循環器内科

研究成果 2000 2019

2019
5 引用 (Scopus)

Antithrombotic therapy for atrial fibrillation with stable coronary disease

the AFIRE Investigators, 9 19 2019, : : New England Journal of Medicine. 381, 12, p. 1103-1113 11 p.

研究成果: ジャーナルへの寄稿記事

Atrial Fibrillation
Coronary Disease
Coronary Artery Disease
Therapeutics
Confidence Intervals

Architecture of the Japan ischemic heart disease multimodal prospective data acquisition for precision treatment (J-IMPACT) system

Matoba, T., Kohro, T., Fujita, H., Nakayama, M., Kiyosue, A., Miyamoto, Y., Nishimura, K., Hashimoto, H., Antoku, Y., Nakashima, N., Ohe, K., Ogawa, H., Tsutsui, H. & Nagai, R., 1 1 2019, : : International heart journal. 60, 2, p. 264-270 7 p.

研究成果: ジャーナルへの寄稿記事

公開
Percutaneous Coronary Intervention
Myocardial Ischemia
Japan
Coronary Angiography
Information Systems

Clinical characteristics and prognostic factors in acute coronary syndrome patients complicated with cardiogenic shock in Japan: analysis from the Japanese Circulation Society Cardiovascular Shock Registry

Sakamoto, K., Matoba, T., Mohri, M., Ueki, Y., Tsujita, Y., Yamasaki, M., Tanaka, N., Hokama, Y., Fukutomi, M., Hashiba, K., Fukuhara, R., Suwa, S., Matsuura, H., Tachibana, E., Yonemoto, N. & Nagao, K., 8 1 2019, : : Heart and Vessels. 34, 8, p. 1241-1249 9 p.

研究成果: ジャーナルへの寄稿記事

Cardiogenic Shock
Acute Coronary Syndrome
Registries
Shock
Japan
Balloon Angioplasty
Pulmonary Hypertension
Lung
Therapeutics
ROC Curve
公開
Heart-Assist Devices
Thrombosis
Transplants
Architectural Accessibility
Heart Failure
3 引用 (Scopus)

Guidelines for the treatment of pulmonary hypertension (JCS 2017/JPCPHS 2017)

Japanese Circulation Society and the Japanese Pulmonary Circulation and Pulmonary Hypertension Society Joint Working Group, 4 2019, : : Circulation Journal. 83, 4, p. 842-945 104 p.

研究成果: ジャーナルへの寄稿記事

公開
Pulmonary Hypertension
Guidelines
1 引用 (Scopus)

Inhibition of TLR9-NF-κB-mediated sterile inflammation improves pressure overload-induced right ventricular dysfunction in rats

Yoshida, K., Abe, K., Ishikawa, M., Saku, K., Shinoda-Sakamoto, M., Ishikawa, T., Watanabe, T., Oka, M., Sunagawa, K. & Tsutsui, H., 3 1 2019, : : Cardiovascular research. 115, 3, p. 658-668 11 p.

研究成果: ジャーナルへの寄稿記事

Toll-Like Receptor 9
Right Ventricular Dysfunction
Pulmonary Artery
Inflammation
Pressure
1 引用 (Scopus)

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J. I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., 6 1 2019, : : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

研究成果: ジャーナルへの寄稿記事

公開
Myocardial Reperfusion Injury
Toll-Like Receptor 4
Reperfusion Injury
Nanoparticles
Myocardial Ischemia

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J-I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., 6 1 2019, : : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

研究成果: ジャーナルへの寄稿記事

Myocardial Reperfusion Injury
Toll-Like Receptor 4
Reperfusion Injury
Nanoparticles
Myocardial Ischemia
3 引用 (Scopus)

Peroxisome proliferator-activated receptor-gamma targeting nanomedicine promotes cardiac healing after acute myocardial infarction by skewing monocyte/macrophage polarization in preclinical animal models

Tokutome, M., Matoba, T., Nakano, Y., Okahara, A., Fujiwara, M., Koga, J. I., Nakano, K., Tsutsui, H. & Egashira, K., 2 1 2019, : : Cardiovascular research. 115, 2, p. 419-431 13 p.

