研究成果

2018

A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell

Hashiramoto, A., Konishi, Y., Murayama, K., Kawasaki, H., Yoshida, K., Tsumiyama, K., Tanaka, K., Mizuhara, M., Shiotsuki, T., Kitamura, H., Komai, K., Kimura, T., Yagita, H., Shiozawa, K. & Shiozawa, S., 2 9 2018, : : Journal of Biological Chemistry. 293, 6, p. 1933-1943 11 p.

研究成果: Contribution to journalArticle

3 引用 (Scopus)

Beneficial use of serum ferritin and heme oxygenase-1 as biomarkers in adult-onset Still’s disease: A multicenter retrospective study

Kirino, Y., Kawaguchi, Y., Tada, Y., Tsukamoto, H., Ota, T., Iwamoto, M., Takahashi, H., Nagasawa, K., Takei, S., Horiuchi, T., Ichida, H., Minota, S., Ueda, A., Ohta, A. & Ishigatsubo, Y., 9 3 2018, : : Modern Rheumatology. 28, 5, p. 858-864 7 p.

研究成果: Contribution to journalArticle

4 引用 (Scopus)

Cancer evolution and heterogeneity

Mimori, K., Saito, T., Niida, A. & Miyano, S., 9 2018, : : Annals of Gastroenterological Surgery. 2, 5, p. 332-338 7 p.

研究成果: Contribution to journalReview article

公開
5 引用 (Scopus)

Cardiac sarcoidosis concomitant with large-vessel aortitis detected by 18F-fluorodeoxyglucose positron emission tomography

Higuchi, Y., Kimoto, Y., Tanoue, R., Tokunou, T., Tomonari, K., Maeda, T. & Horiuchi, T., 2018, : : Internal Medicine. 57, 11, p. 1601-1604 4 p.

研究成果: Contribution to journalArticle

Cell-free culture conditioned medium elicits pancreatic β cell lineage-specific epigenetic reprogramming in mice

Kawamoto, K., Ohashi, T., Konno, M., Nishida, N., Koseki, J., Matsui, H., Sakai, D., Kudo, T., Eguchi, H., Satoh, T., Doki, Y., Mori, M. & Ishii, H., 9 2018, : : Oncology Letters. 16, 3, p. 3255-3259 5 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)

Circulating Pre-microRNA-488 in peripheral blood is a potential biomarker for predicting recurrence in breast cancer

Masuda, T., Shinden, Y., Noda, M., Ueo, H., Hu, Q., Yoshikawa, Y., Tsuruda, Y., Kuroda, Y., Ito, S., Eguchi, H., Ohno, S. & Mimori, K., 8 2018, : : Anticancer research. 38, 8, p. 4515-4523 9 p.

研究成果: Contribution to journalArticle

14 引用 (Scopus)

Class III β-tubulin overexpression induces chemoresistance to eribulin in a leiomyosarcoma cell line

Yahiro, K., Matsumoto, Y., Fukushi, J. I., Kawaguchi, K. I., Endo, M., Setsu, N., IIda, K., Fukushima, S., Nakagawa, M., Kimura, A., Oda, Y. & Nakashima, Y., 2018, : : Analytical Cellular Pathology. 2018, 8987568.

研究成果: Contribution to journalArticle

2 引用 (Scopus)

Clinical and anti-aging effect of mud-bathing therapy for patients with fibromyalgia

Maeda, T., Kudo, Y., Horiuchi, T. & Makino, N., 7 1 2018, : : Molecular and cellular biochemistry. 444, 1-2, p. 87-92 6 p.

研究成果: Contribution to journalArticle

7 引用 (Scopus)

Clinical Impact of Preoperative Sarcopenia on the Postoperative Outcomes After Pancreas Transplantation

Fukuda, Y., Asaoka, T., Eguchi, H., Sasaki, K., Iwagami, Y., Yamada, D., Noda, T., Kawamoto, K., Gotoh, K., Kobayashi, S., Ito, T., Takeda, Y., Tanemura, M., Mori, M. & Doki, Y., 10 1 2018, : : World journal of surgery. 42, 10, p. 3364-3371 8 p.

