Unexpectedly large water-proton relaxivity of TEMPO incorporated into micelle-oligonucleotides

Emi Tanimoto, Satoru Karasawa, Shoji Ueki, Nobuhiro Nitta, Ichio Aoki, Noboru Koga

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Three lipid-oligonucleotides (ODN) carrying TEMPO were prepared and formed a micelle with a diameter of ca. 10 nm. The double strand ODN, lipid-polyT inDS, incorporating TEMPO near the core of the micelle showed the largest water-proton relaxivity, r1, value of 2.4 (25 MHz, 0.59 T) and 6.8 mM-1 s-1 (42 MHz, 1.0 T) per TEMPO.

Original languageEnglish
Pages (from-to)3531-3534
Number of pages4
JournalRSC Advances
Volume3
Issue number11
DOIs
Publication statusPublished - Mar 21 2013

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

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  • Cite this

    Tanimoto, E., Karasawa, S., Ueki, S., Nitta, N., Aoki, I., & Koga, N. (2013). Unexpectedly large water-proton relaxivity of TEMPO incorporated into micelle-oligonucleotides. RSC Advances, 3(11), 3531-3534. https://doi.org/10.1039/c3ra22372h