Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses

Tomohiro Nakayama, Kengo Yoshimitsu, Hiroyuki Irie, Hitoshi Aibe, Tsuyoshi Tajima, Kenji Shinozaki, Akihiro Nishie, Yoshiki Asayama, Daisuke Kakihara, Shuji Matsuura, Hiroshi Honda

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Purpose: To elucidate whether or not the apparent diffusion coefficient (ADC) values calculated from echo-planar diffusion-weighted (EPDW) MR images are useful In the differential diagnosis of retropentoneal masses. Materials and Methods: In 50 patients with known retroperitoneal masses EPDW images were performed with b-factors of 0-1100 seconds/mm2. The final histologic diagnoses of these lesions were as follows 12 malignant lymphomas four other malignant mesenchymal neoplasms, 25 malignant epithelial neoplasms seven benign mesenchymal neoplasms and two nonneoplastic lesions The ADC values obtained for the solid portion of the lesions were used to represent each lesion, and the values of the histologic groups were compared. Results: The respective value of ADC for 12 malignant lymphomas four other mesenchymal neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions were as follows 0.66 ± 0.26, 1.26 ± 0.50, 0.90 ± 0.20, 1.87 ± 0.48, 1.32 ± 0.20 × 10-3 mm2/second The ADC value of the malignant lymphoma was significantly lower than that of the other malignant mesenchymal lesions and was also lower than the ADC of the benign lesions The ADC value of the malignant epithelial neoplasms was lower than that of the benign mesenchymal tumors The ADC values of the malignant and benign lesions were 0.94 ± 0.30 and 1.75 ± 0.49 × 10-3 mm 2/second, respectively, which also demonstrated a significant difference. Conclusion: ADC values calculated from EPDW MR images may provide useful information in the differential diagnosis of retropentoneal masses.

Original languageEnglish
Pages (from-to)735-742
Number of pages8
JournalJournal of Magnetic Resonance Imaging
Volume20
Issue number4
DOIs
Publication statusPublished - Oct 1 2004

Fingerprint

Differential Diagnosis
Lymphoma
Neoplasms
Carcinoma

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses. / Nakayama, Tomohiro; Yoshimitsu, Kengo; Irie, Hiroyuki; Aibe, Hitoshi; Tajima, Tsuyoshi; Shinozaki, Kenji; Nishie, Akihiro; Asayama, Yoshiki; Kakihara, Daisuke; Matsuura, Shuji; Honda, Hiroshi.

In: Journal of Magnetic Resonance Imaging, Vol. 20, No. 4, 01.10.2004, p. 735-742.

Research output: Contribution to journalArticle

Nakayama, Tomohiro ; Yoshimitsu, Kengo ; Irie, Hiroyuki ; Aibe, Hitoshi ; Tajima, Tsuyoshi ; Shinozaki, Kenji ; Nishie, Akihiro ; Asayama, Yoshiki ; Kakihara, Daisuke ; Matsuura, Shuji ; Honda, Hiroshi. / Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses. In: Journal of Magnetic Resonance Imaging. 2004 ; Vol. 20, No. 4. pp. 735-742.
@article{148d1de73ff74295b0b9bd2b65393c2d,
title = "Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses",
abstract = "Purpose: To elucidate whether or not the apparent diffusion coefficient (ADC) values calculated from echo-planar diffusion-weighted (EPDW) MR images are useful In the differential diagnosis of retropentoneal masses. Materials and Methods: In 50 patients with known retroperitoneal masses EPDW images were performed with b-factors of 0-1100 seconds/mm2. The final histologic diagnoses of these lesions were as follows 12 malignant lymphomas four other malignant mesenchymal neoplasms, 25 malignant epithelial neoplasms seven benign mesenchymal neoplasms and two nonneoplastic lesions The ADC values obtained for the solid portion of the lesions were used to represent each lesion, and the values of the histologic groups were compared. Results: The respective value of ADC for 12 malignant lymphomas four other mesenchymal neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions were as follows 0.66 ± 0.26, 1.26 ± 0.50, 0.90 ± 0.20, 1.87 ± 0.48, 1.32 ± 0.20 × 10-3 mm2/second The ADC value of the malignant lymphoma was significantly lower than that of the other malignant mesenchymal lesions and was also lower than the ADC of the benign lesions The ADC value of the malignant epithelial neoplasms was lower than that of the benign mesenchymal tumors The ADC values of the malignant and benign lesions were 0.94 ± 0.30 and 1.75 ± 0.49 × 10-3 mm 2/second, respectively, which also demonstrated a significant difference. Conclusion: ADC values calculated from EPDW MR images may provide useful information in the differential diagnosis of retropentoneal masses.",
author = "Tomohiro Nakayama and Kengo Yoshimitsu and Hiroyuki Irie and Hitoshi Aibe and Tsuyoshi Tajima and Kenji Shinozaki and Akihiro Nishie and Yoshiki Asayama and Daisuke Kakihara and Shuji Matsuura and Hiroshi Honda",
year = "2004",
month = "10",
day = "1",
doi = "10.1002/jmri.20149",
language = "English",
volume = "20",
pages = "735--742",
journal = "Journal of Magnetic Resonance Imaging",
issn = "1053-1807",
publisher = "John Wiley and Sons Inc.",
number = "4",

