研究成果 2003 2019

2019

2,5-Dimethylcelecoxib prevents isoprenaline-induced cardiomyocyte hypertrophy and cardiac fibroblast activation by inhibiting Akt-mediated GSK-3 phosphorylation

Morishige, S., Takahashi-Yanaga, F., Ishikane, S., arioka, M., Igawa, K., Kuroo, A., Tomooka, K., Shiose, A. & Sasaguri, T., 10 1 2019, : : Biochemical Pharmacology. 168, p. 82-90 9 p.

研究成果: ジャーナルへの寄稿記事

Glycogen Synthase Kinase 3
Phosphorylation
Cardiomegaly
Fibroblasts
Isoproterenol

A Novel Osteotomy Preparation Technique to Preserve Implant Site Viability and Enhance Osteogenesis

Chen, C-H., Coyac, B. R., Arioka, M., Leahy, B., Tulu, U. S., Aghvami, M., Holst, S., Hoffmann, W., Quarry, A., Bahat, O., Salmon, B., Brunski, J. B. & Helms, J. A., 2 1 2019, : : Journal of Clinical Medicine. 8, 2

研究成果: ジャーナルへの寄稿記事

Osteotomy
Osteogenesis
Bone and Bones
Mandrillus
Reconstructive Surgical Procedures

Glycogen synthase kinase-3 inhibitor as a multi-targeting anti-rheumatoid drug

arioka, M. & Takahashi-Yanaga, F., 7 1 2019, : : Biochemical Pharmacology. 165, p. 207-213 7 p.

研究成果: ジャーナルへの寄稿評論記事

Glycogen Synthase Kinase 3
Rheumatoid Arthritis
Pharmaceutical Preparations
Protein-Serine-Threonine Kinases
Pathology
公開
Genetic Polymorphisms
Caffeine
Healthy Volunteers
Heart Rate
Blood Pressure

Molecular Basis for Periodontal Ligament Adaptation to In Vivo Loading

Zhang, X., Yuan, X., Xu, Q., arioka, M., Van Brunt, L. A., Shi, Y., Brunski, J. & Helms, J. A., 3 1 2019, : : Journal of Dental Research. 98, 3, p. 331-338 8 p.

研究成果: ジャーナルへの寄稿記事

Periodontal Ligament
Diet
Alveolar Bone Loss
Food
Mastication
1 引用 (Scopus)

Osteoporotic Changes in the Periodontium Impair Alveolar Bone Healing

arioka, M., Zhang, X., Li, Z., Tulu, U. S., Liu, Y., Wang, L., Yuan, X. & Helms, J. A., 4 1 2019, : : Journal of Dental Research. 98, 4, p. 450-458 9 p.

研究成果: ジャーナルへの寄稿記事

Periodontium
Periodontal Ligament
Jaw
Skeleton
Osteoporosis
2018
6 引用 (Scopus)

A Comparative Assessment of Implant Site Viability in Humans and Rats

Chen, C. H., Pei, X., Tulu, U. S., Aghvami, M., Chen, C. T., Gaudillière, D., arioka, M., Maghazeh Moghim, M., Bahat, O., Kolinski, M., Crosby, T. R., Felderhoff, A., Brunski, J. B. & Helms, J. A., 4 1 2018, : : Journal of Dental Research. 97, 4, p. 451-459 9 p.

研究成果: ジャーナルへの寄稿記事

Osteotomy
Bone and Bones
Osteocytes
Osseointegration
Tooth Extraction
5 引用 (Scopus)

An osteopenic/osteoporotic phenotype delays alveolar bone repair

Chen, C. H., Wang, L., Serdar Tulu, U., arioka, M., Moghim, M. M., Salmon, B., Chen, C. T., Hoffmann, W., Gilgenbach, J., Brunski, J. B. & Helms, J. A., 7 1 2018, : : Bone. 112, p. 212-219 8 p.

研究成果: ジャーナルへの寄稿記事

Phenotype
Bone and Bones
Osteotomy
Osteogenesis
Tooth Socket
3 引用 (Scopus)

Bright multicolor labeling of neuronal circuits with fluorescent proteins and chemical tags

Sakaguchi, R., Leiwe, M. N. & Imai, T., 11 1 2018, : : eLife. 7, e40350.

研究成果: ジャーナルへの寄稿記事

Labeling
Fluorescence
Neurons
Networks (circuits)
Labels

In vivo two-photon imaging of the embryonic cortex reveals spontaneous ketamine-sensitive calcium activity

Yuryev, M., Andriichuk, L., Leiwe, M. N., Jokinen, V., Carabalona, A. & Rivera, C., 12 1 2018, : : Scientific reports. 8, 1, 16059.

研究成果: ジャーナルへの寄稿記事

Ketamine
Photons
Calcium
Cell Movement
Anesthesia
2017
7 引用 (Scopus)

2,5-Dimethylcelecoxib prevents pressure-induced left ventricular remodeling through GSK-3 activation

Fujita, A., Takahashi-Yanaga, F., Morimoto, S., Yoshihara, T., arioka, M., Igawa, K., Tomooka, K., Hoka, S. & Sasaguri, T., 2 1 2017, : : Hypertension Research. 40, 2, p. 130-139 10 p.

