Two cases of systemic lupus erythematosus complicated with colonic ulcers

Shoko Miyahara, Satoshi Ito, Atsuko Soeda, Yusuke Chino, Taichi Hayashi, Reiko Takahashi, Daisuke Goto, Isao Matsumoto, Akito Tsutsumi, Takayuki Sumida

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

We report two cases of systemic lupus erythematosus (SLE) complicated with colonic ulcerations. One patient was successfully cured by steroid therapy, while the other did not respond to steroid but oral mesalazine was effective. Systemic lupus erythematosus is frequently accompanied by gastrointestinal symptoms, but colonic lesions are quite rare, and the regular treatment is not fixed yet. The high-dose steroidal regimen may be effective for microvasculitis, although it may increase the risk of perforated ulcer of the intestinal tract, which is a life-threatening complication. Further analysis of its outcomes, and establishment of the regular guideline for its treatment are expected.

Original languageEnglish
Pages (from-to)1298-1306
Number of pages9
JournalInternal Medicine
Volume44
Issue number12
DOIs
Publication statusPublished - Jan 17 2006

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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