研究成果

2020

Accumulated nocturnal hypoxemia predict arterial endothelial function in patients with sleep-disordered breathing with or without chronic heart failure

Sawatari, H., Chishaki, A., Nishizaka, M., Miyazono, M., Tokunou, T., Magota, C., Yamamoto, U., Handa, S. S. & Ando, S. I., 6 1 2020, : : Heart and Vessels. 35, 6, p. 800-807 8 p.

研究成果: Contribution to journalArticle

Altered glycosylation associated with dedifferentiation of hepatocellular carcinoma: A lectin microarray-based study

Takayama, H., Ohta, M., Iwashita, Y., Uchida, H., Shitomi, Y., Yada, K. & Inomata, M., 3 6 2020, : : BMC Cancer. 20, 1, 192.

研究成果: Contribution to journalArticle

公開

A multicenter prospective registration study on laparoscopic pancreatectomy in Japan: report on the assessment of 1,429 patients

Ohtsuka, T., Nagakawa, Y., Toyama, H., Takeda, Y., Maeda, A., Kumamoto, Y., Nakamura, Y., Hashida, K., Honda, G., Fukuzawa, K., Toyoda, E., Tanabe, M., Gotohda, N., Matsumoto, I., Ryu, T., Uyama, I., Kojima, T., Unno, M., Ichikawa, D., Inoue, Y. および40人, Matsukawa, H., Sudo, T., Takaori, K., Yamaue, H., Eguchi, S., Tahara, M., Shinzeki, M., Eguchi, H., Kurata, M., Morimoto, M., Hayashi, H., Marubashi, S., Inomata, M., Kimura, K., Amaya, K., Sho, M., Yoshida, R., Murata, A., Yoshitomi, H., Hakamada, K., Yasunaga, M., Abe, N., Hioki, M., Tsuchiya, M., Misawa, T., Seyama, Y., Noshiro, H., Sakamoto, E., Hasegawa, K., Kawabata, Y., Uchida, Y., Kameyama, S., Ko, S., Takao, T., Kitahara, K., Nakahira, S., Baba, H., Watanabe, M., Yamamoto, M. & Nakamura, M., 2 1 2020, : : Journal of Hepato-Biliary-Pancreatic Sciences. 27, 2, p. 47-55 9 p.

研究成果: Contribution to journalArticle

5 引用 (Scopus)

A novel C1 inhibitor gene mutation in a family with hereditary angioedema: Use of genetic analysis to facilitate early diagnosis

Yokoyama, K., Horiuchi, T., Hashimura, C. & Yoshida, A., 1 2020, : : Allergology International. 69, 1, p. 148-149 2 p.

研究成果: Contribution to journalLetter

公開

Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells

Takeishi, K., Collin de l'Hortet, A., Wang, Y., Handa, K., Guzman-Lepe, J., Matsubara, K., Morita, K., Jang, S., Haep, N., Florentino, R. M., Yuan, F., Fukumitsu, K., Tobita, K., Sun, W., Franks, J., Delgado, E. R., Shapiro, E. M., Fraunhoffer, N. A., Duncan, A. W., Yagi, H. および3人, Mashimo, T., Fox, I. J. & Soto-Gutierrez, A., 6 2 2020, : : Cell Reports. 31, 9, 107711.

研究成果: Contribution to journalArticle

公開
公開

A unified simulation model for understanding the diversity of cancer evolution

Niida, A., Hasegawa, T., Innan, H., Shibata, T., Mimori, K. & Miyano, S., 1 1 2020, : : PeerJ. 2020, 4, 8842.

研究成果: Contribution to journalArticle

公開

BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis

Chen, Q., Lei, J. H., Bao, J., Wang, H., Hao, W., Li, L., Peng, C., Masuda, T., Miao, K., Xu, J., Xu, X. & Deng, C. X., 3 1 2020, : : Advanced Science. 7, 6, 1903616.