研究成果: ジャーナルへの寄稿記事

Glycogen Synthase Kinase 3
Ventricular Remodeling
Pressure
Constriction
Heart Failure
5 引用 (Scopus)
Glycogen Synthase Kinase 3
Cell proliferation
Cell Movement
Tumors
Melanoma
11 引用 (Scopus)

Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway

Egashira, I., Takahashi-Yanaga, F., Nishida, R., arioka, M., Igawa, K., Tomooka, K., Nakatsu, Y., Tsuzuki, T., Nakabeppu, Y., Kitazono, T. & Sasaguri, T., 1 1 2017, : : Cancer Science. 108, 1, p. 108-115 8 p.

研究成果: ジャーナルへの寄稿記事

Celecoxib
Intestinal Neoplasms
Catenins
Wnt Signaling Pathway
Growth
11 引用 (Scopus)

Celecoxib inhibits osteoblast maturation by suppressing the expression of Wnt target genes

Nagano, A., arioka, M., Takahashi-Yanaga, F., Matsuzaki, E. & Sasaguri, T., 1 1 2017, : : Journal of Pharmacological Sciences. 133, 1, p. 18-24 7 p.

研究成果: ジャーナルへの寄稿記事

Celecoxib
Osteoblasts
Wnt Signaling Pathway
Genes
Anti-Inflammatory Agents
2 引用 (Scopus)

Inorganic phosphate-induced impairment of osteoclast cell-cell fusion by the inhibition of AP-1-mediated DC-STAMP expression

arioka, M., Takahashi-Yanaga, F., Tatsumoto, N. & Sasaguri, T., 11 4 2017, : : Biochemical and Biophysical Research Communications. 493, 1, p. 9-13 5 p.

研究成果: ジャーナルへの寄稿記事

Cell Fusion
Transcription Factor AP-1
Osteoclasts
Osteogenesis
Dendritic Cells
6 引用 (Scopus)

Mechanosensory-Based Phase Coding of Odor Identity in the Olfactory Bulb

Iwata, R., Kiyonari, H. & Imai, T., 12 6 2017, : : Neuron. 96, 5, p. 1139-1152.e7

研究成果: ジャーナルへの寄稿記事

Olfactory Bulb
Olfactory Receptor Neurons
Smell
Masks
Odorants
2016
2 引用 (Scopus)

Distorted Coarse Axon Targeting and Reduced Dendrite Connectivity Underlie Dysosmia after Olfactory Axon Injury

Murai, A., Iwata, R., Fujimoto, S., Aihara, S., Tsuboi, A., Muroyama, Y., Saito, T., Nishizaki, K. & Imai, T., 10 28 2016, : : eNeuro. 3, 5

研究成果: ジャーナルへの寄稿記事

Olfactory Receptor Neurons
Olfaction Disorders
Dendrites
Axons
Wounds and Injuries
1 引用 (Scopus)

Geniculo-Cortical projection diversity revealed within the mouse visual thalamus

Leiwe, M. N., Hendry, A. C., Bard, A. D., Eglen, S. J., Lowe, A. S. & Thompson, I. D., 1 4 2016, : : PloS one. 11, 1, A80.

研究成果: ジャーナルへの寄稿記事

Geniculate Bodies
thalamus
Thalamus
Animals
mice

GSK-3β heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy

Mohamed, R. M. S. M., Morimoto, S., Ibrahim, I. A. A. E. H., Zhan, D. Y., Du, C. K., arioka, M., Yoshihara, T., Takahashi, F. & Sasaguri, T., 6 1 2016, : : American Journal of Physiology - Heart and Circulatory Physiology. 310, 11, p. H1808-H1815

研究成果: ジャーナルへの寄稿記事

Glycogen Synthase Kinase 3
Dilated Cardiomyopathy
Mutation
Heart Failure
Cardiac Myosins
6 引用 (Scopus)
Glycogen Synthase Kinase 3
Macrophages
Prostaglandins E
Dinoprostone
Monocytes
2 引用 (Scopus)

Inhibition of GSK-3β increases trabecular bone volume but not cortical bone volume in adenine-induced uremic mice with severe hyperparathyroidism

Tatsumoto, N., arioka, M., Yamada, S., Takahashi, F., Tokumoto, M., Tsuruya, K., Kitazono, T. & Sasaguri, T., 11 1 2016, : : Physiological Reports. 4, 21, e13010.

研究成果: ジャーナルへの寄稿記事

Glycogen Synthase Kinase 3
Hyperparathyroidism
Adenine
Chronic Renal Insufficiency
Lithium Chloride
67 引用 (Scopus)

Super-Resolution Mapping of Neuronal Circuitry With an Index-Optimized Clearing Agent

Ke, M. T., Nakai, Y., Fujimoto, S., Takayama, R., Yoshida, S., Kitajima, T. S., Sato, M. & Imai, T., 3 22 2016, : : Cell Reports. 14, 11, p. 2718-2732 15 p.

