Abstract
Exceptionally fast oxidative addition of an aryl chloride (or a deactivated aryl bromide) to the active Pd0 center, which is ligated by sterically demanding phosphanes, occurs during coupling reactions catalyzed by air-stable Pd1 dimers as shown in the scheme. As a result, the reactions of aryl chlorides and bromides with amines and boronic acids at room temperature are complete within a few minutes. 1-Ad = 1-adamantyl.
| Original language | English |
|---|---|
| Pages (from-to) | 4746-4748 |
| Number of pages | 3 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 41 |
| Issue number | 24 |
| DOIs | |
| Publication status | Published - Dec 16 2002 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Catalysis
- Chemistry(all)
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Stambuli, J. P., Kuwano, R., & Hartwig, J. F. (2002). Unparalleled rates for the activation of aryl chlorides and bromides: Coupling with amines and boronic acids in minutes at room temperature. Angewandte Chemie - International Edition, 41(24), 4746-4748. https://doi.org/10.1002/anie.200290036