Usefulness of a deep learning system for diagnosing sjögren's syndrome using ultrasonography images

Yoshitaka Kise, Mayumi Shimizu, Haruka Ikeda, Takeshi Fujii, Chiaki Kuwada, Masako Nishiyama, Takuma Funakoshi, Yoshiko Ariji, Hiroshi Fujita, Akitoshi Katsumata, Kazunori Yoshiura, Eiichiro Ariji

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Objectives: We evaluated the diagnostic performance of a deep learning system for the detection of Sjögren's syndrome (SjS) in ultrasonography (US) images, and compared it with the performance of inexperienced radiologists. Methods: 100 patients with a confirmed diagnosis of SjS according to both the Japanese criteria and American-European Consensus Group criteria and 100 non-SjS patients that had a dry mouth and suspected SjS but were definitively diagnosed as non-SjS were enrolled in this study. All the patients underwent US scans of both the parotid glands (PG) and submandibular glands (SMG). The training group consisted of 80 SjS patients and 80 non-SjS patients, whereas the test group consisted of 20 SjS patients and 20 non-SjS patients for deep learning analysis. The performance of the deep learning system for diagnosing SjS from the US images was compared with the diagnoses made by three inexperienced radiologists. Results: The accuracy, sensitivity and specificity of the deep learning system for the PG were 89.5, 90.0 and 89.0%, respectively, and those for the inexperienced radiologists were 76.7, 67.0 and 86.3%, respectively. The deep learning system results for the SMG were 84.0, 81.0 and 87.0%, respectively, and those for the inexperienced radiologists were 72.0, 78.0 and 66.0%, respectively. The AUC for the inexperienced radiologists was significantly different from that of the deep learning system. conclusions: The deep learning system had a high diagnostic ability for SjS. This suggests that deep learning could be used for diagnostic support when interpreting US images.

Original languageEnglish
Article number20190348
JournalDentomaxillofacial Radiology
Issue number3
Publication statusPublished - Jan 1 2020


All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Radiology Nuclear Medicine and imaging
  • Dentistry(all)

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