研究成果: ジャーナルへの寄稿記事

Tissue
Aberrations
Light scattering
Neurons
Microscopy
2015
8 引用 (Scopus)

Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo

Kubokura, N., Takahashi, F., arioka, M., Yoshihara, T., Igawa, K., Tomooka, K., Morimoto, S., Nakatsu, Y., Tsuzuki, T., Nakabeppu, Y., Matsumoto, T., Kitazono, T. & Sasaguri, T., 1 1 2015, : : Journal of Pharmacological Sciences. 127, 4, p. 446-455 10 p.

研究成果: ジャーナルへの寄稿記事

Growth
Neoplasms
Intestinal Neoplasms
Catenins
Dictyostelium
8 引用 (Scopus)

Stage-dependent benefits and risks of pimobendan in mice with genetic dilated cardiomyopathy and progressive heart failure

Nonaka, M., Morimoto, S., Murayama, T., Kurebayashi, N., Li, L., Wang, Y. Y., arioka, M., Yoshihara, T., Takahashi, F. & Sasaguri, T., 1 5 2015, : : British Journal of Pharmacology. 172, 9, p. 2369-2382 14 p.

研究成果: ジャーナルへの寄稿記事

Dilated Cardiomyopathy
Heart Failure
Sudden Cardiac Death
Sarcoplasmic Reticulum
pimobendan
2014
38 引用 (Scopus)

Acceleration of bone regeneration by local application of lithium: Wnt signal-mediated osteoblastogenesis and Wnt signal-independent suppression of osteoclastogenesis

arioka, M., Takahashi, F., Sasaki, M., Yoshihara, T., Morimoto, S., Hirata, M., Mori, Y. & Sasaguri, T., 8 15 2014, : : Biochemical Pharmacology. 90, 4, p. 397-405 9 p.

研究成果: ジャーナルへの寄稿記事

Glycogen Synthase Kinase 3
Bone Regeneration
Lithium
Osteogenesis
Bone
2013
21 引用 (Scopus)

Acceleration of bone development and regeneration through the Wnt/β-catenin signaling pathway in mice heterozygously deficient for GSK-3β

arioka, M., Takahashi, F., Sasaki, M., Yoshihara, T., Morimoto, S., Takashima, A., Mori, Y. & Sasaguri, T., 11 1 2013, : : Biochemical and Biophysical Research Communications. 440, 4, p. 677-682 6 p.

研究成果: ジャーナルへの寄稿記事

Glycogen Synthase Kinase 3
Catenins
Wnt Signaling Pathway
Bone Regeneration
Bone Development
403 引用 (Scopus)

SeeDB: A simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

Ke, M. T., Fujimoto, S. & Imai, T., 8 1 2013, : : Nature Neuroscience. 16, 8, p. 1154-1161 8 p.

研究成果: ジャーナルへの寄稿記事

Brain
Olfactory Bulb
Dendrites
Fluorescent Dyes
Photons
2012
6 引用 (Scopus)

Positional information in neural map development: Lessons from the olfactory system

Imai, T., 4 1 2012, : : Development Growth and Differentiation. 54, 3, p. 358-365 8 p.

研究成果: ジャーナルへの寄稿評論記事

Axons
Nervous System
Brain
2010
78 引用 (Scopus)

Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism

Hiramoto-Yamaki, N., Takeuchi, S., Ueda, S., Harada, K., Fujimoto, S., Negishi, M. & Katoh, H., 8 9 2010, : : Journal of Cell Biology. 190, 3, p. 461-477 17 p.

研究成果: ジャーナルへの寄稿記事

Cell Movement
Breast Neoplasms
Guanine Nucleotide Exchange Factors
Eph Family Receptors
Ephrins
2009
23 引用 (Scopus)

RhoG promotes neural progenitor cell proliferation in mouse cerebral cortex

Fujimoto, S., Negishi, M. & Katoh, H., 12 1 2009, : : Molecular biology of the cell. 20, 23, p. 4941-4950 10 p.

研究成果: ジャーナルへの寄稿記事

Cerebral Cortex
Stem Cells
Cell Proliferation
Bromodeoxyuridine
Phosphatidylinositol 3-Kinase
2008
39 引用 (Scopus)

Dock4 regulates dendritic development in hippocampal neurons

Ueda, S., Fujimoto, S., Hiramoto, K., Negishi, M. & Katoh, H., 12 8 2008, : : Journal of Neuroscience Research. 86, 14, p. 3052-3061 10 p.

研究成果: ジャーナルへの寄稿記事

Dendrites
Neurons
GTP Phosphohydrolase Activators
Growth
Activator Appliances
2003
38 引用 (Scopus)

Developmental elimination of ectopic projection sites for the transgenic OR gene that has lost zone specificity in the olfactory epithelium

Nakatani, H., Serizawa, S., Nakajima, M., Imai, T. & Sakano, H., 11 1 2003, : : European Journal of Neuroscience. 18, 9, p. 2425-2432 8 p.

研究成果: ジャーナルへの寄稿記事

Odorant Receptors
Olfactory Mucosa
Olfactory Bulb
Olfactory Receptor Neurons
Genes