研究成果: Contribution to journalArticle

3 引用 (Scopus)

Clinical outcome and prognostic factors of malignant spinal dumbbell tumors

Matsumoto, Y., Kawaguchi, K., Fukushi, J. I., Endo, M., Setsu, N., Iida, K., Baba, S., Saiwai, H., Matsushita, A., Hayashida, M., Okada, S. & Nakashima, Y., 2018, : : Spine Surgery and Related Research. 2, 4, p. 317-323 7 p.

研究成果: Contribution to journalArticle

公開

Clinical significance of CD13 and epithelial mesenchymal transition (EMT) markers in hepatocellular carcinoma

Yamanaka, C., Wada, H., Eguchi, H., Hatano, H., Gotoh, K., Noda, T., Yamada, D., Asaoka, T., Kawamoto, K., Nagano, H., Doki, Y. & Mori, M., 1 1 2018, : : Japanese journal of clinical oncology. 48, 1, p. 52-60 9 p.

研究成果: Contribution to journalArticle

10 引用 (Scopus)

C-met affects gemcitabine resistance during carcinogenesis in a mouse model of pancreatic cancer

Noguchi, K., Konno, M., Eguchi, H., Kawamoto, K., Mukai, R., Nishida, N., Koseki, J., Wada, H., Akita, H., Satoh, T., Marubashi, S., Nagano, H., Doki, Y., Mori, M. & Ishii, H., 8 2018, : : Oncology Letters. 16, 2, p. 1892-1898 7 p.

研究成果: Contribution to journalArticle

5 引用 (Scopus)

Combination gemcitabine and WT1 peptide vaccination improves progression-free survival in advanced pancreatic ductal adenocarcinoma: A phase II randomized study

Nishida, S., Ishikawa, T., Egawa, S., Koido, S., Yanagimoto, H., Ishii, J., Kanno, Y., Kokura, S., Yasuda, H., Oba, M. S., Sato, M., Morimoto, S., Fujiki, F., Eguchi, H., Nagano, H., Kumanogoh, A., Unno, M., Kon, M., Shimada, H., Ito, K. および4人, Homma, S., Oka, Y., Morita, S. & Sugiyama, H., 3 1 2018, : : Cancer Immunology Research. 6, 3, p. 320-331 12 p.

研究成果: Contribution to journalArticle

15 引用 (Scopus)

Combined mutation of Apc, Kras, and Tgfbr2 effectively drives metastasis of intestinal cancer

Sakai, E., Nakayama, M., Oshima, H., Kouyama, Y., Niida, A., Fujii, S., Ochiai, A., Nakayama, K. I., Mimori, K., Suzuki, Y., Hong, C. P., Ock, C. Y., Kim, S. J. & Oshima, M., 3 1 2018, : : Cancer Research. 78, 5, p. 1334-1346 13 p.

研究成果: Contribution to journalArticle

18 引用 (Scopus)

Comparison of Adverse Events and Outcomes Between Patients With and Without Drain Insertion After Hepatectomy: A Propensity Score-Matched, Multicenter, Prospective Observational Cohort Study in Japan (CSGO-HBP-001)

Yamada, T., Gotoh, K., Marubashi, S., Asaoka, T., Miyamoto, A., Kobayashi, S., Eguchi, H., Shimizu, J., Kim, Y., Tsujie, M., Noda, T., Yokoyama, S., Takeda, Y., Mori, M., Doki, Y. & Nagano, H., 8 1 2018, : : World journal of surgery. 42, 8, p. 2561-2569 9 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

Control of inferior vena cava injury during laparoscopic surgery using a double balloon-equipped central venous catheter: proof of concept in a live porcine model

Iwashita, Y., Uchida, H., Takayama, H., Ichimanda, M., Taniguchi, K., Kiguchi, H., Sakaguchi, T., Fujishima, H., Saga, K., Tada, K., Hara, T., Watanabe, K., Hirashita, T., Endo, Y., Ohta, M. & Inomata, M., 5 1 2018, : : Surgical endoscopy. 32, 5, p. 2397-2401 5 p.

