Visualization of cerebrospinal fluid dynamics using multi-spin echo acquisition cine imaging (MUSACI)

Tatsuhiro Wada, Chiaki Tokunaga, Osamu Togao, Ryohei Funatsu, Yasuo Yamashita, Kouji Kobayashi, Masami Yoneyama, Hiroshi Honda

Research output: Contribution to journalArticle

Abstract

Purpose: To evaluate the visualization of CSF dynamics using the novel method multi-spin echo acquisition cine imaging (MUSACI). Methods: MUSACI is based on multi-echo volume isotropic turbo spin-echo acquisition (VISTA) with pulse gating. MUSACI images were acquired in 11 healthy volunteers (7 men, 4 women; age range, 24–46 y, mean age, 31.9 ± 5.51 y). We compared the CSF signal intensities (SIs) at multiple values of the effective echo time (TE eff ) at the lateral ventricle, the foramen of Monro, the third ventricle, and the fourth ventricle. We compared the CSF SI changes in MUSACI at multiple TE eff and the mean velocities in phase contrast (PC) at each trigger delay at the foramen of Monro, the third ventricle, and the fourth ventricle. Results: The anterograde CSF motion from the aqueduct to the fourth ventricle, the retrograde motion from the aqueduct to the third ventricle, and the retrograde motion from the foramen of Monro to the lateral ventricle were observed with MUSACI. The CSF SIs at each TE eff in the foramen of Monro, the third ventricle, and the fourth ventricle were significantly lower than that at each TE eff in the lateral ventricle (P < 0.05). The CSF SI in MUSACI changed with the TE eff , and the CSF movements were observed at each trigger delay in PC. Conclusion: MUSACI can provide both high-resolution anatomical detail of the CSF passageways and physiologic information regarding CSF dynamics in a single scan.

Original languageEnglish
Pages (from-to)331-341
Number of pages11
JournalMagnetic Resonance in Medicine
Volume81
Issue number1
DOIs
Publication statusPublished - Jan 2019

Fingerprint

Fourth Ventricle
Cerebral Ventricles
Third Ventricle
Hydrodynamics
Cerebrospinal Fluid
Lateral Ventricles
Healthy Volunteers

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Visualization of cerebrospinal fluid dynamics using multi-spin echo acquisition cine imaging (MUSACI). / Wada, Tatsuhiro; Tokunaga, Chiaki; Togao, Osamu; Funatsu, Ryohei; Yamashita, Yasuo; Kobayashi, Kouji; Yoneyama, Masami; Honda, Hiroshi.

In: Magnetic Resonance in Medicine, Vol. 81, No. 1, 01.2019, p. 331-341.

Research output: Contribution to journalArticle

Wada, T, Tokunaga, C, Togao, O, Funatsu, R, Yamashita, Y, Kobayashi, K, Yoneyama, M & Honda, H 2019, 'Visualization of cerebrospinal fluid dynamics using multi-spin echo acquisition cine imaging (MUSACI)', Magnetic Resonance in Medicine, vol. 81, no. 1, pp. 331-341. https://doi.org/10.1002/mrm.27394
Wada, Tatsuhiro ; Tokunaga, Chiaki ; Togao, Osamu ; Funatsu, Ryohei ; Yamashita, Yasuo ; Kobayashi, Kouji ; Yoneyama, Masami ; Honda, Hiroshi. / Visualization of cerebrospinal fluid dynamics using multi-spin echo acquisition cine imaging (MUSACI). In: Magnetic Resonance in Medicine. 2019 ; Vol. 81, No. 1. pp. 331-341.
@article{89da6f37982d450b87583a6bd5c04b95,
title = "Visualization of cerebrospinal fluid dynamics using multi-spin echo acquisition cine imaging (MUSACI)",
abstract = "Purpose: To evaluate the visualization of CSF dynamics using the novel method multi-spin echo acquisition cine imaging (MUSACI). Methods: MUSACI is based on multi-echo volume isotropic turbo spin-echo acquisition (VISTA) with pulse gating. MUSACI images were acquired in 11 healthy volunteers (7 men, 4 women; age range, 24–46 y, mean age, 31.9 ± 5.51 y). We compared the CSF signal intensities (SIs) at multiple values of the effective echo time (TE eff ) at the lateral ventricle, the foramen of Monro, the third ventricle, and the fourth ventricle. We compared the CSF SI changes in MUSACI at multiple TE eff and the mean velocities in phase contrast (PC) at each trigger delay at the foramen of Monro, the third ventricle, and the fourth ventricle. Results: The anterograde CSF motion from the aqueduct to the fourth ventricle, the retrograde motion from the aqueduct to the third ventricle, and the retrograde motion from the foramen of Monro to the lateral ventricle were observed with MUSACI. The CSF SIs at each TE eff in the foramen of Monro, the third ventricle, and the fourth ventricle were significantly lower than that at each TE eff in the lateral ventricle (P < 0.05). The CSF SI in MUSACI changed with the TE eff , and the CSF movements were observed at each trigger delay in PC. Conclusion: MUSACI can provide both high-resolution anatomical detail of the CSF passageways and physiologic information regarding CSF dynamics in a single scan.",
author = "Tatsuhiro Wada and Chiaki Tokunaga and Osamu Togao and Ryohei Funatsu and Yasuo Yamashita and Kouji Kobayashi and Masami Yoneyama and Hiroshi Honda",
year = "2019",
month = "1",
doi = "10.1002/mrm.27394",
language = "English",
volume = "81",
pages = "331--341",
journal = "Magnetic Resonance in Medicine",
issn = "0740-3194",
publisher = "John Wiley and Sons Inc.",
number = "1",