研究成果: ジャーナルへの寄稿記事

pioglitazone
Nanomedicine
PPAR gamma
Monocytes
Animal Models
Coma
Registries
Shock
Japan
Out-of-Hospital Cardiac Arrest

Prognostic value of neurological status on hospital arrival for short-term outcome in patients with cardiovascular shock - Sub-analysis of the Japanese circulation society cardiovascular shock registry ―

Ueki, Y., Mohri, M., Matoba, T., Kadokami, T., Suwa, S., Yagi, T., Takahashi, H., Tanaka, N., Hokama, Y., Fukuhara, R., Onitsuka, K., Tachibana, E., Yonemoto, N. & Nagao, K., 1 1 2019, : : Circulation Journal. 83, 6, p. 1247-1253 7 p.

研究成果: ジャーナルへの寄稿記事

公開
Coma
Registries
Shock
Japan
Out-of-Hospital Cardiac Arrest
2 引用 (Scopus)

Proteinase-activated receptor 1 antagonism ameliorates experimental pulmonary hypertension

Kuwabara, Y., Tanaka-Ishikawa, M., Abe, K., Hirano, M., Hirooka, Y., Tsutsui, H., Sunagawa, K. & Hirano, K., 7 1 2019, : : Cardiovascular research. 115, 8, p. 1357-1368 12 p.

研究成果: ジャーナルへの寄稿記事

公開
PAR-1 Receptor
Pulmonary Hypertension
Monocrotaline
Pulmonary Artery
Right Ventricular Hypertrophy

Simple risk score to predict survival in acute decompensated heart failure: A2B score

Nakada, Y., Kawakami, R., Matsushima, S., Ide, T., Kanaoka, K., Ueda, T., Ishihara, S., Nishida, T., Onoue, K., Soeda, T., Okayama, S., Watanabe, M., Okura, H., Tsuchihashi-Makaya, M., Tsutsui, H. & Saito, Y., 1 1 2019, : : Circulation Journal. 83, 5, p. 1019-1024 6 p.

研究成果: ジャーナルへの寄稿記事

公開
Heart Failure
Survival
Patient Discharge
Brain Natriuretic Peptide
Hemoglobins

Suppressed baroreflex peripheral arc overwhelms augmented neural arc and incapacitates baroreflex function in rats with pulmonary arterial hypertension

Shinoda, M., Saku, K., Oga, Y., Tohyama, T., Nishikawa, T., Abe, K., Yoshida, K., Kuwabara, Y., Fujii, K., Ishikawa, T., Kishi, T., Sunagawa, K. & Tsutsui, H., 1 1 2019, : : Experimental Physiology.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Pulmonary Hypertension
Monocrotaline
Arterial Pressure
Pressure
Right Ventricular Dysfunction
Pulmonary Hypertension
Electrocardiography

Unexpected, but reasonable association between anderson-fabry disease and coronary vasospasm

Matoba, T., Nakano, Y. & Tsutsui, H., 2 2019, : : Circulation Journal. 83, 2, p. 283-284 2 p.

研究成果: ジャーナルへの寄稿記事

Coronary Vasospasm
Fabry Disease
Pulmonary Hypertension
Vascular Resistance
Anticoagulants
Incidence
2018
2 引用 (Scopus)

A pro-con debate: Current controversies in pah pathogenesis at the american thoracic society international conference in 2017

Kuebler, W. M., Nicolls, M. R., Olschewski, A., Abe, K., Rabinovitch, M., Stewart, D., Chan, S. Y., Morrell, N. W., Archer, S. L. & Spiekerkoetter, E., 10 2018, : : American Journal of Physiology - Lung Cellular and Molecular Physiology. 315, 4, p. L502-L516

研究成果: ジャーナルへの寄稿評論記事

Pulmonary Hypertension
Thorax
Bone Morphogenetic Protein Receptors
Bone Morphogenetic Protein 2
Immune System
3 引用 (Scopus)

Atrial fibrillation and ischemic events with rivaroxaban in patients with stable coronary artery disease (AFIRE): Protocol for a multicenter, prospective, randomized, open-label, parallel group study

Yasuda, S., Kaikita, K., Ogawa, H., Akao, M., Ako, J., Matoba, T., Nakamura, M., Miyauchi, K., Hagiwara, N., Kimura, K., Hirayama, A. & Matsui, K., 8 15 2018, : : International Journal of Cardiology. 265, p. 108-112 5 p.