研究成果: Contribution to journalArticle

公開

CTGF mediates tumor–stroma interactions between hepatoma cells and hepatic stellate cells to accelerate HCC progression

Makino, Y., Hikita, H., Kodama, T., Shigekawa, M., Yamada, R., Sakamori, R., Eguchi, H., Morii, E., Yokoi, H., Mukoyama, M., Hiroshi, S., Tatsumi, T. & Takehara, T., 9 1 2018, : : Cancer Research. 78, 17, p. 4902-4914 13 p.

研究成果: Contribution to journalArticle

12 引用 (Scopus)

Cytolytic activity (CYT) score is a prognostic biomarker reflecting host immune status in hepatocellular carcinoma (HCC)

Wakiyama, H., Masuda, T., Motomura, Y., Qingjiang, H. U., Tobo, T., Eguchi, H., Sakamoto, K., Hirakawa, M., Honda, H. & Mimori, K., 12 2018, : : Anticancer research. 38, 12, p. 6631-6638 8 p.

研究成果: Contribution to journalArticle

4 引用 (Scopus)

E-cadherin regulates proliferation of colorectal cancer stem cells through NANOG

Tamura, S., Isobe, T., Ariyama, H., Nakano, M., Kikushige, Y., Takaishi, S., Kusaba, H., Takenaka, K., Ueki, T., Nakamura, M., Akashi, K. & Baba, E., 8 2018, : : Oncology reports. 40, 2, p. 693-703 11 p.

研究成果: Contribution to journalArticle

5 引用 (Scopus)

Effect of cartilaginous endplates on extruded disc resorption in lumbar disc herniation

Kawaguchi, K., Harimaya, K., Matsumoto, Y., Hayashida, M., Okada, S., Iida, K., Kato, G., Tsuchiya, K., Doi, T., Oda, Y., Iwamoto, Y. & Nakashima, Y., 4 2018, : : PloS one. 13, 4, e0195946.

研究成果: Contribution to journalArticle

3 引用 (Scopus)

Effect of herbal medicine daikenchuto on oral and enteral caloric intake after liver transplantation: A multicenter, randomized controlled trial

Kaido, T., Shinoda, M., Inomata, Y., Yagi, T., Akamatsu, N., Takada, Y., Ohdan, H., Shimamura, T., Ogura, Y., Eguchi, S., Eguchi, H., Ogata, S., Yoshizumi, T., Ikegami, T., Yamamoto, M., Morita, S. & Uemoto, S., 10 2018, : : Nutrition. 54, p. 68-75 8 p.

研究成果: Contribution to journalArticle

3 引用 (Scopus)
12 引用 (Scopus)
3 引用 (Scopus)

Epithelial-mesenchymal transition is activated in CD44-positive malignant ascites tumor cells of gastrointestinal cancer

Nakano, M., Ito, M., Tanaka, R., Ariyama, H., Mitsugi, K., Makiyama, A., Uchino, K., Esaki, T., Tsuruta, N., Hanamura, F., Yamaguchi, K., Okumura, Y., Sagara, K., Takayoshi, K., Nio, K., Tsuchihashi, K., Tamura, S., Shimokawa, H., Arita, S., Miyawaki, K. および3人, Kusaba, H., Akashi, K. & Baba, E., 11 2018, : : Cancer Science. 109, 11, p. 3461-3470 10 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

Establishment of an antibody specific for cancer-associated haptoglobin: A possible implication of clinical investigation

Nishino, K., Koda, S., Kataoka, N., Takamatsu, S., Nakano, M., Ikeda, S., Kamamatsu, Y., Morishita, K., Moriwaki, K., Eguchi, H., Yamamoto, E., Kikkawa, F., Tomita, Y., Kamada, Y. & Miyoshi, E., 2018, : : Oncotarget. 9, 16, p. 12732-12744 13 p.

研究成果: Contribution to journalArticle

5 引用 (Scopus)

Fetal hepatocyte-derived culture medium elicits adipocyte differentiation to bile duct cell lineages in a mouse model

Ogawa, H., Konno, M., Kawamoto, K., Nishida, N., Koseki, J., Mizushima, T., Satoh, T., Eguchi, H., Doki, Y., Mori, M. & Ishii, H., 5 2018, : : Biomedical Reports. 8, 5, p. 497-499 3 p.

