Vestibular schwannoma (vs) surgery: Histological considerations and operative results

Tomio Sasaki, Koji Yoshimoto, Suzuki O. Satoshi

Research output: Chapter in Book/Report/Conference proceedingChapter


In vestibular schwannoma (VS) surgery, understanding of the tumor capsules and nerve-tumor interface is very important to achieve extensive tumor removal while preserving facial and cochlear nerve function. We here demonstrate that tumor capsules of VS consist of thin perineurium of the vestibular nerve and remaining vestibular nerve fibers based on our histological examinations. Also, we show our operative concept of “subcapsular” or “subperineurial” dissection to preserve cranial nerve functions. In this procedure, we place the cleavage plane between the tumor capsules and the tumor parenchyma, which enables us to perform nearly total removal of the tumor by tracing this cleavage plane. Finally, we present our surgical outcomes based on this histological consideration, and conclude that we could increase the possibilities of preserving facial and cochlear nerve functions by performing “subcapsular” or “subperineurial” dissection.

Original languageEnglish
Title of host publicationTumors of the Central Nervous System, Volume 7
Subtitle of host publicationMeningiomas and Schwannomas
PublisherSpringer Netherlands
Number of pages10
ISBN (Electronic)9789400728943
ISBN (Print)9789400728936
Publication statusPublished - Jan 1 2012

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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