Ventricular energetics early after surgery for chronic mitral regurgitation: repair versus replacement.

Ken ichi Imasaka, Yuma Motomatsu, Hidetsugu Hori, Takanori Kono, Yoshihisa Tanoue, Eiki Tayama, Yukihiro Tomita

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The study aim was to compare the effects of mitral valve (MV) repair and replacement with partial (posterior leaflet only) chordal preservation on left ventricular (LV) performance in chronic degenerative mitral regurgitation (MR) by assessing ventricular energetics. Contractility (end-systolic elastance), afterload (effective arterial elastance), and ventricular efficiency (ventriculoarterial coupling and the ratio of stroke work to pressure-volume area were determined using transthoracic echocardiography data obtained before and at one month after surgery in 29 patients undergoing MV repair, and in 12 patients undergoing partial chordal-sparing MV replacement. A two-way analysis of variance with repeated measures was used for comparisons among patients who underwent MV surgery (valve repair versus valve replacement). The LV diastolic volume index was decreased significantly in both groups (p<0.0001), whereas the LV systolic volume index did not change significantly (p=0.956). Despite the similar remarkable decrease in ejection fraction (p<0.0001) in both groups, end-systolic elastance remained unchanged (p=0.312). Effective arterial elastance was increased significantly in both groups (p<0.0001). Ventriculoarterial coupling and the ratio of stroke work to pressure-volume area deteriorated similarly in both groups (p<0.0001 and p<0.0001). Compensation of LV geometry after correction of chronic MR preserved ventricular contractility. Furthermore, the results of MV repair were not superior to those of MV replacement with partial chordal preservation in the early postoperative period. This suggested that partial chordal-sparing MV replacement is an effective method for the treatment of chronic MR in selected patients.

Original languageEnglish
Pages (from-to)804-809
Number of pages6
JournalUnknown Journal
Volume22
Issue number6
Publication statusPublished - Jan 1 2013

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Mitral Valve Insufficiency
Mitral Valve
repair
energetics
replacement
Stroke
variance analysis
Pressure
Postoperative Period
geometry
Echocardiography
Analysis of Variance
index

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Imasaka, K. I., Motomatsu, Y., Hori, H., Kono, T., Tanoue, Y., Tayama, E., & Tomita, Y. (2013). Ventricular energetics early after surgery for chronic mitral regurgitation: repair versus replacement. Unknown Journal, 22(6), 804-809.

Ventricular energetics early after surgery for chronic mitral regurgitation : repair versus replacement. / Imasaka, Ken ichi; Motomatsu, Yuma; Hori, Hidetsugu; Kono, Takanori; Tanoue, Yoshihisa; Tayama, Eiki; Tomita, Yukihiro.

In: Unknown Journal, Vol. 22, No. 6, 01.01.2013, p. 804-809.

Research output: Contribution to journalArticle

Imasaka, KI, Motomatsu, Y, Hori, H, Kono, T, Tanoue, Y, Tayama, E & Tomita, Y 2013, 'Ventricular energetics early after surgery for chronic mitral regurgitation: repair versus replacement.', Unknown Journal, vol. 22, no. 6, pp. 804-809.
Imasaka, Ken ichi ; Motomatsu, Yuma ; Hori, Hidetsugu ; Kono, Takanori ; Tanoue, Yoshihisa ; Tayama, Eiki ; Tomita, Yukihiro. / Ventricular energetics early after surgery for chronic mitral regurgitation : repair versus replacement. In: Unknown Journal. 2013 ; Vol. 22, No. 6. pp. 804-809.
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