研究成果: Contribution to journalArticle

First-line chemotherapy with S-1 alone or S-1 plus cisplatin for elderly patients with advanced gastric cancer: a multicenter propensity score matched study

Makiyama, A., Kunieda, K., Noguchi, M., Kajiwara, T., Tamura, T., Takeda, K., Sugiyama, J., Minashi, K., Moriwaki, T., Sugimoto, N., Nagase, M., Negoro, Y., Tsuda, T., Shimodaira, H., Okano, N., Tsuji, A., Sakai, D., Yanagihara, K., Ueda, S., Tamura, S. および15人, Otsu, S., Honda, T., Matsushita, Y., Okuno, T., Kashiwada, T., Nozaki, A., Ebi, M., Okuda, H., Shimokawa, M., Hironaka, S., Hyodo, I., Baba, E., Boku, N., Muro, K. & Esaki, T., 9 1 2018, : : Gastric Cancer. 21, 5, p. 792-801 10 p.

研究成果: Contribution to journalArticle

4 引用 (Scopus)

Gastrointestinal Graft-versus-Host Disease Is a Risk Factor for Postengraftment Bloodstream Infection in Allogeneic Hematopoietic Stem Cell Transplant Recipients

Mori, Y., Yoshimoto, G., Nishida, R., Sugio, T., Miyawaki, K., Shima, T., Nagasaki, Y., Miyake, N., Harada, Y., Kunisaki, Y., Kamezaki, K., Numata, A., Kato, K., Shiratsuchi, M., Maeda, T., Takenaka, K., Iwasaki, H., Shimono, N., Akashi, K. & Miyamoto, T., 11 2018, : : Biology of Blood and Marrow Transplantation. 24, 11, p. 2302-2309 8 p.

研究成果: Contribution to journalArticle

4 引用 (Scopus)

GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12

Tanikawa, C., Kamatani, Y., Takahashi, A., Momozawa, Y., Leveque, K., Nagayama, S., Mimori, K., Mori, M., Ishii, H., Inazawa, J., Yasuda, J., Tsuboi, A., Shimizu, A., Sasaki, M., Yamaji, T., Sawada, N., Iwasaki, M., Tsugane, S., Naito, M., Wakai, K. および7人, Koyama, T., Takezaki, T., Yuji, K., Murakami, Y., Nakamura, Y., Kubo, M. & Matsuda, K., 5 3 2018, : : Carcinogenesis. 39, 5, p. 652-660 9 p.

研究成果: Contribution to journalArticle

15 引用 (Scopus)

Haptoglobin phenotype is a critical factor in the use of fucosylated haptoglobin for pancreatic cancer diagnosis

Morishita, K., Ito, N., Koda, S., Maeda, M., Nakayama, K., Yoshida, K., Takamatsu, S., Yamada, M., Eguchi, H., Kamada, Y. & Miyoshi, E., 12 2018, : : Clinica Chimica Acta. 487, p. 84-89 6 p.

研究成果: Contribution to journalArticle

8 引用 (Scopus)

Hepatocellular carcinoma due to a baffle obstruction after the mustard operation: A case report

Yoshihara, T., Sakamori, R., Furuta, K., Shigekawa, M., Yamada, R., Kodama, T., Hikita, H., Yakushijin, T., Tatsumi, T., Sakata, Y., Eguchi, H., Sawa, Y. & Takehara, T., 6 2018, : : Hepatology. 67, 6, p. 2471-2473 3 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

Hereditary angioedema from 1888 to 2018-progress and problems

Horiuchi, T., 2018, : : Internal Medicine. 57, 21, p. 3065-3066 2 p.

研究成果: Contribution to journalEditorial

3 引用 (Scopus)
3 引用 (Scopus)

Human pancreatic α- to β-cell area ratio increases after type 2 diabetes onset

Fujita, Y., Kozawa, J., Iwahashi, H., Yoneda, S., Uno, S., Eguchi, H., Nagano, H., Imagawa, A. & Shimomura, I., 11 2018, : : Journal of Diabetes Investigation. 9, 6, p. 1270-1282 13 p.

