Volume properties of decylammonium chloride and micelle-forming local anesthetic mixtures in the micelle

Hitoshi Matsuki, Hiroshi Kamaya, Issaku Ueda, Michio Yamanaka, Shoji Kaneshina

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The densities of aqueous solutions of a decylammonium chloride (DeAC)-dibucame hydrochloride (DC· HCl) nature and a DeAC-tetracaine hydrochloride (TC·HCl) mixture were measured as a function of the total molality and composition of the mixture at 298.15 K under atmospheric pressure. The molar volumes of the mixture in the monomeric and micellar states of both systems were evaluated by applying the thermodynamic equations to the apparent molar volumes obtained from the density data. They varied linearly with composition between the values of pure components. The volume of mixed micelle formation also showed the linear dependence on the composition. These facts indicate that the DeAC and the anesthetic molecules mix ideally in both the monomeric and micellar states from the viewpomt of volume. On the other hand, the micellar composition was calculated from the composition dependence of the critical micelle concentration values. The shape of the phase diagram of micelle formation was slightly distorted cigar-type due to the nonideal interaction between DeAC and the anesthetic molecules in the mixed micelle. Ideal mixing of volume in the micellar state indicates that the nonideal interaction is not so strong that it affects the molar volume of the micelle.

Original languageEnglish
Pages (from-to)4030-4035
Number of pages6
JournalLangmuir
Volume14
Issue number15
Publication statusPublished - Jul 21 1998

Fingerprint

anesthetics
Anesthetics
Micelles
Local Anesthetics
micelles
Density (specific gravity)
chlorides
Chemical analysis
hydrochlorides
Tetracaine
Molecules
Critical micelle concentration
Tobacco Products
Atmospheric pressure
Phase diagrams
decylamine
molecules
Thermodynamics
atmospheric pressure
phase diagrams

All Science Journal Classification (ASJC) codes

  • Colloid and Surface Chemistry
  • Physical and Theoretical Chemistry

Cite this

Matsuki, H., Kamaya, H., Ueda, I., Yamanaka, M., & Kaneshina, S. (1998). Volume properties of decylammonium chloride and micelle-forming local anesthetic mixtures in the micelle. Langmuir, 14(15), 4030-4035.

Volume properties of decylammonium chloride and micelle-forming local anesthetic mixtures in the micelle. / Matsuki, Hitoshi; Kamaya, Hiroshi; Ueda, Issaku; Yamanaka, Michio; Kaneshina, Shoji.

In: Langmuir, Vol. 14, No. 15, 21.07.1998, p. 4030-4035.

Research output: Contribution to journalArticle

Matsuki, H, Kamaya, H, Ueda, I, Yamanaka, M & Kaneshina, S 1998, 'Volume properties of decylammonium chloride and micelle-forming local anesthetic mixtures in the micelle', Langmuir, vol. 14, no. 15, pp. 4030-4035.
Matsuki H, Kamaya H, Ueda I, Yamanaka M, Kaneshina S. Volume properties of decylammonium chloride and micelle-forming local anesthetic mixtures in the micelle. Langmuir. 1998 Jul 21;14(15):4030-4035.
Matsuki, Hitoshi ; Kamaya, Hiroshi ; Ueda, Issaku ; Yamanaka, Michio ; Kaneshina, Shoji. / Volume properties of decylammonium chloride and micelle-forming local anesthetic mixtures in the micelle. In: Langmuir. 1998 ; Vol. 14, No. 15. pp. 4030-4035.
@article{6c6cf4a8775b463b98ec8ada3338ea6a,
title = "Volume properties of decylammonium chloride and micelle-forming local anesthetic mixtures in the micelle",
abstract = "The densities of aqueous solutions of a decylammonium chloride (DeAC)-dibucame hydrochloride (DC· HCl) nature and a DeAC-tetracaine hydrochloride (TC·HCl) mixture were measured as a function of the total molality and composition of the mixture at 298.15 K under atmospheric pressure. The molar volumes of the mixture in the monomeric and micellar states of both systems were evaluated by applying the thermodynamic equations to the apparent molar volumes obtained from the density data. They varied linearly with composition between the values of pure components. The volume of mixed micelle formation also showed the linear dependence on the composition. These facts indicate that the DeAC and the anesthetic molecules mix ideally in both the monomeric and micellar states from the viewpomt of volume. On the other hand, the micellar composition was calculated from the composition dependence of the critical micelle concentration values. The shape of the phase diagram of micelle formation was slightly distorted cigar-type due to the nonideal interaction between DeAC and the anesthetic molecules in the mixed micelle. Ideal mixing of volume in the micellar state indicates that the nonideal interaction is not so strong that it affects the molar volume of the micelle.",
author = "Hitoshi Matsuki and Hiroshi Kamaya and Issaku Ueda and Michio Yamanaka and Shoji Kaneshina",
year = "1998",
month = "7",
day = "21",
language = "English",
volume = "14",
pages = "4030--4035",
journal = "Langmuir",
issn = "0743-7463",
publisher = "American Chemical Society",
number = "15",