研究成果: Contribution to journalArticle

公開

Circulating PD-1 mRNA in Peripheral Blood is a Potential Biomarker for Predicting Survival of Breast Cancer Patients

Noda, M., Masuda, T., Ito, S., Tobo, T., Kitagawa, A., Hu, Q., Shimizu, D., Eguchi, H., Etoh, T., Ohno, S., Inomata, M. & Mimori, K., 2020, (受理済み/印刷中) : : Annals of Surgical Oncology.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

Current status of endoscopic surgery in Japan: The 14th National Survey of Endoscopic Surgery by the Japan Society for Endoscopic Surgery

Inomata, M., Shiroshita, H., Uchida, H., Bandoh, T., Akira, S., Yamaguchi, S., Kurokawa, Y., Seki, Y., Eguchi, S., Wada, N., Takiguchi, S., Ieiri, S., Endo, S., Iwazaki, M., Sato, Y., Tamaki, Y., Kitamura, K., Tabata, M., Kanayama, H., Mimata, H. および8人, Hasegawa, T., Takahashi, H., Onishi, K., Uemura, T., Hashizume, M., Matsumoto, S., Kitano, S. & Watanabe, M., 1 1 2020, : : Asian journal of endoscopic surgery. 13, 1, p. 7-18 12 p.

研究成果: Contribution to journalArticle

公開
6 引用 (Scopus)

Drug repositioning in cancer: The current situation in Japan

Masuda, T., Tsuruda, Y., Matsumoto, Y., Uchida, H., Nakayama, K. I. & Mimori, K., 4 1 2020, : : Cancer Science. 111, 4, p. 1039-1046 8 p.

研究成果: Contribution to journalReview article

公開
1 引用 (Scopus)

Genetic landscape of external auditory canal squamous cell carcinoma

Sato, K., Komune, N., Hongo, T., Koike, K., Niida, A., Uchi, R., Noda, T., Kogo, R., Matsumoto, N., Yamamoto, H., Masuda, M., Oda, Y., Mimori, K. & Nakagawa, T., 2020, (受理済み/印刷中) : : Cancer Science.

研究成果: Contribution to journalArticle

公開

GTF2IRD1 on chromosome 7 is a novel oncogene regulating the tumor-suppressor gene TGFβR2 in colorectal cancer

Nambara, S., Masuda, T., Kobayashi, Y., Sato, K., Tobo, T., Koike, K., Noda, M., Ogawa, Y., Kuroda, Y., Ito, S., Eguchi, H., Sugimachi, K. & Mimori, K., 2 1 2020, : : Cancer Science. 111, 2, p. 343-355 13 p.

研究成果: Contribution to journalArticle

公開

Homeostatic milieu induces production of deoxyribonuclease 1-like 3 from myeloid cells

Inokuchi, S., Mitoma, H., Kawano, S., Nakano, S., Ayano, M., Kimoto, Y., Akahoshi, M., Arinobu, Y., Tsukamoto, H., Akashi, K., Horiuchi, T. & Niiro, H., 4 15 2020, : : Journal of Immunology. 204, 8, p. 2088-2097 10 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

KIF15 Εxpression in Τumor-associated Μonocytes Ιs a prognostic biomarker in hepatocellular carcinoma

Kitagawa, A., Masuda, T., Takahashi, J., Tobo, T., Noda, M., Kuroda, Y., Hu, Q., Kouyama, Y., Kobayashi, Y., Kuramitsu, S., Sato, K., Fujii, A., Yoshikawa, Y., wakiyama, H., Shimizu, D., Tsuruda, Y., Eguchi, H., Doki, Y., Mori, M. & Mimori, K., 1 1 2020, : : Cancer Genomics and Proteomics. 17, 2, p. 141-149 9 p.

