Two Cases of Hidradenoma Papilliferum

Nahoko Iwasaki-Zeze, Masayoshi Nakao, Eriko Ito, Junichi Motoshita, Satoshi Takeuchi, Masutaka Furue

Research output: Contribution to journalArticle

Abstract

We present two female cases of hidradenoma papilliferum on the vulva. The first case was a 40-year-old woman who recognized a subcutaneous nodule measuring 6 mm on the left of her vulva. The nodule was surgically resected and diagnosed as hidradenoma papilliferum histologically. The second case was a 38-year-old woman with a pink-colored pedunculated tumor measuring 1 cm on the left of her vulva, which often bled because of friction from underwear. The tumor was surgically resected and was also diagnosed as hidradenoma papilliferum histologically. It had previously been thought that hidradenoma papilliferum tumors originate from apocrine sweat glands, but recent studies have suggested that they may be derived from the anogenital mammary-like gland (MLG). The MLG is reported to be immunopositive for both estrogen receptor and progesterone receptor, while the majority of the normal eccrine or apocrine glands are not. Our two cases showed both estrogen receptor and progesterone receptor expression in the columnar cells of the tumor, suggesting that these cases of hidradenoma papilliferum may have been derived from the MLG.

Original languageEnglish
Pages (from-to)209-213
Number of pages5
JournalNishinihon Journal of Dermatology
Volume80
Issue number3
DOIs
Publication statusPublished - Jan 1 2018

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Acrospiroma
Vulva
Human Mammary Glands
Apocrine Glands
Progesterone Receptors
Estrogen Receptors
Neoplasms
Eccrine Glands
Sweat Glands
Friction

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Iwasaki-Zeze, N., Nakao, M., Ito, E., Motoshita, J., Takeuchi, S., & Furue, M. (2018). Two Cases of Hidradenoma Papilliferum. Nishinihon Journal of Dermatology, 80(3), 209-213. https://doi.org/10.2336/nishinihonhifu.80.209

Two Cases of Hidradenoma Papilliferum. / Iwasaki-Zeze, Nahoko; Nakao, Masayoshi; Ito, Eriko; Motoshita, Junichi; Takeuchi, Satoshi; Furue, Masutaka.

In: Nishinihon Journal of Dermatology, Vol. 80, No. 3, 01.01.2018, p. 209-213.

Research output: Contribution to journalArticle

Iwasaki-Zeze, N, Nakao, M, Ito, E, Motoshita, J, Takeuchi, S & Furue, M 2018, 'Two Cases of Hidradenoma Papilliferum', Nishinihon Journal of Dermatology, vol. 80, no. 3, pp. 209-213. https://doi.org/10.2336/nishinihonhifu.80.209
Iwasaki-Zeze N, Nakao M, Ito E, Motoshita J, Takeuchi S, Furue M. Two Cases of Hidradenoma Papilliferum. Nishinihon Journal of Dermatology. 2018 Jan 1;80(3):209-213. https://doi.org/10.2336/nishinihonhifu.80.209
Iwasaki-Zeze, Nahoko ; Nakao, Masayoshi ; Ito, Eriko ; Motoshita, Junichi ; Takeuchi, Satoshi ; Furue, Masutaka. / Two Cases of Hidradenoma Papilliferum. In: Nishinihon Journal of Dermatology. 2018 ; Vol. 80, No. 3. pp. 209-213.
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