}

TY - JOUR

T1 - Visualization of cerebrospinal fluid dynamics using multi-spin echo acquisition cine imaging (MUSACI)

AU - Wada, Tatsuhiro

AU - Tokunaga, Chiaki

AU - Togao, Osamu

AU - Funatsu, Ryohei

AU - Yamashita, Yasuo

AU - Kobayashi, Kouji

AU - Yoneyama, Masami

AU - Honda, Hiroshi

PY - 2019/1

Y1 - 2019/1

N2 - Purpose: To evaluate the visualization of CSF dynamics using the novel method multi-spin echo acquisition cine imaging (MUSACI). Methods: MUSACI is based on multi-echo volume isotropic turbo spin-echo acquisition (VISTA) with pulse gating. MUSACI images were acquired in 11 healthy volunteers (7 men, 4 women; age range, 24–46 y, mean age, 31.9 ± 5.51 y). We compared the CSF signal intensities (SIs) at multiple values of the effective echo time (TE eff ) at the lateral ventricle, the foramen of Monro, the third ventricle, and the fourth ventricle. We compared the CSF SI changes in MUSACI at multiple TE eff and the mean velocities in phase contrast (PC) at each trigger delay at the foramen of Monro, the third ventricle, and the fourth ventricle. Results: The anterograde CSF motion from the aqueduct to the fourth ventricle, the retrograde motion from the aqueduct to the third ventricle, and the retrograde motion from the foramen of Monro to the lateral ventricle were observed with MUSACI. The CSF SIs at each TE eff in the foramen of Monro, the third ventricle, and the fourth ventricle were significantly lower than that at each TE eff in the lateral ventricle (P < 0.05). The CSF SI in MUSACI changed with the TE eff , and the CSF movements were observed at each trigger delay in PC. Conclusion: MUSACI can provide both high-resolution anatomical detail of the CSF passageways and physiologic information regarding CSF dynamics in a single scan.

AB - Purpose: To evaluate the visualization of CSF dynamics using the novel method multi-spin echo acquisition cine imaging (MUSACI). Methods: MUSACI is based on multi-echo volume isotropic turbo spin-echo acquisition (VISTA) with pulse gating. MUSACI images were acquired in 11 healthy volunteers (7 men, 4 women; age range, 24–46 y, mean age, 31.9 ± 5.51 y). We compared the CSF signal intensities (SIs) at multiple values of the effective echo time (TE eff ) at the lateral ventricle, the foramen of Monro, the third ventricle, and the fourth ventricle. We compared the CSF SI changes in MUSACI at multiple TE eff and the mean velocities in phase contrast (PC) at each trigger delay at the foramen of Monro, the third ventricle, and the fourth ventricle. Results: The anterograde CSF motion from the aqueduct to the fourth ventricle, the retrograde motion from the aqueduct to the third ventricle, and the retrograde motion from the foramen of Monro to the lateral ventricle were observed with MUSACI. The CSF SIs at each TE eff in the foramen of Monro, the third ventricle, and the fourth ventricle were significantly lower than that at each TE eff in the lateral ventricle (P < 0.05). The CSF SI in MUSACI changed with the TE eff , and the CSF movements were observed at each trigger delay in PC. Conclusion: MUSACI can provide both high-resolution anatomical detail of the CSF passageways and physiologic information regarding CSF dynamics in a single scan.

UR - http://www.scopus.com/inward/record.url?scp=85052910476&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85052910476&partnerID=8YFLogxK

U2 - 10.1002/mrm.27394

DO - 10.1002/mrm.27394

M3 - Article

C2 - 30194785

AN - SCOPUS:85052910476

VL - 81

SP - 331

EP - 341

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

SN - 0740-3194

IS - 1

ER -