Abstract
Photoperiodically generated triiodothyronin (T3) in the mediobasal hypothalamus (MBH) has critical roles in the photoperiodic response of the gonads in Japanese quail. In a previous study, we demonstrated seasonal morphological changes in the neuro-glial interaction between gonadotrophin-releasing hormone (GnRH) nerve terminals and glial endfeet in the median eminence (ME). However, a direct relationship between photoperiodically generated T3 and seasonal neuro-glial plasticity in the ME remained unclear. In the present study, we examined the effect of T3 implantation into the MBH on the neuro-glial interaction in the ME. T 3 implantation caused testicular growth and reduced encasement of nerve terminals in the external zone of the ME. In contrast, no morphological changes were observed in birds given an excessive dose of T3, which did not cause testicular growth. These results support the hypothesis that thyroid hormone regulates photoperiodic GnRH secretion via neuro-glial plasticity in the ME.
| Original language | English |
|---|---|
| Pages (from-to) | 175-179 |
| Number of pages | 5 |
| Journal | Cell and tissue research |
| Volume | 324 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Apr 1 2006 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Histology
- Cell Biology
Cite this
T3 implantation mimics photoperiodically reduced encasement of nerve terminals by glial processes in the median eminence of Japanese quail. / Yamamura, Takashi; Yasuo, Shinobu; Hirunagi, Kanjun; Ebihara, Shizufumi; Yoshimura, Takashi.
In: Cell and tissue research, Vol. 324, No. 1, 01.04.2006, p. 175-179.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - T3 implantation mimics photoperiodically reduced encasement of nerve terminals by glial processes in the median eminence of Japanese quail
AU - Yamamura, Takashi
AU - Yasuo, Shinobu
AU - Hirunagi, Kanjun
AU - Ebihara, Shizufumi
AU - Yoshimura, Takashi
PY - 2006/4/1
Y1 - 2006/4/1
N2 - Photoperiodically generated triiodothyronin (T3) in the mediobasal hypothalamus (MBH) has critical roles in the photoperiodic response of the gonads in Japanese quail. In a previous study, we demonstrated seasonal morphological changes in the neuro-glial interaction between gonadotrophin-releasing hormone (GnRH) nerve terminals and glial endfeet in the median eminence (ME). However, a direct relationship between photoperiodically generated T3 and seasonal neuro-glial plasticity in the ME remained unclear. In the present study, we examined the effect of T3 implantation into the MBH on the neuro-glial interaction in the ME. T 3 implantation caused testicular growth and reduced encasement of nerve terminals in the external zone of the ME. In contrast, no morphological changes were observed in birds given an excessive dose of T3, which did not cause testicular growth. These results support the hypothesis that thyroid hormone regulates photoperiodic GnRH secretion via neuro-glial plasticity in the ME.
AB - Photoperiodically generated triiodothyronin (T3) in the mediobasal hypothalamus (MBH) has critical roles in the photoperiodic response of the gonads in Japanese quail. In a previous study, we demonstrated seasonal morphological changes in the neuro-glial interaction between gonadotrophin-releasing hormone (GnRH) nerve terminals and glial endfeet in the median eminence (ME). However, a direct relationship between photoperiodically generated T3 and seasonal neuro-glial plasticity in the ME remained unclear. In the present study, we examined the effect of T3 implantation into the MBH on the neuro-glial interaction in the ME. T 3 implantation caused testicular growth and reduced encasement of nerve terminals in the external zone of the ME. In contrast, no morphological changes were observed in birds given an excessive dose of T3, which did not cause testicular growth. These results support the hypothesis that thyroid hormone regulates photoperiodic GnRH secretion via neuro-glial plasticity in the ME.
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UR - http://www.scopus.com/inward/citedby.url?scp=33644622833&partnerID=8YFLogxK
U2 - 10.1007/s00441-005-0126-8
DO - 10.1007/s00441-005-0126-8
M3 - Article
C2 - 16432711
AN - SCOPUS:33644622833
VL - 324
SP - 175
EP - 179
JO - Cell and Tissue Research
JF - Cell and Tissue Research
SN - 0302-766X
IS - 1
ER -