研究成果: ジャーナルへの寄稿記事

Atrial Fibrillation
Coronary Artery Disease
Percutaneous Coronary Intervention
Anticoagulants
clopidogrel
2 引用 (Scopus)
Balloon Angioplasty
Pulmonary Hypertension
Hemodynamics
Lung
Angioplasty
12 引用 (Scopus)

Effectiveness and outcome of pulmonary arterial hypertension-specific therapy in japanese patients with pulmonary arterial hypertension

on behalf of the Japan PH Registry (JAPHR) Network, 1 1 2018, : : Circulation Journal. 82, 1, p. 275-282 8 p.

研究成果: ジャーナルへの寄稿記事

Pulmonary Hypertension
Registries
Japan
Hemodynamics
Therapeutics
3 引用 (Scopus)

Electrical Vagal Nerve Stimulation Ameliorates Pulmonary Vascular Remodeling and Improves Survival in Rats With Severe Pulmonary Arterial Hypertension

Yoshida, K., Saku, K., Kamada, K., Abe, K., Tanaka-Ishikawa, M., Tohyama, T., Nishikawa, T., Kishi, T., Sunagawa, K. & Tsutsui, H., 10 1 2018, : : JACC: Basic to Translational Science. 3, 5, p. 657-671 15 p.

研究成果: ジャーナルへの寄稿記事

Vagus Nerve Stimulation
Pulmonary Hypertension
Lung
Right Ventricular Function
Therapeutic Uses
12 引用 (Scopus)

Left Ventricular Mechanical Unloading by Total Support of Impella in Myocardial Infarction Reduces Infarct Size, Preserves Left Ventricular Function, and Prevents Subsequent Heart Failure in Dogs

Saku, K., Kakino, T., Arimura, T., Sunagawa, G., Nishikawa, T., sakamoto, T., Kishi, T., Tsutsui, H. & Sunagawa, K., 5 1 2018, : : Circulation. Heart failure. 11, 5, p. e004397

研究成果: ジャーナルへの寄稿記事

Left Ventricular Function
Reperfusion
Ischemia
Heart Failure
Myocardial Infarction
3 引用 (Scopus)

Lipid-Lowering Therapy with Ezetimibe Decreases Spontaneous Atherothrombotic Occlusions in a Rabbit Model of Plaque Erosion

Honda, K., Matoba, T., Antoku, Y., Koga, J. I., Ichi, I., Nakano, K., Tsutsui, H. & Egashira, K., 4 1 2018, : : Arteriosclerosis, thrombosis, and vascular biology. 38, 4, p. 757-771 15 p.

研究成果: ジャーナルへの寄稿記事

Rabbits
Lipids
Thromboplastin
Serum
Arteries
1 引用 (Scopus)
Monocrotaline
Pulmonary Hypertension
Intravenous Administration
Nanoparticles
Pulmonary Artery

Pulmonary arterial input impedance reflects the mechanical properties of pulmonary arterial remodeling in rats with pulmonary hypertension

Nishikawa, T., Saku, K., Kishi, T., Tohyama, T., Abe, K., Oga, Y., Arimura, T., sakamoto, T., Yoshida, K., Sunagawa, K. & Tsutsui, H., 11 1 2018, : : Life Sciences. 212, p. 225-232 8 p.

