Tyrosinase inhibitory effect of quercetin 4'-O -β- D-glucopyranoside from dried skin of red onion (Allium cepa)

Enos Tangke Arung, Irawan Wijaya Kusuma, Kuniyoshi Shimizu, Ryuichiro Kondo

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

In an effort to find a new whitening agent, we focused our attention on Allium cepa (red onion). Based on biologically guided fractionation using mushroom tyrosinase, quercetin 4'-O -βD-glucopyranoside was isolated from the dried skin of A. cepa. Quercetin 4'-O - βD-glucopyranoside showed tyrosinase inhibitory activity using L-tyrosine or L-DOPA as a substrate, with IC50 values of 4.3 and 52.7μ M, respectively. Based on the results obtained, the dried skin of red onion possesses ingredients with potential for skin-whitening cosmetics with anti-tyrosinase activity.

Original languageEnglish
Pages (from-to)256-263
Number of pages8
JournalNatural Product Research
Volume25
Issue number3
DOIs
Publication statusPublished - Feb 1 2011

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Tyrosinase inhibitory effect of quercetin 4'-O -β- D-glucopyranoside from dried skin of red onion (Allium cepa)'. Together they form a unique fingerprint.

  • Cite this