TY - JOUR
T1 - Water-proton relaxivity of hyperbranched polymers carrying TEMPO radicals
AU - Hayashi, Hiroyuki
AU - Karasawa, Satoru
AU - Tanaka, Akihiro
AU - Odoi, Keisuke
AU - Chikama, Katsumi
AU - Kuribayashi, Hideto
AU - Koga, Noboru
PY - 2009/3/1
Y1 - 2009/3/1
N2 - High water-soluble hyperbranched poly(styrene) (HPS) polymers carrying stable 2,2,6,6-tetramethylpiperidine-1 -oxyl (TEMPO) radicals, HPS-N-TEMPO, HPS-Im-TEMPO, and HPS-Im-(TEMPO)2, were prepared in ca. 60% introducing yield. HPS-N-TEMPO and HPS-Im-TEMPO were determined to be nearly spherical shapes of the diameter of 2.4 ± 0.6 and 2.2 ± 0.6 nm, respectively, by transmission electron microscope (TEM) images. The values of water-proton relaxivity, r1, at 25 MHz, 0.59 T, and 25°C were 6.0, 5.2, and 14 mM-1 sec-1 for HPS-N-TEMPO, HPS-Im-TEMPO, and HPS-Im-(TEMPO)2, respectively. The spin-lattice relaxation time (T1)-weighted images in phantom were also observed.
AB - High water-soluble hyperbranched poly(styrene) (HPS) polymers carrying stable 2,2,6,6-tetramethylpiperidine-1 -oxyl (TEMPO) radicals, HPS-N-TEMPO, HPS-Im-TEMPO, and HPS-Im-(TEMPO)2, were prepared in ca. 60% introducing yield. HPS-N-TEMPO and HPS-Im-TEMPO were determined to be nearly spherical shapes of the diameter of 2.4 ± 0.6 and 2.2 ± 0.6 nm, respectively, by transmission electron microscope (TEM) images. The values of water-proton relaxivity, r1, at 25 MHz, 0.59 T, and 25°C were 6.0, 5.2, and 14 mM-1 sec-1 for HPS-N-TEMPO, HPS-Im-TEMPO, and HPS-Im-(TEMPO)2, respectively. The spin-lattice relaxation time (T1)-weighted images in phantom were also observed.
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U2 - 10.1002/mrc.2384
DO - 10.1002/mrc.2384
M3 - Article
C2 - 19140106
AN - SCOPUS:61849101487
VL - 47
SP - 201
EP - 204
JO - Magnetic Resonance in Chemistry
JF - Magnetic Resonance in Chemistry
SN - 0749-1581
IS - 3
ER -