}

TY - JOUR

T1 - Volume properties of decylammonium chloride and micelle-forming local anesthetic mixtures in the micelle

AU - Matsuki, Hitoshi

AU - Kamaya, Hiroshi

AU - Ueda, Issaku

AU - Yamanaka, Michio

AU - Kaneshina, Shoji

PY - 1998/7/21

Y1 - 1998/7/21

N2 - The densities of aqueous solutions of a decylammonium chloride (DeAC)-dibucame hydrochloride (DC· HCl) nature and a DeAC-tetracaine hydrochloride (TC·HCl) mixture were measured as a function of the total molality and composition of the mixture at 298.15 K under atmospheric pressure. The molar volumes of the mixture in the monomeric and micellar states of both systems were evaluated by applying the thermodynamic equations to the apparent molar volumes obtained from the density data. They varied linearly with composition between the values of pure components. The volume of mixed micelle formation also showed the linear dependence on the composition. These facts indicate that the DeAC and the anesthetic molecules mix ideally in both the monomeric and micellar states from the viewpomt of volume. On the other hand, the micellar composition was calculated from the composition dependence of the critical micelle concentration values. The shape of the phase diagram of micelle formation was slightly distorted cigar-type due to the nonideal interaction between DeAC and the anesthetic molecules in the mixed micelle. Ideal mixing of volume in the micellar state indicates that the nonideal interaction is not so strong that it affects the molar volume of the micelle.

AB - The densities of aqueous solutions of a decylammonium chloride (DeAC)-dibucame hydrochloride (DC· HCl) nature and a DeAC-tetracaine hydrochloride (TC·HCl) mixture were measured as a function of the total molality and composition of the mixture at 298.15 K under atmospheric pressure. The molar volumes of the mixture in the monomeric and micellar states of both systems were evaluated by applying the thermodynamic equations to the apparent molar volumes obtained from the density data. They varied linearly with composition between the values of pure components. The volume of mixed micelle formation also showed the linear dependence on the composition. These facts indicate that the DeAC and the anesthetic molecules mix ideally in both the monomeric and micellar states from the viewpomt of volume. On the other hand, the micellar composition was calculated from the composition dependence of the critical micelle concentration values. The shape of the phase diagram of micelle formation was slightly distorted cigar-type due to the nonideal interaction between DeAC and the anesthetic molecules in the mixed micelle. Ideal mixing of volume in the micellar state indicates that the nonideal interaction is not so strong that it affects the molar volume of the micelle.

UR - http://www.scopus.com/inward/record.url?scp=0032114586&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032114586&partnerID=8YFLogxK

M3 - Article

VL - 14

SP - 4030

EP - 4035

JO - Langmuir

JF - Langmuir

SN - 0743-7463

IS - 15

ER -