We have experienced two cases of angioimmunoblastic T-cell lymphoma (AITL) presenting with a skin eruption. Patient 1, an 80-year-old woman, had a generalized eruption with faint erythema and some induration. Histopathological examination of the indurated area showed atypical cell infiltration throughout the dermis. Patient 2, a 79-year-old woman, had purpura of the legs. Histopathological examination showed leukocytoclastic vasculitis without atypical cell infiltration. Histopathological examination of the lymph nodes revealed infiltration of atypical lymphocytes and widespread proliferation of the arborizing small vessels, which is a characteristic feature of AITL. About one-half of patients with AITL develop a skin eruption. However, the skin eruption and the histological picture of cutaneous lesions vary considerably. Further accumulation of relevant case studies is required.
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