Zirex: A novel zinc-regulated expression system for Lactococcus lactis

Dongdong Mu, Manuel Montalbán-López, Yoshimitsu Masuda, Oscar P. Kuipers

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)


Here, we report a new zinc-inducible expression system for Lactococcus lactis, called Zirex, consisting of the pneumococcal repressor SczA and PczcD. PczcD tightly regulates the expression of green fluorescent protein in L. lactis. We show the applicability of Zirex together with the nisin-controlled expression system, enabling simultaneous but independent regulation of different genes.

Original languageEnglish
Pages (from-to)4503-4508
Number of pages6
JournalApplied and environmental microbiology
Issue number14
Publication statusPublished - Jul 2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology


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