Visceral fat area target for improving multiple risk factor clustering in patients with impaired glucose tolerance and type 2 diabetes mellitus

We studied examine the visceral fat area(VFA) target for improving multiple risk factor clustering in patients with impaired glucose tolerance and mild type 2 diabetes mellitus who were not taking medication. Risk factors were defined as systolic blood pressure≥140 mmHg and/or diastolic blood pressure≥90 mmHg, total cholesterol≥220 mg/dl, triglyceride≥150 mg/dl, HDL-cholesterol>40 mg/dl, and fasting glucose≥126 mg/dl and/or HOMA-IR≥1.6. One year of diet and exercise therapy was conducted in 2 groups of patients (n = 54) with multiple risk factors. The most appropriate VFA target for reaching zero or a single risk factor was calculated as 120 cm ² by receiver operating characteristic analysis.