Triterpene saponins from Cyclamen persicum

Ghezala Mihci-Gaidi, David Pertuit, Tomofumi Miyamoto, Jean François Mirjolet, Olivier Duchamp, Anne Claire Mitaine-Offer, Marie Aleth Lacaille-Dubois

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A new triterpene saponin 3-O-β-D-glucopyranosyl-(1→4)-α-L- arabinopyranosyl-16α-hydroxy-13β,28-epoxy-oleanan-30-al (1), along with four known triterpene glycosides (2-5) were isolated from Cyclamen persicum. Their structures were characterized by a combination of 1D- and 2D-NMR (1H-1H COSY, TOCSY, NOESY, HSQC, and HMBC) and MS spectrocopic data. The cytotoxicity of compounds 2 and 4 was evaluated using two human colon cancer cell lines HT-29 and HCT 116.

Original languageEnglish
Pages (from-to)1023-1025
Number of pages3
JournalNatural product communications
Volume5
Issue number7
Publication statusPublished - Sep 22 2010

Fingerprint

Cyclamen
Cyclamen persicum
Triterpenes
triterpenoid saponins
Saponins
colorectal neoplasms
epoxides
triterpenoids
glycosides
cytotoxicity
cell lines
Glycosides
Colonic Neoplasms
Cell Line
neoplasm cells

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

Cite this

Mihci-Gaidi, G., Pertuit, D., Miyamoto, T., Mirjolet, J. F., Duchamp, O., Mitaine-Offer, A. C., & Lacaille-Dubois, M. A. (2010). Triterpene saponins from Cyclamen persicum. Natural product communications, 5(7), 1023-1025.

Triterpene saponins from Cyclamen persicum. / Mihci-Gaidi, Ghezala; Pertuit, David; Miyamoto, Tomofumi; Mirjolet, Jean François; Duchamp, Olivier; Mitaine-Offer, Anne Claire; Lacaille-Dubois, Marie Aleth.

In: Natural product communications, Vol. 5, No. 7, 22.09.2010, p. 1023-1025.

Research output: Contribution to journalArticle

Mihci-Gaidi, G, Pertuit, D, Miyamoto, T, Mirjolet, JF, Duchamp, O, Mitaine-Offer, AC & Lacaille-Dubois, MA 2010, 'Triterpene saponins from Cyclamen persicum', Natural product communications, vol. 5, no. 7, pp. 1023-1025.
Mihci-Gaidi G, Pertuit D, Miyamoto T, Mirjolet JF, Duchamp O, Mitaine-Offer AC et al. Triterpene saponins from Cyclamen persicum. Natural product communications. 2010 Sep 22;5(7):1023-1025.
Mihci-Gaidi, Ghezala ; Pertuit, David ; Miyamoto, Tomofumi ; Mirjolet, Jean François ; Duchamp, Olivier ; Mitaine-Offer, Anne Claire ; Lacaille-Dubois, Marie Aleth. / Triterpene saponins from Cyclamen persicum. In: Natural product communications. 2010 ; Vol. 5, No. 7. pp. 1023-1025.
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