Usefulness of18F-fluorodeoxyglucose positron emission tomography as predictor of distant metastasis in preoperative carbon-ion radiotherapy for pancreatic cancer

Makoto Shinoto, Shigeru Yamada, Kyosan Yoshikawa, Shigeo Yasuda, Yoshiyuki Shioyama, Hiroshi Honda, Tadashi Kamada, Hirohiko Tsujii

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Aim: The purpose of this study was to evaluate the role of FDG-PET regarding the indication of preoperative carbon-ion radiotherapy (CIRT) for pancreatic cancer patients. Patients and Methods: Patients with resectable pancreatic cancer underwent preoperative CIRT. The impact of baseline SUV max on prognosis for patients was assessed by analyzing correlations with distant metastasis-free survival (DMFS) and overall survival (OS). Results: Out of 21 patients, local recurrence was observed in no patient and distant metastasis was found in 13 patients (62%). 1-year DMFS and OS in low-SUV max group were significantly higher than those in high-SUV max group (91% vs. 20% and 91% vs. 56%). SUVmax was significantly correlated with DMFS and OS. Conclusion: Our data indicated a significant correlation between SUVmax and DMFS. FDG-PET might be useful for determining the indication of preoperative short-course CIRT for patients with resectable pancreatic cancer.

Original languageEnglish
Pages (from-to)5579-5584
Number of pages6
JournalAnticancer research
Volume33
Issue number12
Publication statusPublished - Dec 2013

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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