Ultrastructure of internal limiting membrane in myopic foveoschisis

Hajime Bando, Yasushi Ikuno, Jun Sub Choi, Yasuo Tano, Ichiro Yamanaka, Tatsuro Ishibashi

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

To reveal the pathogenesis of myopic foveoschisis (MF). Clinicopathological report. Internal limiting membranes (ILMs) were collected from ten patients with MF and five patients with idiopathic macular hole (IMH) as a control. Samples were subjected to transmission electron microscopic study. Characteristics of the ILM were compared between the two groups. Collagen fiber and cell debris were identified on the inner surface of ILM in seven eyes (70%) with MF, significantly more (P <. 05) than found in IMH subjects (0%). More fibrous glial cells were likely to be found on the inner surface of ILM. No significant difference in fibroblast-like cell adhesion was observed. Collagen fiber and cellular component are suggested to play an important role in developing MF. ILM peeling may be essential for vitrectomy for MF.

Original languageEnglish
Pages (from-to)197-199
Number of pages3
JournalAmerican Journal of Ophthalmology
Volume139
Issue number1
DOIs
Publication statusPublished - Jan 1 2005

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Membranes
Retinal Perforations
Collagen
Vitrectomy
Cell Adhesion
Neuroglia
Fibroblasts
Electrons

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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Ultrastructure of internal limiting membrane in myopic foveoschisis. / Bando, Hajime; Ikuno, Yasushi; Choi, Jun Sub; Tano, Yasuo; Yamanaka, Ichiro; Ishibashi, Tatsuro.

In: American Journal of Ophthalmology, Vol. 139, No. 1, 01.01.2005, p. 197-199.

Research output: Contribution to journalArticle

Bando, Hajime ; Ikuno, Yasushi ; Choi, Jun Sub ; Tano, Yasuo ; Yamanaka, Ichiro ; Ishibashi, Tatsuro. / Ultrastructure of internal limiting membrane in myopic foveoschisis. In: American Journal of Ophthalmology. 2005 ; Vol. 139, No. 1. pp. 197-199.
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