Two new triterpene saponins from Cyclamen africanum Boiss. & Reuter

Soumeya Bencharif-Betina, Tomofumi Miyamoto, Chiaki Tanaka, Zahia Kabouche, Anne Claire Mitaine-Offer, Marie Aleth Lacaille-Dubois

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Two new oleanane-type triterpene saponins, afrocyclamins A and B (1 and 2, resp.), were isolated from a MeOH extract of the roots of Cyclamen africanum Boiss. & Reuter, together with three known triterpenoid saponins, lysikokianoside, deglucocyclamin I, and its dicrotalic acid derivative. The structures were elucidated, on the basis of 1D- and 2D-NMR experiments and mass spectrometry as (3β,20β)-13,28-epoxy-16-oxo-3-{O-β-D- xylopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→4) -O-[β-D-glucopyranosyl-(1→2)]-α-L-arabinopyranosyl}oxy} oleanan-29-al (1) and (3β,16α,20β)-16,28,29-trihydroxy-olean-12- en-3-yl O-4-O-(4-carboxy-3-hydroxy-3-methyl-1-oxobutyl)-β-D-xylopyranosyl- (1→2)-O-β-D-glucopyranosyl-(1→4)-O-[β-D-glucopyranosyl- (1→2)]-α-L-arabinopyranoside (2).

Original languageEnglish
Pages (from-to)1573-1580
Number of pages8
JournalHelvetica Chimica Acta
Volume95
Issue number9
DOIs
Publication statusPublished - Jan 1 2012

Fingerprint

Cyclamen
Triterpenes
Saponins
mass spectroscopy
Oleanolic Acid
nuclear magnetic resonance
acids
spectroscopy
Mass spectrometry
Mass Spectrometry
Nuclear magnetic resonance
Derivatives
Acids
Experiments

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Biochemistry
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Cite this

Bencharif-Betina, S., Miyamoto, T., Tanaka, C., Kabouche, Z., Mitaine-Offer, A. C., & Lacaille-Dubois, M. A. (2012). Two new triterpene saponins from Cyclamen africanum Boiss. & Reuter. Helvetica Chimica Acta, 95(9), 1573-1580. https://doi.org/10.1002/hlca.201200041

Two new triterpene saponins from Cyclamen africanum Boiss. & Reuter. / Bencharif-Betina, Soumeya; Miyamoto, Tomofumi; Tanaka, Chiaki; Kabouche, Zahia; Mitaine-Offer, Anne Claire; Lacaille-Dubois, Marie Aleth.

In: Helvetica Chimica Acta, Vol. 95, No. 9, 01.01.2012, p. 1573-1580.

Research output: Contribution to journalArticle

Bencharif-Betina, S, Miyamoto, T, Tanaka, C, Kabouche, Z, Mitaine-Offer, AC & Lacaille-Dubois, MA 2012, 'Two new triterpene saponins from Cyclamen africanum Boiss. & Reuter', Helvetica Chimica Acta, vol. 95, no. 9, pp. 1573-1580. https://doi.org/10.1002/hlca.201200041
Bencharif-Betina S, Miyamoto T, Tanaka C, Kabouche Z, Mitaine-Offer AC, Lacaille-Dubois MA. Two new triterpene saponins from Cyclamen africanum Boiss. & Reuter. Helvetica Chimica Acta. 2012 Jan 1;95(9):1573-1580. https://doi.org/10.1002/hlca.201200041
Bencharif-Betina, Soumeya ; Miyamoto, Tomofumi ; Tanaka, Chiaki ; Kabouche, Zahia ; Mitaine-Offer, Anne Claire ; Lacaille-Dubois, Marie Aleth. / Two new triterpene saponins from Cyclamen africanum Boiss. & Reuter. In: Helvetica Chimica Acta. 2012 ; Vol. 95, No. 9. pp. 1573-1580.
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