Two cases of angioimmunoblastic T-cell lymphoma presenting with a skin eruption

Kana Kozono, Kazuhiko Yamamura, Toshihiko Mashino, Masutaka Furue, Hideki Asaoku, Megumu Fujiwara

Research output: Contribution to journalArticle

Abstract

We have experienced two cases of angioimmunoblastic T-cell lymphoma (AITL) presenting with a skin eruption. Patient 1, an 80-year-old woman, had a generalized eruption with faint erythema and some induration. Histopathological examination of the indurated area showed atypical cell infiltration throughout the dermis. Patient 2, a 79-year-old woman, had purpura of the legs. Histopathological examination showed leukocytoclastic vasculitis without atypical cell infiltration. Histopathological examination of the lymph nodes revealed infiltration of atypical lymphocytes and widespread proliferation of the arborizing small vessels, which is a characteristic feature of AITL. About one-half of patients with AITL develop a skin eruption. However, the skin eruption and the histological picture of cutaneous lesions vary considerably. Further accumulation of relevant case studies is required.

Original languageEnglish
Pages (from-to)399-404
Number of pages6
JournalNishinihon Journal of Dermatology
Volume74
Issue number4
DOIs
Publication statusPublished - Dec 27 2012

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T-Cell Lymphoma
Skin
Purpura
Erythema
Dermis
Leg
Lymph Nodes
Lymphocytes

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Two cases of angioimmunoblastic T-cell lymphoma presenting with a skin eruption. / Kozono, Kana; Yamamura, Kazuhiko; Mashino, Toshihiko; Furue, Masutaka; Asaoku, Hideki; Fujiwara, Megumu.

In: Nishinihon Journal of Dermatology, Vol. 74, No. 4, 27.12.2012, p. 399-404.

Research output: Contribution to journalArticle

Kozono, Kana ; Yamamura, Kazuhiko ; Mashino, Toshihiko ; Furue, Masutaka ; Asaoku, Hideki ; Fujiwara, Megumu. / Two cases of angioimmunoblastic T-cell lymphoma presenting with a skin eruption. In: Nishinihon Journal of Dermatology. 2012 ; Vol. 74, No. 4. pp. 399-404.
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