研究成果: Contribution to journalArticle

公開

Living-Donor Liver Transplantation for Patients With Extrahepatic Malignancy: A Series of 14 Patients in a Single Institution

Kosai-Fujimoto, Y., Yoshizumi, T., Tomiyama, T., Morinaga, A., Iseda, N., Inokuchi, S., Yugawa, K., Yoshiya, S., Toshima, T., Takeishi, K., Itoh, S., Harada, N., Ikegami, T. & Mori, M., 4 2020, : : Transplantation Proceedings. 52, 3, p. 889-893 5 p.

研究成果: Contribution to journalArticle

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein–Barr virus-associated gastric cancer

Ohmura, H., Ito, M., Uchino, K., Okada, C., Tanishima, S., Yamada, Y., Momosaki, S., Komoda, M., Kuwayama, M., Yamaguchi, K., Okumura, Y., Nakano, M., Tsuchihashi, K., Isobe, T., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., 1 1 2020, : : FEBS Open Bio. 10, 1, p. 147-157 11 p.

研究成果: Contribution to journalArticle

公開
1 引用 (Scopus)

N-cadherin mRNA levels in peripheral blood could be a potential indicator of new metastases in breast cancer: A pilot study

Masuda, T., Ueo, H., Kai, Y., Noda, M., Hu, Q., Sato, K., Fujii, A., Hayashi, N., Tsuruda, Y., Otsu, H., Kuroda, Y., Eguchi, H., Ohno, S., Mimori, K. & Ueo, H., 1 2 2020, : : International journal of molecular sciences. 21, 2, 511.

研究成果: Contribution to journalArticle

公開
1 引用 (Scopus)

OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody

Ohmura, H., Yamaguchi, K., Hanamura, F., Ito, M., Makiyama, A., Uchino, K., Shimokawa, H., Tamura, S., Esaki, T., Mitsugi, K., Shibata, Y., Oda, H., Tsuchihashi, K., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., 5 12 2020, : : British journal of cancer. 122, 10, p. 1507-1517 11 p.

研究成果: Contribution to journalArticle

Pharmacokinetic and toxicodynamic evaluation of 5-fluorouracil administration after major hepatectomy in a rat model

Tada, K., Iwashita, Y., Shiraiwa, K., Uchida, H., Oshima, Y., Sato, Y., Nakanuma, H., Hirashita, T., Masuda, T., Endo, Y., Takeuchi, Y., Ohta, M., Itoh, H. & Inomata, M., 2 1 2020, : : Cancer chemotherapy and pharmacology. 85, 2, p. 345-352 8 p.

研究成果: Contribution to journalArticle

Phase I dose-escalation trial to repurpose propagermanium, an oral CCL2 inhibitor, in patients with breast cancer

Masuda, T., Noda, M., Kogawa, T., Kitagawa, D., Hayashi, N., Jomori, T., Nakanishi, Y., Nakayama, K. I., Ohno, S. & Mimori, K., 3 1 2020, : : Cancer Science. 111, 3, p. 924-931 8 p.

研究成果: Contribution to journalArticle

公開
2 引用 (Scopus)
公開

Prognostic Significance of PD-1, PD-L1 and CD8 Gene Expression Levels in Gastric Cancer

Ito, S., Masuda, T., Noda, M., Hu, Q., Shimizu, D., Kuroda, Y., Eguchi, H., Tobo, T., Utsunomiya, T. & Mimori, K., 7 1 2020, : : Oncology (Switzerland). 98, 7, p. 501-511 11 p.

研究成果: Contribution to journalArticle

Reply

Takeishi, K., Ikegami, T., Yoshizumi, T., Fujimori, N. & Mori, M., 5 1 2020, : : Liver Transplantation. 26, 5, p. 727-728 2 p.

研究成果: Contribution to journalLetter

Right hepatic venous system variation in living donors: a three-dimensional CT analysis

Watanabe, A., Yoshizumi, T., Harimoto, N., Kogure, K., Ikegami, T., Harada, N., Itoh, S., Takeishi, K., Mano, Y., Yoshiya, S., Morinaga, A., Araki, K., Kubo, N., Mori, M. & Shirabe, K., 8 1 2020, : : British Journal of Surgery. 107, 9, p. 1192-1198 7 p.

