Value of laparoscopic splenectomy as salvage treatment for relapsed thrombocytopenia after partial splenic arterial embolization

Naotaka Hashimoto, Tomohiko Akahoshi, Morimasa Tomikawa, Hirofumi Kawanaka, Kozo Konishi, hideo uehara, Nao Kinjo, Daisuke Korenaga, Kenji Takenaka, Yoshihiko Maehara

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background/Aims: Recently, partial splenic arterial embolization (PSE) has become a supportive intervention for cirrhotic patients with hypersplenism in the administration of interferon therapy. However, relapsed thrombocytopenia is often observed in patients following PSE. This study aimed to report the clinical efficiency of laparoscopic splenectomy as a salvage treatment for relapsed thrombocytopenia following PSE. Methods: From 2005 to 2009, 6 patients with prior PSE treatment underwent laparoscopic splenectomy. We reviewed the surgical method of laparoscopic splenectomy and the peri- and postoperative outcomes. Results: Laparoscopic splenectomy effectively provided sufficient increases in patient platelet counts. In all patients, laparoscopic splenectomy was performed safely with no significant complications despite PSE-associated dense adhesion to the diaphragm and/or retroperitoneal attachments. Conclusion: Laparoscopic splenectomy provides a sufficient increase in patient platelet counts in relapsed thrombocytopenia following PSE. Therefore, laparoscopic splenectomy appears to be a superior supportive therapy for the treatment of thrombocytopenia in cirrhotic patients.

Original languageEnglish
Pages (from-to)515-520
Number of pages6
JournalDigestive surgery
Volume27
Issue number6
DOIs
Publication statusPublished - Jan 1 2011

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Salvage Therapy
Splenectomy
Thrombocytopenia
Platelet Count
Hypersplenism
Therapeutics
Diaphragm
Interferons

All Science Journal Classification (ASJC) codes

  • Surgery
  • Gastroenterology

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Value of laparoscopic splenectomy as salvage treatment for relapsed thrombocytopenia after partial splenic arterial embolization. / Hashimoto, Naotaka; Akahoshi, Tomohiko; Tomikawa, Morimasa; Kawanaka, Hirofumi; Konishi, Kozo; uehara, hideo; Kinjo, Nao; Korenaga, Daisuke; Takenaka, Kenji; Maehara, Yoshihiko.

In: Digestive surgery, Vol. 27, No. 6, 01.01.2011, p. 515-520.

Research output: Contribution to journalArticle

Hashimoto, N, Akahoshi, T, Tomikawa, M, Kawanaka, H, Konishi, K, uehara, H, Kinjo, N, Korenaga, D, Takenaka, K & Maehara, Y 2011, 'Value of laparoscopic splenectomy as salvage treatment for relapsed thrombocytopenia after partial splenic arterial embolization', Digestive surgery, vol. 27, no. 6, pp. 515-520. https://doi.org/10.1159/000320331
Hashimoto, Naotaka ; Akahoshi, Tomohiko ; Tomikawa, Morimasa ; Kawanaka, Hirofumi ; Konishi, Kozo ; uehara, hideo ; Kinjo, Nao ; Korenaga, Daisuke ; Takenaka, Kenji ; Maehara, Yoshihiko. / Value of laparoscopic splenectomy as salvage treatment for relapsed thrombocytopenia after partial splenic arterial embolization. In: Digestive surgery. 2011 ; Vol. 27, No. 6. pp. 515-520.
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AU - Tomikawa, Morimasa

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AU - Konishi, Kozo

AU - uehara, hideo

AU - Kinjo, Nao

AU - Korenaga, Daisuke

AU - Takenaka, Kenji

AU - Maehara, Yoshihiko

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