Triterpene saponins from Cyclamen persicum

Ghezala Mihci-Gaidi, David Pertuit, Tomofumi Miyamoto, Jean François Mirjolet, Olivier Duchamp, Anne Claire Mitaine-Offer, Marie Aleth Lacaille-Dubois

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

A new triterpene saponin 3-O-β-D-glucopyranosyl-(1→4)-α-L- arabinopyranosyl-16α-hydroxy-13β,28-epoxy-oleanan-30-al (1), along with four known triterpene glycosides (2-5) were isolated from Cyclamen persicum. Their structures were characterized by a combination of 1D- and 2D-NMR (1H-1H COSY, TOCSY, NOESY, HSQC, and HMBC) and MS spectrocopic data. The cytotoxicity of compounds 2 and 4 was evaluated using two human colon cancer cell lines HT-29 and HCT 116.

Original languageEnglish
Pages (from-to)1023-1025
Number of pages3
JournalNatural product communications
Volume5
Issue number7
DOIs
Publication statusPublished - 2010

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

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