Two new acylated tridesmosidic saponins from Astragalus armatus

Nabil Semmar; Tomofumi Miyamoto; Yassine Mrabet; Marie Aleth Lacaille-Dubois

doi:10.1002/hlca.200900303

Two new acylated tridesmosidic saponins from Astragalus armatus

Nabil Semmar, Tomofumi Miyamoto, Yassine Mrabet, Marie Aleth Lacaille-Dubois

Pharmaceutical Health Care and Sciences

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Two new tridesmosidic glycosides of (3β,6α,16β,20R,24S)-20, 24epoxycycloartane-3,6,16,25-tetrol (=cycloastragenol), armatosides I and II (1 and 2, resp.), were isolated from the roots of Astragalus armatus (Fabaceae) as well as the known bidesmosidic glycosides of cycloastragenol, trigonoside II (3) and trojanoside H (4). Their structures were elucidated as (3β,6α, 16β,20R,24S)-3-O-(2,3-di-O-acetyl-β-D-xylopyranosyl)-20, 24-epoxy-25-O-β-D-glucopyranosyl-6-O-β-D-xylopyranosylcycloartane-3,6, 16,25-tetrol (2). These structures were established by extensive NMR and MS analyses and by comparison with literature data.

Original language	English
Pages (from-to)	870-876
Number of pages	7
Journal	Helvetica Chimica Acta
Volume	93
Issue number	5
DOIs	https://doi.org/10.1002/hlca.200900303
Publication status	Published - Jan 1 2010

All Science Journal Classification (ASJC) codes

Catalysis
Biochemistry
Drug Discovery
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.1002/hlca.200900303

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title = "Two new acylated tridesmosidic saponins from Astragalus armatus",

abstract = "Two new tridesmosidic glycosides of (3β,6α,16β,20R,24S)-20, 24epoxycycloartane-3,6,16,25-tetrol (=cycloastragenol), armatosides I and II (1 and 2, resp.), were isolated from the roots of Astragalus armatus (Fabaceae) as well as the known bidesmosidic glycosides of cycloastragenol, trigonoside II (3) and trojanoside H (4). Their structures were elucidated as (3β,6α, 16β,20R,24S)-3-O-(2,3-di-O-acetyl-β-D-xylopyranosyl)-20, 24-epoxy-25-O-β-D-glucopyranosyl-6-O-β-D-xylopyranosylcycloartane-3,6, 16,25-tetrol (2). These structures were established by extensive NMR and MS analyses and by comparison with literature data.",

author = "Nabil Semmar and Tomofumi Miyamoto and Yassine Mrabet and Lacaille-Dubois, {Marie Aleth}",

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doi = "10.1002/hlca.200900303",

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TY - JOUR

T1 - Two new acylated tridesmosidic saponins from Astragalus armatus

AU - Semmar, Nabil

AU - Miyamoto, Tomofumi

AU - Mrabet, Yassine

AU - Lacaille-Dubois, Marie Aleth

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Two new tridesmosidic glycosides of (3β,6α,16β,20R,24S)-20, 24epoxycycloartane-3,6,16,25-tetrol (=cycloastragenol), armatosides I and II (1 and 2, resp.), were isolated from the roots of Astragalus armatus (Fabaceae) as well as the known bidesmosidic glycosides of cycloastragenol, trigonoside II (3) and trojanoside H (4). Their structures were elucidated as (3β,6α, 16β,20R,24S)-3-O-(2,3-di-O-acetyl-β-D-xylopyranosyl)-20, 24-epoxy-25-O-β-D-glucopyranosyl-6-O-β-D-xylopyranosylcycloartane-3,6, 16,25-tetrol (2). These structures were established by extensive NMR and MS analyses and by comparison with literature data.

AB - Two new tridesmosidic glycosides of (3β,6α,16β,20R,24S)-20, 24epoxycycloartane-3,6,16,25-tetrol (=cycloastragenol), armatosides I and II (1 and 2, resp.), were isolated from the roots of Astragalus armatus (Fabaceae) as well as the known bidesmosidic glycosides of cycloastragenol, trigonoside II (3) and trojanoside H (4). Their structures were elucidated as (3β,6α, 16β,20R,24S)-3-O-(2,3-di-O-acetyl-β-D-xylopyranosyl)-20, 24-epoxy-25-O-β-D-glucopyranosyl-6-O-β-D-xylopyranosylcycloartane-3,6, 16,25-tetrol (2). These structures were established by extensive NMR and MS analyses and by comparison with literature data.

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DO - 10.1002/hlca.200900303

M3 - Article

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JF - Helvetica Chimica Acta

IS - 5

ER -

Two new acylated tridesmosidic saponins from Astragalus armatus

Abstract

All Science Journal Classification (ASJC) codes

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