研究成果: Contribution to journalArticle

公開

Risk factors for the metabolic syndrome components of hypertension, diabetes mellitus, and dyslipidemia after living donor liver transplantation

Toshima, T., Yoshizumi, T., Inokuchi, S., Kosai-Fujimoto, Y., Kurihara, T., Yoshiya, S., Mano, Y., Takeishi, K., Itoh, S., Harada, N., Ikegami, T., Soejima, Y., Shimokawa, M., Maehara, Y. & Mori, M., 4 2020, : : HPB. 22, 4, p. 511-520 10 p.

研究成果: Contribution to journalArticle

SF3B4 plays an oncogenic role in esophageal squamous cell carcinoma

Kidogami, S., Iguchi, T., Sato, K., Yoshikawa, Y., Hu, Q., Nambara, S., Komatsu, H., Ueda, M., Kuroda, Y., Masuda, T., Mori, M., Doki, Y. & Mimori, K., 5 2020, : : Anticancer research. 40, 5, p. 2941-2946 6 p.

研究成果: Contribution to journalArticle

Shoulder ultrasound and serum lactate dehydrogenase predict inadequate response to glucocorticoid treatment in patients with polymyalgia rheumatica

Ayano, M., Arinobu, Y., Tsukamoto, H., Ota, S. I., Misaki, K., Nishimura, K., Kimoto, Y., Mitoma, H., Akahoshi, M., Akashi, K., Horiuchi, T. & Niiro, H., 7 1 2020, : : Rheumatology International. 40, 7, p. 1101-1109 9 p.

研究成果: Contribution to journalArticle

Surgery-related predictable risk factors influencing postoperative clinical outcomes for thoracic myelopathy caused by ossification of the posterior longitudinal ligament: A multicenter retrospective study

Saiwai, H., Okada, S., Hayashida, M., Harimaya, K., Matsumoto, Y., Kawaguchi, K. I., Kobayakawa, K., Maeda, T., Ohta, H., Shirasawa, K., Tsuchiya, K., Terada, K., Kaji, K., Arizono, T., Saito, T., Fujiwara, M., Iwamoto, Y. & Nakashima, Y., 5 2020, : : Journal of Neurosurgery: Spine. 32, 5, p. 703-709 7 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

The beneficial aspects of spasticity in relation to ambulatory ability in mice with spinal cord injury

Yoshizaki, S., Yokota, K., Kubota, K., Saito, T., Tanaka, M., Konno, D. J., Maeda, T., Matsumoto, Y., Nakashima, Y. & Okada, S., 5 1 2020, : : Spinal Cord. 58, 5, p. 537-543 7 p.

研究成果: Contribution to journalArticle

The Expression Level of PD-L1 (CD274) mRNA in Peripheral Blood Is a Potential Biomarker for Predicting Recurrence in Breast Cancer

Masuda, T., Noda, M., Kitagawa, A., Hu, Q., Fujii, A., Ito, S., Kosai, K., Ando, Y., Matsumoto, Y., Ohtsu, H., Uchida, H., Ohno, S. & Mimori, K., 7 1 2020, : : Anticancer research. 40, 7, p. 3733-3742 10 p.

研究成果: Contribution to journalArticle

The factors related to the poor ADL in the patients with osteoporotic vertebral fracture after instrumentation surgery

Murata, K., Matsuoka, Y., Nishimura, H., Endo, K., Suzuki, H., Takamatsu, T., Sawaji, Y., Aihara, T., Kusakabe, T., Maekawa, A., Yamamoto, K., Watanabe, K., Kaito, T., Terai, H., Tamai, K., Tagami, A., Yoshii, T., Harimaya, K., Kawaguchi, K., Kimura, A. および30人, Inoue, G., Nakano, A., Sakai, D., Hiyama, A., Ikegami, S., Ohtori, S., Furuya, T., Orita, S., Imagama, S., Kobayashi, K., Kiyasu, K., Murakami, H., Yoshioka, K., Seki, S., Hongo, M., Kakutani, K., Yurube, T., Aoki, Y., Uei, H., Ajiro, Y., Takahata, M., Endo, H., Abe, T., Nakanishi, K., Watanabe, K., Okada, E., Hosogane, N., Funao, H., Isogai, N. & Ishii, K., 7 1 2020, : : European Spine Journal. 29, 7, p. 1597-1605 9 p.

