Three lipid-oligonucleotides (ODN) carrying TEMPO were prepared and formed a micelle with a diameter of ca. 10 nm. The double strand ODN, lipid-polyT inDS, incorporating TEMPO near the core of the micelle showed the largest water-proton relaxivity, r1, value of 2.4 (25 MHz, 0.59 T) and 6.8 mM-1 s-1 (42 MHz, 1.0 T) per TEMPO.
All Science Journal Classification (ASJC) codes
- Chemical Engineering(all)