UCST-type cononsolvency behavior of poly(2-methacryloxyethyl phosphorylcholine) in the mixture of water and ethanol

Yasuhiro Matsuda, Motoyasu Kobayashi, Masahiko Annaka, Kazuhiko Ishihara, Atsushi Takahara

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

A study was conducted for turbimetry and dynamic light scattering (DLS) measurements of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) in the mixture of water and ethanol. PMPC has positive and negative charge in its phosphorylcholine group. PMPC never shrinks in aqueous solution with low ionic strength and network of water molecular formed by hydrogen bonds remain unchanged. PMPC is used for medical materials for its high hydrophilic properties and high biocompatibility. PMPC was synthesized by atom transfer radial polymerization from the corresponding monomer. The size exclusion chromatography (SEC) was used to determine the molecular weight of PMPC samples. The study found that with phase separation, water and alcohols can form hydrogen bonds, which decreased the enthalpy of the system and entropy of PMPC decreased by the precipitation.

Original languageEnglish
Pages (from-to)479-483
Number of pages5
JournalPolymer Journal
Volume40
Issue number5
DOIs
Publication statusPublished - Jul 17 2008

All Science Journal Classification (ASJC) codes

  • Polymers and Plastics
  • Materials Chemistry

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