Water and a protic ionic liquid acted as refolding additives for chemically denatured enzymes

Pankaj Attri; P. Venkatesu; Anil Kumar

doi:10.1039/c2ob26001h

Water and a protic ionic liquid acted as refolding additives for chemically denatured enzymes

Pankaj Attri, P. Venkatesu, Anil Kumar

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

In this communication, we present the ability of water and a protic ionic liquid, triethyl ammonium phosphate (TEAP) to act as refolding additives for the urea-induced chemical denaturated state of the two enzymes, α-chymotrypsin and succinylated Con A. We show that the enzymatic activity is regained and in certain circumstances enhanced.

Original language	English
Pages (from-to)	7475-7478
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	10
Issue number	37
DOIs	https://doi.org/10.1039/c2ob26001h
Publication status	Published - Oct 7 2012
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/c2ob26001h

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abstract = "In this communication, we present the ability of water and a protic ionic liquid, triethyl ammonium phosphate (TEAP) to act as refolding additives for the urea-induced chemical denaturated state of the two enzymes, α-chymotrypsin and succinylated Con A. We show that the enzymatic activity is regained and in certain circumstances enhanced.",

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AU - Kumar, Anil

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N2 - In this communication, we present the ability of water and a protic ionic liquid, triethyl ammonium phosphate (TEAP) to act as refolding additives for the urea-induced chemical denaturated state of the two enzymes, α-chymotrypsin and succinylated Con A. We show that the enzymatic activity is regained and in certain circumstances enhanced.

AB - In this communication, we present the ability of water and a protic ionic liquid, triethyl ammonium phosphate (TEAP) to act as refolding additives for the urea-induced chemical denaturated state of the two enzymes, α-chymotrypsin and succinylated Con A. We show that the enzymatic activity is regained and in certain circumstances enhanced.

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JO - Organic and Biomolecular Chemistry

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ER -

Water and a protic ionic liquid acted as refolding additives for chemically denatured enzymes

Abstract

All Science Journal Classification (ASJC) codes

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