Ultrafast separation of small biomolecules by three-dimensional nanowire structure

Sakon Rahong, Takao Yasui, Takeshi Yanagida, Masaki Kanai, Kazuki Nagashima, Noritada Kaji, Tomoji Kawai, Yoshinobu Baba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report on fast biomolecules separation using three-dimensional nanowires structure devices. The three-dimensional nanowire structure can be synthesized and embedded in microchannel by Vapor-Liquid-Solid (VLS) technique. We decorate Au catalyst along the nanowires by DC sputtering and growth nanowire as a cycle to prepare the branch of the nanowire structure. This technique allows researchers to control the pore size of the three-dimensional nanowires by increasing the number of growth time. We separated small DNA molecules mixture (50-100 bp) within 35 seconds and proteins mixture (20-66 kDa) within 2.5 seconds under DC electric fields.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages2432-2434
Number of pages3
ISBN (Electronic)9780979806476
Publication statusPublished - Jan 1 2014
Externally publishedYes
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: Oct 26 2014Oct 30 2014

Publication series

Name18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period10/26/1410/30/14

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

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  • Cite this

    Rahong, S., Yasui, T., Yanagida, T., Kanai, M., Nagashima, K., Kaji, N., Kawai, T., & Baba, Y. (2014). Ultrafast separation of small biomolecules by three-dimensional nanowire structure. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 2432-2434). (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014). Chemical and Biological Microsystems Society.