TY - JOUR
T1 - Usage and development of optically active cyclic 1,2-diols
AU - Suemune, Hiroshi
AU - Aso, Mariko
PY - 2005/8
Y1 - 2005/8
N2 - Optically active diols are one of the useful groups of compounds for asymmetric reaction as a chiral auxiliary or ligand. Among them, cyclic 1,2-diols are characteristic of the restricted conformation. In this review, we wish to report the use of these compounds for the development of asymmetric reactions such as ring transformations based on intramolecular and intermolecular aldol reactions, and carba-spirocyclization, in which cyclic 1,2-diols are added as a chiral source in combination with a Lewis acid. In addition, the synthesis of optically active cyclic diene comp pounds starting from cyclic 1,2-diols is also discussed.
AB - Optically active diols are one of the useful groups of compounds for asymmetric reaction as a chiral auxiliary or ligand. Among them, cyclic 1,2-diols are characteristic of the restricted conformation. In this review, we wish to report the use of these compounds for the development of asymmetric reactions such as ring transformations based on intramolecular and intermolecular aldol reactions, and carba-spirocyclization, in which cyclic 1,2-diols are added as a chiral source in combination with a Lewis acid. In addition, the synthesis of optically active cyclic diene comp pounds starting from cyclic 1,2-diols is also discussed.
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U2 - 10.5059/yukigoseikyokaishi.63.807
DO - 10.5059/yukigoseikyokaishi.63.807
M3 - Article
AN - SCOPUS:26044480892
SN - 0037-9980
VL - 63
SP - 807
EP - 814
JO - Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
JF - Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
IS - 8
ER -