研究成果: ジャーナルへの寄稿記事

Electric Impedance
Pulmonary Hypertension
Compliance
Rats
Pulmonary Artery
3 引用 (Scopus)
Intravenous Administration
Nanoparticles
Pharmacokinetics
Placebos
Research Personnel
3 引用 (Scopus)

The impact of volume loading–induced low pressure baroreflex activation on arterial baroreflex-controlled sympathetic arterial pressure regulation in normal rats

Oga, Y., Saku, K., Nishikawa, T., Kishi, T., Tobushi, T., Hosokawa, K., Tohyama, T., Sakamoto, T., Sunagawa, K. & Tsutsui, H., 9 2018, : : Physiological Reports. 6, 19, e13887.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Arterial Pressure
Pressure
Central Venous Pressure
Carotid Sinus
1 引用 (Scopus)

Three nights leg thermal therapy could improve sleep quality in patients with chronic heart failure

Sawatari, H., Nishizaka, M. K., Miyazono, M., Ando, S. I., Inoue, S., Takemoto, M., sakamoto, T., Goto, D., Furumoto, T., Kinugawa, S., Hashiguchi, N., Rahmawati, A., Chishaki, H., Ohkusa, T., Magota, C., Tsutsui, H. & Chishaki, A., 2 1 2018, : : Heart and Vessels. 33, 2, p. 155-162 8 p.

研究成果: ジャーナルへの寄稿記事

Leg
Sleep
Heart Failure
Hot Temperature
Therapeutics
2017
Balloon Angioplasty
Pulmonary Hypertension
Lung
Single Photon Emission Computed Tomography Computed Tomography

Anti-inflammatory Nanomedicine for Cardiovascular Disease

Katsuki, S., Matoba, T., Koga, J-I., Nakano, K. & Egashira, K., 2017, : : Frontiers in cardiovascular medicine. 4, p. 87

研究成果: ジャーナルへの寄稿評論記事

Nanomedicine
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Nanotechnology
Anti-Inflammatory Agents
Cardiovascular Diseases
20 引用 (Scopus)
Balloon Angioplasty
Pulmonary Hypertension
Stroke Volume
Lung
Magnetic Resonance Imaging
2 引用 (Scopus)

Carotid body denervation markedly improves survival in rats with hypertensive heart failure

Fujii, K., Saku, K., Kishi, T., Oga, Y., Tohyama, T., Nishikawa, T., Sakamoto, T., Ikeda, M., Ide, T., Tsutsui, H. & Sunagawa, K., 1 1 2017, : : American Journal of Hypertension. 30, 8, p. 791-798 8 p.

研究成果: ジャーナルへの寄稿記事

Carotid Body
Denervation
Heart Failure
Survival
Natriuresis
3 引用 (Scopus)

Central chemoreflex activation induces sympatho-excitation without altering static or dynamic baroreflex function in normal rats

Saku, K., Tohyama, T., Shinoda, M., Kishi, T., Hosokawa, K., Nishikawa, T., Oga, Y., Sakamoto, T., Tsutsui, H., Miyamoto, T. & Sunagawa, K., 9 12 2017, : : Physiological Reports. 5, 17, e13406.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Pressure
Arterial Pressure
Carotid Sinus
Sympathetic Ganglia
1 引用 (Scopus)
Balloon Angioplasty
Lung Injury
Pulmonary Hypertension
Lung
3 引用 (Scopus)
Balloon Angioplasty
Pulmonary Hypertension
Pulmonary Artery
Lung
Magnetic Resonance Imaging
11 引用 (Scopus)

Ezetimibe in combination with statins ameliorates endothelial dysfunction in coronary arteries after stenting: the CuVIC trial (effect of cholesterol absorption inhibitor usage on target vessel dysfunction after coronary stenting), a multicenter randomized controlled trial

Takase, S., Matoba, T., Nakashiro, S., Mukai, Y., Inoue, S., Oi, K., Higo, T., Katsuki, S., Takemoto, M., Suematsu, N., Eshima, K., Miyata, K., Yamamoto, M., Usui, M., Sadamatsu, K., Satoh, S., Kadokami, T., Hironaga, K., Ichi, I., Todaka, K. および3人, Kishimoto, J., Egashira, K. & Sunagawa, K., 2 2017, : : Arteriosclerosis, thrombosis, and vascular biology. 37, 2, p. 350-358 9 p.

