Two Cases of Advanced Gastric Cancer in the Upper Portion of the Stomach with Laparoscopic Total Gastrectomy after Neoadjuvant Chemotherapy

Kazuki Odagiri, Yasuhiro Miyazaki, Shuji Takiguchi, Tomoki Makino, Tsuyoshi Takahashi, Yukinori Kurokawa, Makoto Yamasaki, Kiyokazu Nakajima, Masaki Mori, Yuichiro Doki

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Abstract

Case 1: A 55-year-old woman was diagnosed with type 3 gastric cancer(U, post, 30 mm, por, cT4aN2M0)of cStage III B. She received 3 courses of a DOS regimen, which consisted of docetaxel, oxaliplatin, and S-1, as neoadjuvant chemotherapy (NAC). She subsequently underwent curative laparoscopic total gastrectomy with D2+No.16a2lat dissection, and resection of part of the right crus of the diaphragm, which was suspected to have cancer infiltration. S-1 was started as adjuvant chemotherapy 37 days after gastrectomy. The patient is alive without recurrence 6 months after surgery. Case 2: A 59-yearold man was diagnosed with type 3 gastric cancer(UM-E, less, 80 mm, por, cT4aN2M0)cStage III B. NACwith DOS was administered. After 3 courses of NACwere completed, we performed spleen-preserving curative laparoscopic total gastrectomy with D2+No.16a2lat dissection. S-1 was started as adjuvant chemotherapy 54 days after gastrectomy. The patient is alive without recurrence 6 months after surgery.

Original languageEnglish
Pages (from-to)1884-1886
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume43
Issue number12
Publication statusPublished - Nov 1 2016
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Odagiri, K., Miyazaki, Y., Takiguchi, S., Makino, T., Takahashi, T., Kurokawa, Y., ... Doki, Y. (2016). Two Cases of Advanced Gastric Cancer in the Upper Portion of the Stomach with Laparoscopic Total Gastrectomy after Neoadjuvant Chemotherapy. Gan to kagaku ryoho. Cancer & chemotherapy, 43(12), 1884-1886.