研究成果: Contribution to journalArticle

5 引用 (Scopus)

Hypoxia-Induced PLOD2 is a Key Regulator in Epithelial-Mesenchymal Transition and Chemoresistance in Biliary Tract Cancer

Okumura, Y., Noda, T., Eguchi, H., Sakamoto, T., Iwagami, Y., Yamada, D., Asaoka, T., Wada, H., Kawamoto, K., Gotoh, K., Kobayashi, S., Takeda, Y., Tanemura, M., Umeshita, K., Doki, Y. & Mori, M., 11 1 2018, : : Annals of Surgical Oncology. 25, 12, p. 3728-3737 10 p.

研究成果: Contribution to journalArticle

11 引用 (Scopus)

Identification of ARL4C as a Peritoneal Dissemination-Associated Gene and Its Clinical Significance in Gastric Cancer

Hu, Q., Masuda, T., Sato, K., Tobo, T., Nambara, S., Kidogami, S., Hayashi, N., Kuroda, Y., Ito, S., Eguchi, H., Saeki, H., Oki, E., Maehara, Y. & Mimori, K., 3 1 2018, : : Annals of Surgical Oncology. 25, 3, p. 745-753 9 p.

研究成果: Contribution to journalArticle

13 引用 (Scopus)

Identification of UHRF2 as a Negative Regulator of Epithelial-Mesenchymal Transition and Its Clinical Significance in Esophageal Squamous Cell Carcinoma

Iguchi, T., Ueda, M., Masuda, T., Nambara, S., Kidogami, S., Komatsu, H., Sato, K., Tobo, T., Ogawa, Y., Hu, Q., Saito, T., Hirata, H., Sakimura, S., Uchi, R., Hayashi, N., Ito, S., Eguchi, H., Sugimachi, K., Maehara, Y. & Mimori, K., 8 1 2018, : : Oncology (Switzerland). 95, 3, p. 179-187 9 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)

Impact of Splenic Volume and Splenectomy on Prognosis of Hepatocellular Carcinoma Within Milan Criteria After Curative Hepatectomy

Takeishi, K., Kawanaka, H., Itoh, S., Harimoto, N., Ikegami, T., Yoshizumi, T., Shirabe, K. & Maehara, Y., 4 1 2018, : : World journal of surgery. 42, 4, p. 1120-1128 9 p.

研究成果: Contribution to journalArticle

5 引用 (Scopus)

Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts

Dulin, J. N., Adler, A. F., Kumamaru, H., Poplawski, G. H. D., Lee-Kubli, C., Strobl, H., Gibbs, D., Kadoya, K., Fawcett, J. W., Lu, P. & Tuszynski, M. H., 12 1 2018, : : Nature communications. 9, 1, 84.

研究成果: Contribution to journalArticle

26 引用 (Scopus)

Laparoscopic liver resection in cirrhotic patients with specific reference to a difficulty scoring system

Uchida, H., Iwashita, Y., Tada, K., Saga, K., Takayama, H., Hirashita, T., Endo, Y., Ohta, M. & Inomata, M., 5 1 2018, : : Langenbeck's Archives of Surgery. 403, 3, p. 371-377 7 p.

研究成果: Contribution to journalArticle

5 引用 (Scopus)

Layer-by-layer cell coating technique using extracellular matrix facilitates rapid fabrication and function of pancreatic β-cell spheroids

Fukuda, Y., Akagi, T., Asaoka, T., Eguchi, H., Sasaki, K., Iwagami, Y., Yamada, D., Noda, T., Kawamoto, K., Gotoh, K., Kobayashi, S., Mori, M., Doki, Y. & Akashi, M., 4 2018, : : Biomaterials. 160, p. 82-91 10 p.

研究成果: Contribution to journalArticle

21 引用 (Scopus)

Long-term efficacy of infliximab treatment and the predictors of treatment outcomes in patients with refractory uveitis associated with Behçet's disease

Ueda, S., Akahoshi, M., Takeda, A., Inoue, Y., Omoto, A., Ayano, M., Kimoto, Y., Mitoma, H., Arinobu, Y., Niiro, H., Tsukamoto, H., Horiuchi, T., Hikita, S-I., Fukuhara, T., Ishibashi, T., Sonoda, K-H. & Akashi, K., 3 2018, : : European journal of rheumatology. 5, 1, p. 9-15 7 p.