研究成果: ジャーナルへの寄稿記事

Anticholesteremic Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Coronary Vessels
Randomized Controlled Trials
Coronary Angiography
2 引用 (Scopus)
High Cardiac Output
Stroke Volume
Heart Failure
Blood Pressure
Cardiac Output
2 引用 (Scopus)

Inhibition of nitric oxide synthase unmasks vigorous vasoconstriction in established pulmonary arterial hypertension

Tanaka, M., Abe, K., Oka, M., Saku, K., Yoshida, K., Ishikawa, T., McMurtry, I. F., Sunagawa, K., Hoka, S. & Tsutsui, H., 12 2017, : : Physiological Reports. 5, 23, e13537.

研究成果: ジャーナルへの寄稿記事

Vasoconstriction
Pulmonary Hypertension
Nitric Oxide Synthase
Nitric Oxide
Ventricular Pressure
11 引用 (Scopus)

Intravenous electrical vagal nerve stimulation prior to coronary reperfusion in a canine ischemia-reperfusion model markedly reduces infarct size and prevents subsequent heart failure

Arimura, T., Saku, K., Kakino, T., Nishikawa, T., Tohyama, T., sakamoto, T., Sakamoto, K., Kishi, T., Ide, T. & Sunagawa, K., 1 15 2017, : : International Journal of Cardiology. 227, p. 704-710 7 p.

研究成果: ジャーナルへの寄稿記事

Vagus Nerve Stimulation
Myocardial Reperfusion
Reperfusion
Canidae
Ischemia
4 引用 (Scopus)

Ischemic or Nonischemic Functional Mitral Regurgitation and Outcomes in Patients With Acute Decompensated Heart Failure With Preserved or Reduced Ejection Fraction

Kajimoto, K., Minami, Y., Otsubo, S., Sato, N., Sato, N., Asai, K., Munakata, R., Aokage, T., Yoshida, A., Minami, Y., Yumino, D., Mizuno, M., Kawada, E., Yoshida, K., Ozaki, Y., Kogure, T., Haruki, S., Mizuno, M., Kajimoto, K., Nakao, K. および171人, Sawamura, T., Nuki, T., Ishiki, R., Yokota, S., Fujinaga, H., Yamamoto, T., Harada, K., Saito, A., Kageyama, N., Okumura, T., Hata, N., Murai, K., Nozaki, A., Kawanaka, H., Tanabe, J., Sato, Y., Ishii, K., Oiwa, H., Matsumoto, T., Yoshida, D., Kato, N., Suzuki, H., Shimizu, N., Keida, T., Fujita, M., Nakamura, K., Chinen, T., Meguro, K., Kikuchi, T., Nishikido, T., Nakata, M., Yamashita, T., Nakata, M., Hirono, A., Mitsudo, K., Kadota, K., Makita, N., Watanabe, N., Kawabata, M., Fujii, K., Okuda, S., Kobayashi, S., Moriuchi, I., Mizuno, K. O., Osato, K., Murakami, T., Shimada, Y., Misawa, K., Kokado, H., Fujita, T., Fukuoka, Y., Takabatake, S., Takata, Y., Miyagi, M., Tanaka, N., Yamashina, A., Sudo, S., Shimamura, K., Nagashima, M., Kaneda, T., Ueda, K., Kato, H., Higashikata, T., Fujimori, K., Kobayashi, H., Fujii, S., Yagi, M., Ozaki, Y., Takaki, J., Yamashita, E., Toyama, T., Hirata, T., Kamisihima, K., Oka, T., Komatsu, R., Itoh, A., Naruko, T., Abe, Y., Nakagawa, E., Furukawa, A., Kinou, N., Uematsu, S., Tabuchi, I., Imai, T., Sakamoto, T., Todaka, K., Koide, Y., Maemura, K., Yoshioka, K., Yoshihisa, A., Sato, T., Takeishi, Y., Ebina, T., Kimura, K., Konishi, M., Kato, M., Kinugasa, Y., Ishida, K., Sugihara, S., Yanagihara, K., Takeuchi, T., Okada, M., Hasebe, N., Sakai, T., Asano, T., Minoura, Y., Toshida, T., Sato, T., Yokota, Y., Kondo, S., Sakata, Y., Komuro, I., Otsu, K., Yamashita, S., Asano, Y., Yoshida, A., Kajimoto, K., Kashiwase, K., Ueda, Y., Kondo, T., Kawaguchi, K., Sawamura, A., Saito, T., Higa, T., Noguchi, H., Yanagita, Y., Nakamura, K., Komaki, T., Muramatsu, T., Koizumi, T., Nakajima, Y., Kikutani, T., Ikeda, Y., Tamaki, T., Funada, S., Ogawa, H., Sakuragawa, K., Kohsaka, S., Ando, S. I., Kadokami, T., Ishida, E., Ide, K., Sotomi, Y., Higuchi, Y., Uehara, M., Goto, T., Ohte, N., Miura, M., Shiba, N., Nochioka, K., Shimokawa, H., Ishihara, S., Koga, T., Fujishima, S., Kaseda, S., Haga, Y., Kida, K., Kamisihima, K., Nakamura, M., Sunagawa, O., Miyara, T., Taba, Y., Touma, T., Shinjo, O., Nishimura, Y., Kario, K., Shimizu, H., Uchida, T., Amitani, K. I., Sato, N. & Shimada, K., 9 1 2017, : : American Journal of Cardiology. 120, 5, p. 809-816 8 p.

