Zn(II) dipicolylamine-based artificial receptor as a new entry for surface recognition of α-helical peptides in aqueous solution

Yasuko Mito-oka, Shinya Tsukiji, Takashi Hiraoka, Noriyuki Kasagi, Seiji Shinkai, Itaru Hamachi

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

It is clear by CD spectral titration that Zn(II)dipicolylamine-based dinuclear complexes selectively bind and stabilize the α-helix conformation of peptides having two histidine (His) residues at specific positions (H-i and i+4 or i+7 or i+11).

Original languageEnglish
Pages (from-to)7059-7062
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number40
DOIs
Publication statusPublished - Oct 1 2001

Fingerprint

Artificial Receptors
Titration
Histidine
Conformations
Peptides
zinc(II) dipicolylamine

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Zn(II) dipicolylamine-based artificial receptor as a new entry for surface recognition of α-helical peptides in aqueous solution. / Mito-oka, Yasuko; Tsukiji, Shinya; Hiraoka, Takashi; Kasagi, Noriyuki; Shinkai, Seiji; Hamachi, Itaru.

In: Tetrahedron Letters, Vol. 42, No. 40, 01.10.2001, p. 7059-7062.

Research output: Contribution to journalArticle

Mito-oka, Yasuko ; Tsukiji, Shinya ; Hiraoka, Takashi ; Kasagi, Noriyuki ; Shinkai, Seiji ; Hamachi, Itaru. / Zn(II) dipicolylamine-based artificial receptor as a new entry for surface recognition of α-helical peptides in aqueous solution. In: Tetrahedron Letters. 2001 ; Vol. 42, No. 40. pp. 7059-7062.
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