研究成果: Contribution to journalArticle

MAPLE-PD trial (Mesenteric Approach vs. Conventional Approach for Pancreatic Cancer during Pancreaticoduodenectomy): Study protocol for a multicenter randomized controlled trial of 354 patients with pancreatic ductal adenocarcinoma 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

Hirono, S., Kawai, M., Okada, K. I., Fujii, T., Sho, M., Satoi, S., Amano, R., Eguchi, H., Mataki, Y., Nakamura, M., Matsumoto, I., Baba, H., Tani, M., Kawabata, Y., Nagakawa, Y., Yamada, S., Murakami, Y., Shimokawa, T. & Yamaue, H., 11 8 2018, : : Trials. 19, 1, 613.

研究成果: Contribution to journalArticle

公開
9 引用 (Scopus)

Minimally invasive liver resection for hepatocellular carcinoma of patients with liver damage B: A propensity score-based analysis

Noda, T., Eguchi, H., Iwagami, Y., Yamada, D., Asaoka, T., Gotoh, K., Kawamoto, K., Kobayashi, S., Hashimoto, Y., Takeda, Y., Tanemura, M., Umeshita, K., Doki, Y. & Mori, M., 6 2018, : : Hepatology Research. 48, 7, p. 539-548 10 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)

Molecular mechanisms of action of anti-TNF-α agents – Comparison among therapeutic TNF-α antagonists

Mitoma, H., Horiuchi, T., Tsukamoto, H. & Ueda, N., 1 2018, : : Cytokine. 101, p. 56-63 8 p.

研究成果: Contribution to journalArticle

51 引用 (Scopus)

Nivolumab-induced thyroid dysfunction lacking antithyroid antibody is frequently evoked in Japanese patients with malignant melanoma

Yano, S., Ashida, K., Nagata, H., Ohe, K., Wada, N., Takeichi, Y., Hanada, Y., Ibayashi, Y., Wang, L., Sakamoto, S., Sakamoto, R., Uchi, H., Shiratsuchi, M., Furue, M., Nomura, M. & Ogawa, Y., 6 8 2018, : : BMC Endocrine Disorders. 18, 1, 36.

研究成果: Contribution to journalArticle

3 引用 (Scopus)

Outcomes following liver resection for multinodular barcelona clinic liver cancer-B hepatocellular carcinoma

Matsukuma, S., Sakamoto, K., Tokuhisa, Y., Tokumitsu, Y., Matsui, H., Kanekiyo, S., Tomochika, S., Iida, M., Suzuki, N., Takeda, S., Ueno, T., Wada, H., Kobayashi, S., Saeki, I., Eguchi, H., Sakon, M., Sakaida, I. & Nagano, H., 11 2018, : : Oncology Letters. 16, 5, p. 6383-6392 10 p.

研究成果: Contribution to journalArticle

3 引用 (Scopus)

Overexpression of FGFR1 promotes peritoneal dissemination via epithelial-to-mesenchymal transition in gastric cancer

Shimizu, D., Saito, T., Shuhei, I. T. O., Masuda, T., Kurashige, J., Kuroda, Y., Eguchi, H., Kodera, Y. & Mimori, K., 7 1 2018, : : Cancer Genomics and Proteomics. 15, 4, p. 313-320 8 p.

研究成果: Contribution to journalArticle

4 引用 (Scopus)

PD-1+ TIM-3+ T cells in malignant ascites predict prognosis of gastrointestinal cancer

Nakano, M., Ito, M., Tanaka, R., Yamaguchi, K., Ariyama, H., Mitsugi, K., Yoshihiro, T., Ohmura, H., Tsuruta, N., Hanamura, F., Sagara, K., Okumura, Y., Nio, K., Tsuchihashi, K., Arita, S., Kusaba, H., Akashi, K. & Baba, E., 9 2018, : : Cancer Science. 109, 9, p. 2986-2992 7 p.

研究成果: Contribution to journalArticle

9 引用 (Scopus)