研究成果: ジャーナルへの寄稿記事

Mitral Valve Insufficiency
Heart Failure
Confidence Intervals
Registries
Cause of Death
17 引用 (Scopus)
Ventricular Remodeling
Nanoparticles
Monocytes
Macrophages
Myocardial Infarction
14 引用 (Scopus)

Nanoparticle-mediated drug delivery system for atherosclerotic cardiovascular disease

Matoba, T., Koga, J. I., Nakano, K., Egashira, K. & Tsutsui, H., 9 1 2017, : : Journal of Cardiology. 70, 3, p. 206-211 6 p.

研究成果: ジャーナルへの寄稿評論記事

Drug Delivery Systems
Nanoparticles
Cardiovascular Diseases
pioglitazone
Monocytes
2 引用 (Scopus)

Pioglitazone improves whole-body aerobic capacity and skeletal muscle energy metabolism in patients with metabolic syndrome

Yokota, T., Kinugawa, S., Hirabayashi, K., Suga, T., Takada, S., Omokawa, M., Kadoguchi, T., Takahashi, M., Fukushima, A., Matsushima, S., Yamato, M., Okita, K. & Tsutsui, H., 7 2017, : : Journal of Diabetes Investigation. 8, 4, p. 535-541 7 p.

研究成果: ジャーナルへの寄稿記事

pioglitazone
Energy Metabolism
Skeletal Muscle
Exercise
Anaerobic Threshold
3 引用 (Scopus)

Prediction of hemodynamics under left ventricular assist device

Kakino, T., Saku, K., Sakamoto, T., Sakamoto, K., Akashi, T., Ikeda, M., Ide, T., Kishi, T., Tsutsui, H. & Sunagawa, K., 1 1 2017, : : American Journal of Physiology - Heart and Circulatory Physiology. 312, 1, p. H80-H88

研究成果: ジャーナルへの寄稿記事

Heart-Assist Devices
Hemodynamics
Cardiac Output
Atrial Pressure
Right Ventricular Function
1 引用 (Scopus)
Chronic Renal Insufficiency
Pulmonary Hypertension
Renal Dialysis
Vascular Resistance
Arterial Pressure
4 引用 (Scopus)
Technetium Tc 99m Aggregated Albumin
Fractals
Balloon Angioplasty
Single-Photon Emission-Computed Tomography
Pulmonary Hypertension
1 引用 (Scopus)
hypertension
phase contrast
arteries
Pulmonary Hypertension
Pulmonary Artery