Utilization of a direct sandwich ELISA kit for rapid diagnosis of adenovirus hemorrhagic cystitis in a patient with adult T-cell leukemia

Y. Asano, Y. Tokunaga, Y. Inoue, H. Gondo, T. Miyamoto, Y. Niho

Research output: Contribution to journalArticlepeer-review

Abstract

We report on a case of adenovirus hemorrhagi cystitis that developed in a 49-year-old woman during intensive chemotherapy for adult T-cell leukemia. Although rapid etiologic diagnosis is essential for the effective management of viral hemorrhagic cystitis, the isolation of adenovirus from urine is often too time-cousuming. We detected the adenovirus antigen in the patient's urine using an Adenoclone direct sandwich ELISA kit (Cambridge Bio Science), which is commonly employed for the diagnosis of adenovirus conjunctivitis. Treatment consisted of intravenous vidarabine and bladder irrigation, which resulted in prompt clinical improvement. The Adenoclone kit was useful for the rapid etiologic diagnosis of adenovirus hemmorrhagic cystitis.

Original languageEnglish
Pages (from-to)460-462
Number of pages3
Journal[Rinshō ketsueki] The Japanese journal of clinical hematology
Volume39
Issue number6
Publication statusPublished - Jun 1998

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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