Well-differentiated adenocarcinoma of the gallbladder with intratumoral cystic components due to abundant mucin production: A mimicker of adenomyomatosis

Kengo Yoshimitsu, Hiroyuki Irie, Hitoshi Aibe, Tsuyoshi Tajima, Akihiro Nishie, Yoshiki Asayama, Kunishige Matake, Kouji Yamaguchi, Shuji Matsuura, Hiroshi Honda

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The prevalence and etiology of the cystic components within gallbladder carcinomas as seen on MR images were evaluated. A retrospective review of MR images was performed for 35 proven gallbladder carcinomas in search of radiologically detectable intratumoral cystic components. The pathologic specimens were meticulously reviewed to determine the etiology. MR images of 31 adenomyomatoses were also reviewed for comparison to clarify the difference in MR features between these two entities. Three cases out of 35 proven gallbladder carcinomas were found to have intratumoral cystic components. They were all well-differentiated adenocarcinomas, and the cystic components consisted of dilated neoplastic glands filled with abundant mucin pool. Adenomyomatosis tended to have more and rounded cystic components (Rokitansky-Aschoff sinuses) lined in a linear fashion and were flat-elevated in shape, smaller in size and had a regular surface, as compared to the three carcinomas. Although rare, radiologists need to be aware that well-differentiated gallbladder carcinoma with mucin production can have cystic components, which may mimic adenomyomatosis. Careful interpretation of MR images may provide useful information in the differentiation of these two entities.

Original languageEnglish
Pages (from-to)229-233
Number of pages5
JournalEuropean Radiology
Volume15
Issue number2
DOIs
Publication statusPublished - Feb 1 2005

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Mucins
Gallbladder
Adenocarcinoma
Carcinoma

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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Well-differentiated adenocarcinoma of the gallbladder with intratumoral cystic components due to abundant mucin production : A mimicker of adenomyomatosis. / Yoshimitsu, Kengo; Irie, Hiroyuki; Aibe, Hitoshi; Tajima, Tsuyoshi; Nishie, Akihiro; Asayama, Yoshiki; Matake, Kunishige; Yamaguchi, Kouji; Matsuura, Shuji; Honda, Hiroshi.

In: European Radiology, Vol. 15, No. 2, 01.02.2005, p. 229-233.

Research output: Contribution to journalArticle

Yoshimitsu, Kengo ; Irie, Hiroyuki ; Aibe, Hitoshi ; Tajima, Tsuyoshi ; Nishie, Akihiro ; Asayama, Yoshiki ; Matake, Kunishige ; Yamaguchi, Kouji ; Matsuura, Shuji ; Honda, Hiroshi. / Well-differentiated adenocarcinoma of the gallbladder with intratumoral cystic components due to abundant mucin production : A mimicker of adenomyomatosis. In: European Radiology. 2005 ; Vol. 15, No. 2. pp. 229-233.
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