Which primary organ is most suitable for performing pulmonary metastasectomy?

Fumihiko Hirai, Ikuhiko Kinoshita, Taichi Matsubara, Naoki Haratake, Yuka Kouzuma, Shinkichi Takamori, Takai Akamine, Gouji Toyokawa, Tetsuzo Tagawa, Mitsuhiro Takenoyama, Yoshihiko Maehara

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background/Aim: The aim of this study was to assess the appropriateness of pulmonary metastasectomy (MT), with a focus on the primary organ. Patients and Methods: The pathological status of the primary organ, outcome of the MT, disease-free interval, and overall survival were assessed. Results: The primary organ was the most significant prognostic factor analyzed, with a relative risk of 4.6 (95% confidence interval: 1.69-12.56, p=0.003). Patients with colorectal carcinoma had a better survival than those with another primary organ (p=0.003). The hazard ratios by primary organ in comparison to colorectal carcinoma were 3.2 for head and neck carcinoma, 3.5 for soft tissue sarcoma, 8.3 for hepatocellular carcinoma, and 8.9 for urinary carcinoma. Conclusion: Colorectal carcinoma is associated with a greater survival benefit than cancer of other primary organs. Colorectal carcinoma cases should be more aggressively considered for MT than other primary organ cases.

Original languageEnglish
Pages (from-to)1041-1045
Number of pages5
JournalAnticancer research
Volume38
Issue number2
DOIs
Publication statusPublished - Feb 2018

Fingerprint

Metastasectomy
Colorectal Neoplasms
Lung
Survival
Carcinoma
Sarcoma
Hepatocellular Carcinoma
Neck
Head
Confidence Intervals
Neoplasms

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Hirai, F., Kinoshita, I., Matsubara, T., Haratake, N., Kouzuma, Y., Takamori, S., ... Maehara, Y. (2018). Which primary organ is most suitable for performing pulmonary metastasectomy? Anticancer research, 38(2), 1041-1045. https://doi.org/10.21873/anticanres.12320

Which primary organ is most suitable for performing pulmonary metastasectomy? / Hirai, Fumihiko; Kinoshita, Ikuhiko; Matsubara, Taichi; Haratake, Naoki; Kouzuma, Yuka; Takamori, Shinkichi; Akamine, Takai; Toyokawa, Gouji; Tagawa, Tetsuzo; Takenoyama, Mitsuhiro; Maehara, Yoshihiko.

In: Anticancer research, Vol. 38, No. 2, 02.2018, p. 1041-1045.

Research output: Contribution to journalArticle

Hirai, F, Kinoshita, I, Matsubara, T, Haratake, N, Kouzuma, Y, Takamori, S, Akamine, T, Toyokawa, G, Tagawa, T, Takenoyama, M & Maehara, Y 2018, 'Which primary organ is most suitable for performing pulmonary metastasectomy?', Anticancer research, vol. 38, no. 2, pp. 1041-1045. https://doi.org/10.21873/anticanres.12320
Hirai F, Kinoshita I, Matsubara T, Haratake N, Kouzuma Y, Takamori S et al. Which primary organ is most suitable for performing pulmonary metastasectomy? Anticancer research. 2018 Feb;38(2):1041-1045. https://doi.org/10.21873/anticanres.12320
Hirai, Fumihiko ; Kinoshita, Ikuhiko ; Matsubara, Taichi ; Haratake, Naoki ; Kouzuma, Yuka ; Takamori, Shinkichi ; Akamine, Takai ; Toyokawa, Gouji ; Tagawa, Tetsuzo ; Takenoyama, Mitsuhiro ; Maehara, Yoshihiko. / Which primary organ is most suitable for performing pulmonary metastasectomy?. In: Anticancer research. 2018 ; Vol. 38, No. 2. pp. 1041-1045.
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