遺伝子・細胞療法部

研究成果

2020

Pathophysiology of chronic lymphocytic leukemia and human B1 cell development

Kikushige, Y., 5 1 2020, : : International journal of hematology. 111, 5, p. 634-641 8 p.

研究成果: Contribution to journalReview article

Tyrosine kinase inhibitors induce alternative spliced BCR-ABLIns35bp variant via inhibition of RNA polymerase II on genomic BCR-ABL

Yuda, J., Odawara, J., Minami, M., Muta, T., Kohno, K., Tanimoto, K., Eto, T., Shima, T., Kikushige, Y., Kato, K., Takenaka, K., Iwasaki, H., Minami, Y., Ohkawa, Y., Akashi, K. & Miyamoto, T., 7 1 2020, : : Cancer Science. 111, 7, p. 2361-2373 13 p.

研究成果: Contribution to journalArticle

公開
2019

Anti-GPRC5D/CD3 bispecific T-cell-redirecting antibody for the treatment of multiple myeloma

Kodama, T., Kochi, Y., Nakai, W., Mizuno, H., Baba, T., Habu, K., Sawada, N., Tsunoda, H., Shima, T., Miyawaki, K., Kikushige, Y., Mori, Y., Miyamoto, T., Maeda, T. & Akashi, K., 2019, : : Molecular cancer therapeutics. 18, 9, p. 1555-1564 10 p.

研究成果: Contribution to journalArticle

7 引用 (Scopus)

CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines

Takaki-Kuwahara, A., Arinobu, Y., Miyawaki, K., Yamada, H., Tsuzuki, H., Irino, K., Ayano, M., Kimoto, Y., Mitoma, H., Akahoshi, M., Tsukamoto, H., Horiuchi, T., Niiro, H. & Akashi, K., 8 30 2019, : : Arthritis Research and Therapy. 21, 1, 198.

研究成果: Contribution to journalArticle

公開
3 引用 (Scopus)

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth

Oshima, T., Niwa, Y., Kuwata, K., Srivastava, A., Hyoda, T., Tsuchiya, Y., Kumagai, M., Tsuyuguchi, M., Tamaru, T., Sugiyama, A., Ono, N., Zolboot, N., Aikawa, Y., Oishi, S., Nonami, A., Arai, F., Hagihara, S., Yamaguchi, J., Tama, F., Kunisaki, Y. および6人, Yagita, K., Ikeda, M., Kinoshita, T., Kay, S. A., Itami, K. & Hirota, T., 1 23 2019, : : Science Advances. 5, 1, eaau9060.

研究成果: Contribution to journalArticle

公開
17 引用 (Scopus)

Clinicopathological features of HCV-positive splenic diffuse large B cell lymphoma

Shimono, J., Miyoshi, H., Arakawa, F., Yamada, K., Sugio, T., Miyawaki, K., Eto, T., Miyagishima, T., Kato, K., Nagafuji, K., Akashi, K., Teshima, T. & Ohshima, K., 5 1 2019, : : Annals of Hematology. 98, 5, p. 1197-1207 11 p.

研究成果: Contribution to journalArticle

Dedifferentiation process driven by TGF-beta signaling enhances stem cell properties in human colorectal cancer

Nakano, M., Kikushige, Y., Miyawaki, K., Kunisaki, Y., Mizuno, S., Takenaka, K., Tamura, S., Okumura, Y., Ito, M., Ariyama, H., Kusaba, H., Nakamura, M., Maeda, T., Baba, E. & Akashi, K., 2 7 2019, : : Oncogene. 38, 6, p. 780-793 14 p.

研究成果: Contribution to journalArticle

18 引用 (Scopus)

DrugThatGene: Integrative analysis to streamline the identification of druggable genes, pathways and protein complexes from CRISPR screens

Canver, M. C., Bauer, D. E., Maeda, T. & Pinello, L., 1 1 2019, : : Bioinformatics. 35, 11, p. 1981-1984 4 p., bty913.