研究成果: Contribution to journalArticle

The Prognostic Impact of Leucine-Rich α-2-Glycoprotein-1 in Cholangiocarcinoma and Its Association With the IL-6/TGF-β1 Axis

Jin, Z., Kobayashi, S., Gotoh, K., Takahashi, T., Eguchi, H., Naka, T., Mori, M. & Doki, Y., 8 2020, : : Journal of Surgical Research. 252, p. 147-155 9 p.

研究成果: Contribution to journalArticle

Usefulness of daily folic acid supplementation during methotrexate treatment of Japanese patients with rheumatoid arthritis

Sasaki, K., Tsuji, T., Kimoto, Y., Yanagihara, Y., Masuguchi, K., Chikamori, A., Watanabe, H., Murakami, T., Oryoji, D., Hashimoto, M., Horiuchi, T. & Egashira, N., 1 1 2020, (受理済み/印刷中) : : Modern Rheumatology.

研究成果: Contribution to journalArticle

YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma

Omori, H., Nishio, M., Masuda, M., Miyachi, Y., Ueda, F., Nakano, T., Sato, K., Mimori, K., Taguchi, K., Hikasa, H., Nishina, H., Tashiro, H., Kiyono, T., Mak, T. W., Nakao, K., Nakagawa, T., Maehama, T. & Suzuki, A., 2020, : : Science Advances. 6, 12, eaay3324.

研究成果: Contribution to journalArticle

公開
1 引用 (Scopus)
2019

Accumulation of gold nano-rods in the failing heart of transgenic mice with the cardiac-specific expression of TNF-α

Higuchi, Y., Niidome, T., Miyamoto, Y., Komohara, Y., Tokunou, T., Kubota, T. & Horiuchi, T., 3 15 2019, : : Heart and Vessels. 34, 3, p. 538-544 7 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient

Hayashi, N., Kuroda, Y., Saito, T., Tsuruda, Y., Niida, A., Otsu, H., Eguchi, H., Masuda, T., Suzuki, Y., Natsugoe, S. & Mimori, K., 9 10 2019, : : Surgery today. 49, 9, p. 738-747 10 p.

研究成果: Contribution to journalArticle

Age-related remodelling of oesophageal epithelia by mutated cancer drivers

Yokoyama, A., Kakiuchi, N., Yoshizato, T., Nannya, Y., Suzuki, H., Takeuchi, Y., Shiozawa, Y., Sato, Y., Aoki, K., Kim, S. K., Fujii, Y., Yoshida, K., Kataoka, K., Nakagawa, M. M., Inoue, Y., Hirano, T., Shiraishi, Y., Chiba, K., Tanaka, H., Sanada, M. および20人, Nishikawa, Y., Amanuma, Y., Ohashi, S., Aoyama, I., Horimatsu, T., Miyamoto, S., Tsunoda, S., Sakai, Y., Narahara, M., Brown, J. B., Sato, Y., Sawada, G., Mimori, K., Minamiguchi, S., Haga, H., Seno, H., Miyano, S., Makishima, H., Muto, M. & Ogawa, S., 1 17 2019, : : Nature. 565, 7739, p. 312-317 6 p.

