Vergence disorders in patients with spinocerebellar ataxia 3/Machado- Joseph disease: A synoptophore study

Yasumasa Ohyagi, Takeshi Yamada, Akira Okayama, Nobutaka Sakae, Takao Yamasaki, Tomomi Ohshima, Taiji Sakamoto, Naoki Fujii, Jun ichi Kira

Research output: Contribution to journalArticle

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Abstract

Diplopia, a common symptom in spinocerebellar ataxia 3/Machado-Joseph disease (SCA3/MJD) cases, is not always due to asymmetric ophthalmoplegia. We found a Japanese SCA3/MJD family, in which three patients clearly had an impairment of divergence eye movement. We thus quantitatively examined the vergence ranges in eight Japanese SCA3/MJD cases using the synoptophore test. An impairment of the vergence eye movements was found in all patients, and the vergence impairment pattern, but not the ophthalmoplegia pattern, was found to be compatible with the diplopia pattern. The diplopia in SCA3/MJD cases is, therefore, attributed, at least in part, to the impairment of the vergence eye movements. (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)120-123
Number of pages4
JournalJournal of the Neurological Sciences
Volume173
Issue number2
DOIs
Publication statusPublished - Feb 15 2000

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Machado-Joseph Disease
Diplopia
Eye Movements
Ophthalmoplegia

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Vergence disorders in patients with spinocerebellar ataxia 3/Machado- Joseph disease : A synoptophore study. / Ohyagi, Yasumasa; Yamada, Takeshi; Okayama, Akira; Sakae, Nobutaka; Yamasaki, Takao; Ohshima, Tomomi; Sakamoto, Taiji; Fujii, Naoki; Kira, Jun ichi.

In: Journal of the Neurological Sciences, Vol. 173, No. 2, 15.02.2000, p. 120-123.

Research output: Contribution to journalArticle

Ohyagi, Y, Yamada, T, Okayama, A, Sakae, N, Yamasaki, T, Ohshima, T, Sakamoto, T, Fujii, N & Kira, JI 2000, 'Vergence disorders in patients with spinocerebellar ataxia 3/Machado- Joseph disease: A synoptophore study', Journal of the Neurological Sciences, vol. 173, no. 2, pp. 120-123. https://doi.org/10.1016/S0022-510X(99)00309-3
Ohyagi, Yasumasa ; Yamada, Takeshi ; Okayama, Akira ; Sakae, Nobutaka ; Yamasaki, Takao ; Ohshima, Tomomi ; Sakamoto, Taiji ; Fujii, Naoki ; Kira, Jun ichi. / Vergence disorders in patients with spinocerebellar ataxia 3/Machado- Joseph disease : A synoptophore study. In: Journal of the Neurological Sciences. 2000 ; Vol. 173, No. 2. pp. 120-123.
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