TY - JOUR
T1 - Ulcer disease prophylaxis in koi carp by bath immersion with chicken egg yolk containing anti-Aeromonas salmonicida IgY
AU - Gan, Hongjian
AU - He, Haiwen
AU - Sato, Atsushi
AU - Hatta, Hajime
AU - Nakao, Miki
AU - Somamoto, Tomonori
N1 - Funding Information:
This work was partly supported by MEXT Project for Developing Innovation Systems (Regional Innovation Strategy Support Program “Kyoto Environmental Nanotechnology Cluster 2008–2013”). The authors would like to thank Enago ( www.enago.jp ) for the English language review. The costs of publication were supported, in part, by a Research Grant for Young Investigators of the Faculty of Agriculture, Kyushu University .
Publisher Copyright:
© 2015 Elsevier Ltd.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Ulcer disease, caused by atypical Aeromonas salmonicida, is a serious concern in ornamental koi carp, because it induces skin ulceration, disfiguring ornamental fish and causing economic loses. The present study aimed to establish a novel prophylaxis with chicken egg yolk immunoglobulin, IgY, against ulcer disease and to assess its feasibility in the ornamental fish industry. Addition of egg yolk powder containing anti- A.. salmonicida IgY to rearing water provided significant protection against an A.. salmonicida bath infection, whereas administration of non-specific IgY did not. Consecutive immersion of fish into rearing water containing specific IgY completely prevented ulcer disease resulting from cohabitation infection, indicating that this prophylaxis could prevent infection from such type of contact. Thus, passive immunization induced by immersing fish into aquarium water containing specific IgY is a prospective prophylaxis against diseases caused by pathogens that invade the skin and gills.
AB - Ulcer disease, caused by atypical Aeromonas salmonicida, is a serious concern in ornamental koi carp, because it induces skin ulceration, disfiguring ornamental fish and causing economic loses. The present study aimed to establish a novel prophylaxis with chicken egg yolk immunoglobulin, IgY, against ulcer disease and to assess its feasibility in the ornamental fish industry. Addition of egg yolk powder containing anti- A.. salmonicida IgY to rearing water provided significant protection against an A.. salmonicida bath infection, whereas administration of non-specific IgY did not. Consecutive immersion of fish into rearing water containing specific IgY completely prevented ulcer disease resulting from cohabitation infection, indicating that this prophylaxis could prevent infection from such type of contact. Thus, passive immunization induced by immersing fish into aquarium water containing specific IgY is a prospective prophylaxis against diseases caused by pathogens that invade the skin and gills.
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U2 - 10.1016/j.rvsc.2015.01.016
DO - 10.1016/j.rvsc.2015.01.016
M3 - Article
C2 - 25687817
AN - SCOPUS:84925260154
SN - 0034-5288
VL - 99
SP - 82
EP - 86
JO - Research in Veterinary Science
JF - Research in Veterinary Science
ER -