研究成果: Contribution to journalArticle

86 引用 (Scopus)

A Hydrogen Peroxide Activatable Gemcitabine Prodrug for the Selective Treatment of Pancreatic Ductal Adenocarcinoma

Matsushita, K., Okuda, T., Mori, S., Konno, M., Eguchi, H., Asai, A., Koseki, J., Iwagami, Y., Yamada, D., Akita, H., Asaoka, T., Noda, T., Kawamoto, K., Gotoh, K., Kobayashi, S., Kasahara, Y., Morihiro, K., Satoh, T., Doki, Y., Mori, M. および2人, Ishii, H. & Obika, S., 2019, : : ChemMedChem. 14, 15, p. 1384-1391 8 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)

A multiethnic meta-analysis defined the association of rs12946942 with severe adolescent idiopathic scoliosis

Japan Scoliosis Clinical Research Group (JSCRG), 5 1 2019, : : Journal of Human Genetics. 64, 5, p. 493-498 6 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

Application of C. elegans cancer screening test for the detection of pancreatic tumor in genetically engineered mice

Ueda, Y., Kawamoto, K., Konno, M., Noguchi, K., Kaifuchi, S., Satoh, T., Eguchi, H., Doki, Y., Hirotsu, T., Mori, M. & Ishii, H., 2019, : : Oncotarget. 10, 52, p. 5412-5418 7 p.

研究成果: Contribution to journalArticle

公開
2 引用 (Scopus)

ASO Author Reflections: ARL4C and Peritoneal Dissemination in Gastric Cancer

Hu, Q. & Mimori, K., 12 1 2019, : : Annals of Surgical Oncology. 26, 1 p.

研究成果: Contribution to journalComment/debate

CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines

Takaki-Kuwahara, A., Arinobu, Y., Miyawaki, K., Yamada, H., Tsuzuki, H., Irino, K., Ayano, M., Kimoto, Y., Mitoma, H., Akahoshi, M., Tsukamoto, H., Horiuchi, T., Niiro, H. & Akashi, K., 8 30 2019, : : Arthritis Research and Therapy. 21, 1, 198.

研究成果: Contribution to journalArticle

公開
3 引用 (Scopus)
3 引用 (Scopus)

CKAP4, a DKK1 receptor, is a biomarker in exosomes derived from pancreatic cancer and a molecular target for therapy

Kimura, H., Yamamoto, H., Harada, T., Fumoto, K., Osugi, Y., Sada, R., Maehara, N., Hikita, H., Mori, S., Eguchi, H., Ikawa, M., Takehara, T. & Kikuchi, A., 1 1 2019, : : Clinical Cancer Research. 25, 6, p. 1936-1947 12 p.

研究成果: Contribution to journalArticle

8 引用 (Scopus)

Complications after spinal fixation surgery for osteoporotic vertebral collapse with neurological deficits: Japan Association of Spine Surgeons with ambition multicenter study

Sakai, Y., Kaito, T., Takenaka, S., Yamashita, T., Makino, T., Hosogane, N., Nojiri, K., Suzuki, S., Okada, E., Watanabe, K., Funao, H., Isogai, N., Ueda, S., Hikata, T., Shiono, Y., Watanabe, K., Katsumi, K., Fujiwara, H., Nagamoto, Y., Terai, H. および47人, Tamai, K., Matsuoka, Y., Suzuki, H., Nishimura, H., Tagami, A., Yamada, S., Adachi, S., Ohtori, S., Orita, S., Furuya, T., Yoshii, T., Ushio, S., Inoue, G., Miyagi, M., Saito, W., Imagama, S., Ando, K., Sakai, D., Nukaga, T., Kiyasu, K., Kimura, A., Inoue, H., Nakano, A., Harimaya, K., Doi, T., Kawaguchi, K., Yokoyama, N., Oishi, H., Ikegami, S., Futatsugi, T., Shimizu, M., Kakutani, K., Yurube, T., Oshima, M., Uei, H., Aoki, Y., Takahata, M., Iwata, A., Seki, S., Murakami, H., Yoshioka, K., Endo, H., Hongo, M., Nakanishi, K., Abe, T., Tsukanishi, T. & Ishii, K., 11 2019, : : Journal of Orthopaedic Science. 24, 6, p. 985-990 6 p.

研究成果: Contribution to journalArticle