Water and a protic ionic liquid acted as refolding additives for chemically denatured enzymes

Pankaj Attri, P. Venkatesu, Anil Kumar

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

In this communication, we present the ability of water and a protic ionic liquid, triethyl ammonium phosphate (TEAP) to act as refolding additives for the urea-induced chemical denaturated state of the two enzymes, α-chymotrypsin and succinylated Con A. We show that the enzymatic activity is regained and in certain circumstances enhanced.

Original languageEnglish
Pages (from-to)7475-7478
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume10
Issue number37
DOIs
Publication statusPublished - Oct 7 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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