Unexpectedly large water-proton relaxivity of TEMPO incorporated into micelle-oligonucleotides

Emi Tanimoto, Satoru Karasawa, Shoji Ueki, Nobuhiro Nitta, Ichio Aoki, Noboru Koga

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Three lipid-oligonucleotides (ODN) carrying TEMPO were prepared and formed a micelle with a diameter of ca. 10 nm. The double strand ODN, lipid-polyT inDS, incorporating TEMPO near the core of the micelle showed the largest water-proton relaxivity, r1, value of 2.4 (25 MHz, 0.59 T) and 6.8 mM-1 s-1 (42 MHz, 1.0 T) per TEMPO.

Original languageEnglish
Pages (from-to)3531-3534
Number of pages4
JournalRSC Advances
Volume3
Issue number11
DOIs
Publication statusPublished - Mar 21 2013

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Oligonucleotides
Micelles
Lipids
Protons
Water
TEMPO

All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)
  • Chemistry(all)

Cite this

Tanimoto, E., Karasawa, S., Ueki, S., Nitta, N., Aoki, I., & Koga, N. (2013). Unexpectedly large water-proton relaxivity of TEMPO incorporated into micelle-oligonucleotides. RSC Advances, 3(11), 3531-3534. https://doi.org/10.1039/c3ra22372h

Unexpectedly large water-proton relaxivity of TEMPO incorporated into micelle-oligonucleotides. / Tanimoto, Emi; Karasawa, Satoru; Ueki, Shoji; Nitta, Nobuhiro; Aoki, Ichio; Koga, Noboru.

In: RSC Advances, Vol. 3, No. 11, 21.03.2013, p. 3531-3534.

Research output: Contribution to journalArticle

Tanimoto, E, Karasawa, S, Ueki, S, Nitta, N, Aoki, I & Koga, N 2013, 'Unexpectedly large water-proton relaxivity of TEMPO incorporated into micelle-oligonucleotides', RSC Advances, vol. 3, no. 11, pp. 3531-3534. https://doi.org/10.1039/c3ra22372h
Tanimoto, Emi ; Karasawa, Satoru ; Ueki, Shoji ; Nitta, Nobuhiro ; Aoki, Ichio ; Koga, Noboru. / Unexpectedly large water-proton relaxivity of TEMPO incorporated into micelle-oligonucleotides. In: RSC Advances. 2013 ; Vol. 3, No. 11. pp. 3531-3534.
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