relatively rare neoplasm in Japan, and no standard treatment regimens have been established for this disease. A 47-year-old woman with MPM presenting with cardiac tamponade was treated using four cycles of chemotherapy consisting of cisplatin (CDDP) 40 mg/m², gemcitabine (GEM) 800 mg/m² and vinorelbine (VNR) 20 mg/m² on days 1 and 8 every 4 weeks after pericardial drainage alone. The diagnosis of MPM was confirmed by an immunohistochemical procedure using either positive or negative markers of malignant mesothelioma in addition to conventional cytological examinations using pericardial effusion. The patient experienced no severe non-hematological or hematological toxicities except for grade 3 neutropenia. The patient has returned to her usual activities and has remained well for 24 months after the last chemotherapy without any evidence of disease progression.

Original language	English
Pages (from-to)	245-248
Number of pages	4
Journal	Japanese journal of clinical oncology
Volume	36
Issue number	4
DOIs	https://doi.org/10.1093/jjco/hyl003
Publication status	Published - Apr 2006
Externally published	Yes

All Science Journal Classification (ASJC) codes

Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1093/jjco/hyl003

Cite this

@article{9047bc1caa304753afad1f4bec30da39,

title = "Triplet chemotherapy for malignant pericardial mesothelioma: A case report",

abstract = "Malignant pericardial mesothelioma (MPM) is a relatively rare neoplasm in Japan, and no standard treatment regimens have been established for this disease. A 47-year-old woman with MPM presenting with cardiac tamponade was treated using four cycles of chemotherapy consisting of cisplatin (CDDP) 40 mg/m2, gemcitabine (GEM) 800 mg/m2 and vinorelbine (VNR) 20 mg/m2 on days 1 and 8 every 4 weeks after pericardial drainage alone. The diagnosis of MPM was confirmed by an immunohistochemical procedure using either positive or negative markers of malignant mesothelioma in addition to conventional cytological examinations using pericardial effusion. The patient experienced no severe non-hematological or hematological toxicities except for grade 3 neutropenia. The patient has returned to her usual activities and has remained well for 24 months after the last chemotherapy without any evidence of disease progression.",

author = "Riichiroh Maruyama and Maki Sakai and Tomomi Nakamura and Ryuichi Suemitsu and Tatsuro Okamoto and Hiroshi Wataya and Kenichi Nishiyama and Toshiaki Kamei and Yukito Ichinose",

note = "Funding Information: The authors thank Dr Brian Quinn for critical comments on the manuscript and Yumiko Oshima for reviewing the patient chart. This study was supported in part by a grant-in-aid for cancer research (15–18) from the Ministry of Health and Welfare, Japan.",

year = "2006",

month = apr,

doi = "10.1093/jjco/hyl003",

language = "English",

volume = "36",

pages = "245--248",

journal = "Japanese Journal of Clinical Oncology",

issn = "0368-2811",

publisher = "Oxford University Press",

number = "4",

}

TY - JOUR

T1 - Triplet chemotherapy for malignant pericardial mesothelioma

T2 - A case report

AU - Maruyama, Riichiroh

AU - Sakai, Maki

AU - Nakamura, Tomomi

AU - Suemitsu, Ryuichi

AU - Okamoto, Tatsuro

AU - Wataya, Hiroshi

AU - Nishiyama, Kenichi

AU - Kamei, Toshiaki

AU - Ichinose, Yukito

N1 - Funding Information: The authors thank Dr Brian Quinn for critical comments on the manuscript and Yumiko Oshima for reviewing the patient chart. This study was supported in part by a grant-in-aid for cancer research (15–18) from the Ministry of Health and Welfare, Japan.

PY - 2006/4

Y1 - 2006/4

N2 - Malignant pericardial mesothelioma (MPM) is a relatively rare neoplasm in Japan, and no standard treatment regimens have been established for this disease. A 47-year-old woman with MPM presenting with cardiac tamponade was treated using four cycles of chemotherapy consisting of cisplatin (CDDP) 40 mg/m2, gemcitabine (GEM) 800 mg/m2 and vinorelbine (VNR) 20 mg/m2 on days 1 and 8 every 4 weeks after pericardial drainage alone. The diagnosis of MPM was confirmed by an immunohistochemical procedure using either positive or negative markers of malignant mesothelioma in addition to conventional cytological examinations using pericardial effusion. The patient experienced no severe non-hematological or hematological toxicities except for grade 3 neutropenia. The patient has returned to her usual activities and has remained well for 24 months after the last chemotherapy without any evidence of disease progression.

AB - Malignant pericardial mesothelioma (MPM) is a relatively rare neoplasm in Japan, and no standard treatment regimens have been established for this disease. A 47-year-old woman with MPM presenting with cardiac tamponade was treated using four cycles of chemotherapy consisting of cisplatin (CDDP) 40 mg/m2, gemcitabine (GEM) 800 mg/m2 and vinorelbine (VNR) 20 mg/m2 on days 1 and 8 every 4 weeks after pericardial drainage alone. The diagnosis of MPM was confirmed by an immunohistochemical procedure using either positive or negative markers of malignant mesothelioma in addition to conventional cytological examinations using pericardial effusion. The patient experienced no severe non-hematological or hematological toxicities except for grade 3 neutropenia. The patient has returned to her usual activities and has remained well for 24 months after the last chemotherapy without any evidence of disease progression.

UR - http://www.scopus.com/inward/record.url?scp=33745700678&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33745700678&partnerID=8YFLogxK

U2 - 10.1093/jjco/hyl003

DO - 10.1093/jjco/hyl003

M3 - Article

C2 - 16533802

AN - SCOPUS:33745700678

SN - 0368-2811

VL - 36

SP - 245

EP - 248

JO - Japanese Journal of Clinical Oncology

JF - Japanese Journal of Clinical Oncology

IS - 4

ER -

Triplet chemotherapy for malignant pericardial mesothelioma: A case report

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this