TY - GEN
T1 - Wear reduction by functional protein boundary film on Poly(vinyl alcohol) hydrogel
AU - Nakashima, K.
AU - Sawae, Y.
AU - Murakami, T.
PY - 2005
Y1 - 2005
N2 - Poly(vinyl alcohol) (PVA) hydrogel is a candidate material for artificial cartilage of joint prostheses. From previous researches[1-4] it is shown that the wear of PVA hydrogel depends on the concentration of proteins in lubricants. Therefore it is considered that the adsorbed film formation by protein of albumin or γ-globulin influences upon the wear grade of PVA hydrogel. The remaining film of proteins on the glass plate was observed in fluorescence microscope. The adsorption condition of albumin and γ-globulin was different. The adsorbed film with effective reduction of the wear showed cooperative stratification of albumin and γ-globulin, but the condition of increased the wear showed separation of albumin and γ-globulin. Consequently, to reduce the wear of PVA hydrogel, cooperative stratification layers are effective.
AB - Poly(vinyl alcohol) (PVA) hydrogel is a candidate material for artificial cartilage of joint prostheses. From previous researches[1-4] it is shown that the wear of PVA hydrogel depends on the concentration of proteins in lubricants. Therefore it is considered that the adsorbed film formation by protein of albumin or γ-globulin influences upon the wear grade of PVA hydrogel. The remaining film of proteins on the glass plate was observed in fluorescence microscope. The adsorption condition of albumin and γ-globulin was different. The adsorbed film with effective reduction of the wear showed cooperative stratification of albumin and γ-globulin, but the condition of increased the wear showed separation of albumin and γ-globulin. Consequently, to reduce the wear of PVA hydrogel, cooperative stratification layers are effective.
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U2 - 10.1115/wtc2005-63623
DO - 10.1115/wtc2005-63623
M3 - Conference contribution
AN - SCOPUS:33144459791
SN - 0791842029
SN - 9780791842027
T3 - Proceedings of the World Tribology Congress III - 2005
SP - 655
EP - 656
BT - Proceedings of the World Tribology Congress III - 2005
PB - American Society of Mechanical Engineers
T2 - 2005 World Tribology Congress III
Y2 - 12 September 2005 through 16 September 2005
ER -