Wear behaviour of an artificial cartilage material for hemiarthroplasty

Kazuhiro Nakashima, Yoshinori Sawae, Nobuaki Tsukamoto, Hiromasa Miura, Yukihide Iwamoto, Teruo Murakami

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    1 Citation (Scopus)

    Abstract

    Hemiarthroplasty is applied if one surface of natural cartilage has diseases but another cartilage surface is healthy. Ultra-high molecular weight polyethylene (UHMWPE), metallic and ceramic materials have been used for hemiarthroplasty. Degeneration of cartilage and wear of UHMWPE are problems that occurred in hemiarthroplasty. Mosaicplasty is applied when a part of cartilage has disease. Healthy cartilage specimen for mosaicplasty is taken from other healthy cartilage part. A new material for mosaicplasty is needed to reduce a burden on patients. In this study, artificial cartilage material was investigated as a material for hemiarthroplasty and mosaicplasty. Poly (vinyl alcohol) (PVA) hydrogel was investigated as a artificial cartilage material for hemiarthroplasty and mosaicplasty. PVA hydrogel was rubbed with cartilage tissue taken from porcine femur condyle in saline solution containing protein and hyaluronic acid in vitro. Coexistence of human γ-globulin (HGG) and hyaluronic acid (HA) had effect to reduce wear of natural cartilage and PVA hydrogel. PVA hydrogel was implanted in rabbit knee joint and a possibility of application for mosaicplasty was investigated. Fixation of PVA hydrogel by bone growth was succeeded. No abnormal inflammation and wear were observed after 4 weeks. Therefore a possibility of application of PVA hydrogel for hemiarthroplasty and mosaicplasty was shown.

    Original languageEnglish
    Title of host publication6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech
    Pages1169-1172
    Number of pages4
    DOIs
    Publication statusPublished - 2010
    Event6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech - Singapore, Singapore
    Duration: Aug 1 2010Aug 6 2010

    Publication series

    NameIFMBE Proceedings
    Volume31 IFMBE
    ISSN (Print)1680-0737

    Other

    Other6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech
    Country/TerritorySingapore
    CitySingapore
    Period8/1/108/6/10

    All Science Journal Classification (ASJC) codes

    • Bioengineering
    • Biomedical Engineering

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