Ventricular tachycardia without preceding electrocardiogram change after hypertonic mannitol administration: a case report

Akira Gohara; Sumi Okamatsu-Kifuji; Shinjiro Shono; Midoriko Higashi; Ken Yamaura

doi:10.1186/s40981-018-0191-0

Ventricular tachycardia without preceding electrocardiogram change after hypertonic mannitol administration: a case report

Akira Gohara, Sumi Okamatsu-Kifuji, Shinjiro Shono, Midoriko Higashi, Ken Yamaura

Surgery

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: Mannitol is widely used during neurosurgery, but it has a serious complication including lethal arrhythmia due to mannitol-induced hyperkalemia.

CASE PRESENTATION: We report on a 62-year-old man scheduled for the clipping of an unruptured cerebral artery aneurysm. During surgery, approximately 20 min after the end of 200-mL 20% hypertonic mannitol administration, ventricular tachycardia (VT) occurred without preceding electrocardiogram (ECG) change, such as peaked T waves, and VT was recovered to sinus rhythm after chest compression. A potassium concentration after recovery from VT was 6.4 mEq/L, which was normalized by the administration of calcium gluconate, furosemide, and insulin with glucose.

CONCLUSIONS: Physicians must be aware that VT without preceding ECG change can occur after hypertonic mannitol administration.

Original language	English
Pages (from-to)	54
Journal	JA Clinical Reports
Volume	4
Issue number	1
DOIs	https://doi.org/10.1186/s40981-018-0191-0
Publication status	Published - Jul 23 2018

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title = "Ventricular tachycardia without preceding electrocardiogram change after hypertonic mannitol administration: a case report",

abstract = "BACKGROUND: Mannitol is widely used during neurosurgery, but it has a serious complication including lethal arrhythmia due to mannitol-induced hyperkalemia.CASE PRESENTATION: We report on a 62-year-old man scheduled for the clipping of an unruptured cerebral artery aneurysm. During surgery, approximately 20 min after the end of 200-mL 20% hypertonic mannitol administration, ventricular tachycardia (VT) occurred without preceding electrocardiogram (ECG) change, such as peaked T waves, and VT was recovered to sinus rhythm after chest compression. A potassium concentration after recovery from VT was 6.4 mEq/L, which was normalized by the administration of calcium gluconate, furosemide, and insulin with glucose.CONCLUSIONS: Physicians must be aware that VT without preceding ECG change can occur after hypertonic mannitol administration.",

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T1 - Ventricular tachycardia without preceding electrocardiogram change after hypertonic mannitol administration

T2 - a case report

AU - Gohara, Akira

AU - Okamatsu-Kifuji, Sumi

AU - Shono, Shinjiro

AU - Higashi, Midoriko

AU - Yamaura, Ken

PY - 2018/7/23

Y1 - 2018/7/23

N2 - BACKGROUND: Mannitol is widely used during neurosurgery, but it has a serious complication including lethal arrhythmia due to mannitol-induced hyperkalemia.CASE PRESENTATION: We report on a 62-year-old man scheduled for the clipping of an unruptured cerebral artery aneurysm. During surgery, approximately 20 min after the end of 200-mL 20% hypertonic mannitol administration, ventricular tachycardia (VT) occurred without preceding electrocardiogram (ECG) change, such as peaked T waves, and VT was recovered to sinus rhythm after chest compression. A potassium concentration after recovery from VT was 6.4 mEq/L, which was normalized by the administration of calcium gluconate, furosemide, and insulin with glucose.CONCLUSIONS: Physicians must be aware that VT without preceding ECG change can occur after hypertonic mannitol administration.

AB - BACKGROUND: Mannitol is widely used during neurosurgery, but it has a serious complication including lethal arrhythmia due to mannitol-induced hyperkalemia.CASE PRESENTATION: We report on a 62-year-old man scheduled for the clipping of an unruptured cerebral artery aneurysm. During surgery, approximately 20 min after the end of 200-mL 20% hypertonic mannitol administration, ventricular tachycardia (VT) occurred without preceding electrocardiogram (ECG) change, such as peaked T waves, and VT was recovered to sinus rhythm after chest compression. A potassium concentration after recovery from VT was 6.4 mEq/L, which was normalized by the administration of calcium gluconate, furosemide, and insulin with glucose.CONCLUSIONS: Physicians must be aware that VT without preceding ECG change can occur after hypertonic mannitol administration.

U2 - 10.1186/s40981-018-0191-0

DO - 10.1186/s40981-018-0191-0

M3 - Article

C2 - 32026957

SN - 2363-9024

VL - 4

SP - 54

JO - JA Clinical Reports

JF - JA Clinical Reports

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ER -

Ventricular tachycardia without preceding electrocardiogram change after hypertonic mannitol administration: a case report

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