研究成果: Contribution to journalArticle

Molecular pathogenesis of disease progression in MLL-rearranged AML

Kotani, S., Yoda, A., Kon, A., Kataoka, K., Ochi, Y., Shiozawa, Y., Hirsch, C., Takeda, J., Ueno, H., Yoshizato, T., Yoshida, K., Nakagawa, M. M., Nannya, Y., Kakiuchi, N., Yamauchi, T., Aoki, K., Shiraishi, Y., Miyano, S., Maeda, T., Maciejewski, J. P. および3人, Takaori-Kondo, A., Ogawa, S. & Makishima, H., 3 1 2019, : : Leukemia. 33, 3, p. 612-624 13 p.

研究成果: Contribution to journalArticle

6 引用 (Scopus)

Pericytes in bone marrow

Kunisaki, Y., 1 1 2019, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 101-114 14 p. (Advances in Experimental Medicine and Biology; 巻数 1122).

研究成果: Chapter in Book/Report/Conference proceedingChapter

4 引用 (Scopus)

Previous exposure to bortezomib is linked to a lower risk of engraftment syndrome after autologous hematopoietic stem cell transplantation

Mori, Y., Yoshimoto, G., Yuda, J. I., Hayashi, M., Odawara, J., Kuriyama, T., Sugio, T., Miyawaki, K., Kamezaki, K., Kato, K., Takenaka, K., Iwasaki, H., Maeda, T., Miyamoto, T. & Akashi, K., 1 2 2019, : : Leukemia and Lymphoma. 60, 1, p. 271-273 3 p.

研究成果: Contribution to journalLetter

1 引用 (Scopus)

Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis

Sher, F., Hossain, M., Seruggia, D., Schoonenberg, V. A. C., Yao, Q., Cifani, P., Dassama, L. M. K., Cole, M. A., Ren, C., Vinjamur, D. S., Macias-Trevino, C., Luk, K., McGuckin, C., Schupp, P. G., Canver, M. C., Kurita, R., Nakamura, Y., Fujiwara, Y., Wolfe, S. A., Pinello, L. および4人, Maeda, T., Kentsis, A., Orkin, S. H. & Bauer, D. E., 7 1 2019, : : Nature genetics. 51, 7, p. 1149-1159 11 p.

研究成果: Contribution to journalArticle

5 引用 (Scopus)

Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis

Kidoya, H., Muramatsu, F., Shimamura, T., Jia, W., Satoh, T., Hayashi, Y., Naito, H., Kunisaki, Y., Arai, F., Seki, M., Suzuki, Y., Osawa, T., Akira, S. & Takakura, N., 12 1 2019, : : Nature communications. 10, 1, 1072.

研究成果: Contribution to journalArticle

公開
2 引用 (Scopus)

Successful rescue transplantation with desensitization procedure after primary graft failure due to donor-specific antibody

Minami, M., Matsushima, T., Mori, Y., Ishihara, D., Jinnnouchi, F., Takenaka, K., Henzan, T., Yoshimoto, G., Numata, A., Kato, K., Maeda, T., Miyamoto, T. & Akashi, K., 8 1 2019, : : Bone Marrow Transplantation. 54, 8, p. 1374-1376 3 p.

研究成果: Contribution to journalLetter

2018

Analysis of GNA13 Protein in Follicular Lymphoma and its Association with Poor Prognosis

Shimono, J., Miyoshi, H., Yoshida, N., Kato, T., Sato, K., Sugio, T., Miyawaki, K., Kurita, D., Sasaki, Y., Kawamoto, K., Imaizumi, Y., Kato, K., Nagafuji, K., Akashi, K., Seto, M., Teshima, T. & Ohshima, K., 11 1 2018, : : American Journal of Surgical Pathology. 42, 11, p. 1466-1471 6 p.

