TY - JOUR
T1 - Ultrahigh hardness and biocompatibility of high-entropy alloy TiAlFeCoNi processed by high-pressure torsion
AU - Edalati, Parisa
AU - Floriano, Ricardo
AU - Tang, Yongpeng
AU - Mohammadi, Abbas
AU - Pereira, Karina Danielle
AU - Luchessi, Augusto Ducati
AU - Edalati, Kaveh
N1 - Funding Information:
One of the authors (K.D.P.) would like to thank São Paulo Research Foundation (FAPESP) for a scholarship (No. 2013/23620-4 ). This work is supported in part by a start-up grant from the WPI-I2CNER , Japan, in part by a Grant-in-Aid for Scientific Research on Innovative Areas from the MEXT , Japan (No. 19H05176 ), in part by a grant from the Brazilian Research Funding Agency FAPESP (No. 2018/15968-4 ), and in part by a grant from the Serrapilheira Institute , Brazil (No. Serra-1709-17362 ).
Funding Information:
One of the authors (K.D.P.) would like to thank S?o Paulo Research Foundation (FAPESP) for a scholarship (No. 2013/23620-4). This work is supported in part by a start-up grant from the WPI-I2CNER, Japan, in part by a Grant-in-Aid for Scientific Research on Innovative Areas from the MEXT, Japan (No. 19H05176), in part by a grant from the Brazilian Research Funding Agency FAPESP (No. 2018/15968-4), and in part by a grant from the Serrapilheira Institute, Brazil (No. Serra-1709-17362).
PY - 2020/7
Y1 - 2020/7
N2 - Despite significant studies on mechanical properties of high-entropy alloys (HEAs), there have been limited attempts to examine the biocompatibility of these alloys. In this study, a lattice-softened high-entropy alloy TiAlFeCoNi with ultrahigh hardness (examined by Vickers method), low elastic modulus (examined by nanoindentation) and superior activity for cell proliferation/viability/cytotoxicity (examined by MTT assay) was developed by employing imperial data and thermodynamic calculations. The designated alloy after casting was processed further by high-pressure torsion (HPT) to improve its hardness via the introduction of nanograins, dislocations and order-disorder transformation. The TiAlFeCoNi alloy with the L21-BCC crystal structure exhibited 170–580% higher hardness and 260–1020% better cellular metabolic activity compared to titanium and Ti-6Al-7Nb biomaterials, suggesting the high potential of HEAs for future biomedical applications.
AB - Despite significant studies on mechanical properties of high-entropy alloys (HEAs), there have been limited attempts to examine the biocompatibility of these alloys. In this study, a lattice-softened high-entropy alloy TiAlFeCoNi with ultrahigh hardness (examined by Vickers method), low elastic modulus (examined by nanoindentation) and superior activity for cell proliferation/viability/cytotoxicity (examined by MTT assay) was developed by employing imperial data and thermodynamic calculations. The designated alloy after casting was processed further by high-pressure torsion (HPT) to improve its hardness via the introduction of nanograins, dislocations and order-disorder transformation. The TiAlFeCoNi alloy with the L21-BCC crystal structure exhibited 170–580% higher hardness and 260–1020% better cellular metabolic activity compared to titanium and Ti-6Al-7Nb biomaterials, suggesting the high potential of HEAs for future biomedical applications.
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U2 - 10.1016/j.msec.2020.110908
DO - 10.1016/j.msec.2020.110908
M3 - Article
C2 - 32409062
AN - SCOPUS:85082770183
SN - 0928-4931
VL - 112
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
M1 - 110908
ER -