}

TY - JOUR

T1 - Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses

AU - Nakayama, Tomohiro

AU - Yoshimitsu, Kengo

AU - Irie, Hiroyuki

AU - Aibe, Hitoshi

AU - Tajima, Tsuyoshi

AU - Shinozaki, Kenji

AU - Nishie, Akihiro

AU - Asayama, Yoshiki

AU - Kakihara, Daisuke

AU - Matsuura, Shuji

AU - Honda, Hiroshi

PY - 2004/10/1

Y1 - 2004/10/1

N2 - Purpose: To elucidate whether or not the apparent diffusion coefficient (ADC) values calculated from echo-planar diffusion-weighted (EPDW) MR images are useful In the differential diagnosis of retropentoneal masses. Materials and Methods: In 50 patients with known retroperitoneal masses EPDW images were performed with b-factors of 0-1100 seconds/mm2. The final histologic diagnoses of these lesions were as follows 12 malignant lymphomas four other malignant mesenchymal neoplasms, 25 malignant epithelial neoplasms seven benign mesenchymal neoplasms and two nonneoplastic lesions The ADC values obtained for the solid portion of the lesions were used to represent each lesion, and the values of the histologic groups were compared. Results: The respective value of ADC for 12 malignant lymphomas four other mesenchymal neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions were as follows 0.66 ± 0.26, 1.26 ± 0.50, 0.90 ± 0.20, 1.87 ± 0.48, 1.32 ± 0.20 × 10-3 mm2/second The ADC value of the malignant lymphoma was significantly lower than that of the other malignant mesenchymal lesions and was also lower than the ADC of the benign lesions The ADC value of the malignant epithelial neoplasms was lower than that of the benign mesenchymal tumors The ADC values of the malignant and benign lesions were 0.94 ± 0.30 and 1.75 ± 0.49 × 10-3 mm 2/second, respectively, which also demonstrated a significant difference. Conclusion: ADC values calculated from EPDW MR images may provide useful information in the differential diagnosis of retropentoneal masses.

AB - Purpose: To elucidate whether or not the apparent diffusion coefficient (ADC) values calculated from echo-planar diffusion-weighted (EPDW) MR images are useful In the differential diagnosis of retropentoneal masses. Materials and Methods: In 50 patients with known retroperitoneal masses EPDW images were performed with b-factors of 0-1100 seconds/mm2. The final histologic diagnoses of these lesions were as follows 12 malignant lymphomas four other malignant mesenchymal neoplasms, 25 malignant epithelial neoplasms seven benign mesenchymal neoplasms and two nonneoplastic lesions The ADC values obtained for the solid portion of the lesions were used to represent each lesion, and the values of the histologic groups were compared. Results: The respective value of ADC for 12 malignant lymphomas four other mesenchymal neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions were as follows 0.66 ± 0.26, 1.26 ± 0.50, 0.90 ± 0.20, 1.87 ± 0.48, 1.32 ± 0.20 × 10-3 mm2/second The ADC value of the malignant lymphoma was significantly lower than that of the other malignant mesenchymal lesions and was also lower than the ADC of the benign lesions The ADC value of the malignant epithelial neoplasms was lower than that of the benign mesenchymal tumors The ADC values of the malignant and benign lesions were 0.94 ± 0.30 and 1.75 ± 0.49 × 10-3 mm 2/second, respectively, which also demonstrated a significant difference. Conclusion: ADC values calculated from EPDW MR images may provide useful information in the differential diagnosis of retropentoneal masses.

UR - http://www.scopus.com/inward/record.url?scp=4744375502&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4744375502&partnerID=8YFLogxK

U2 - 10.1002/jmri.20149

DO - 10.1002/jmri.20149

M3 - Article

C2 - 15390151

AN - SCOPUS:4744375502

VL - 20

SP - 735

EP - 742

JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

SN - 1053-1807

IS - 4

ER -