研究成果: Contribution to journalArticle

2 引用 (Scopus)

CRISPRO: Identification of functional protein coding sequences based on genome editing dense mutagenesis Jin-Soo Kim

Schoonenberg, V. A. C., Cole, M. A., Yao, Q., MacIas-Treviño, C., Sher, F., Schupp, P. G., Canver, M. C., Maeda, T., Pinello, L. & Bauer, D. E., 10 19 2018, : : Genome biology. 19, 1, 169.

研究成果: Contribution to journalArticle

6 引用 (Scopus)

Epithelial-mesenchymal transition is activated in CD44-positive malignant ascites tumor cells of gastrointestinal cancer

Nakano, M., Ito, M., Tanaka, R., Ariyama, H., Mitsugi, K., Makiyama, A., Uchino, K., Esaki, T., Tsuruta, N., Hanamura, F., Yamaguchi, K., Okumura, Y., Sagara, K., Takayoshi, K., Nio, K., Tsuchihashi, K., Tamura, S., Shimokawa, H., Arita, S., Miyawaki, K. および3人, Kusaba, H., Akashi, K. & Baba, E., 11 2018, : : Cancer Science. 109, 11, p. 3461-3470 10 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

Expression of PD-1 and PD-L1 on cytotoxic T lymphocytes and immune deficiency in a patient with adult T cell leukemia/lymphoma

Yanagihara, T., Ikematsu, Y., Kato, K., Yonekawa, A., Ideishi, S., Tochigi, T., Sugio, T., Miyawaki, K., Tanaka, K., Harada, E., Hamada, N. & Nakanishi, Y., 2 1 2018, : : Annals of Hematology. 97, 2, p. 359-360 2 p.

研究成果: Contribution to journalLetter

1 引用 (Scopus)

Gastrointestinal Graft-versus-Host Disease Is a Risk Factor for Postengraftment Bloodstream Infection in Allogeneic Hematopoietic Stem Cell Transplant Recipients

Mori, Y., Yoshimoto, G., Nishida, R., Sugio, T., Miyawaki, K., Shima, T., Nagasaki, Y., Miyake, N., Harada, Y., Kunisaki, Y., Kamezaki, K., Numata, A., Kato, K., Shiratsuchi, M., Maeda, T., Takenaka, K., Iwasaki, H., Shimono, N., Akashi, K. & Miyamoto, T., 11 2018, : : Biology of Blood and Marrow Transplantation. 24, 11, p. 2302-2309 8 p.

研究成果: Contribution to journalArticle

4 引用 (Scopus)

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

Yamauchi, T., Masuda, T., Canver, M. C., Seiler, M., Semba, Y., Shboul, M., Al-Raqad, M., Maeda, M., Schoonenberg, V. A. C., Cole, M. A., Macias-Trevino, C., Ishikawa, Y., Yao, Q., Nakano, M., Arai, F., Orkin, S. H., Reversade, B., Buonamici, S., Pinello, L., Akashi, K. および2人, Bauer, D. E. & Maeda, T., 3 12 2018, : : Cancer Cell. 33, 3, p. 386-400.e5

研究成果: Contribution to journalArticle

24 引用 (Scopus)

Hepatitis C virus infection is an independent prognostic factor in follicular lymphoma

Shimono, J., Miyoshi, H., Kato, T., Sugio, T., Miyawaki, K., Kamimura, T., Miyagishima, T., Eto, T., Imaizumi, Y., Kato, K., Nagafuji, K., Akashi, K., Seto, M., Teshima, T. & Ohshima, K., 2018, : : Oncotarget. 9, 2, p. 1717-1725 9 p.

研究成果: Contribution to journalArticle

3 引用 (Scopus)
2 引用 (Scopus)

Microenvironmental immune cell signatures dictate clinical outcomes for PTCL-NOS

Sugio, T., Miyawaki, K., Kato, K., Sasaki, K., Yamada, K., Iqbal, J., Miyamoto, T., Ohshima, K., Maeda, T., Miyoshi, H. & Akashi, K., 9 11 2018, : : Blood Advances. 2, 17, p. 2242-2252 11 p.

研究成果: Contribution to journalArticle

6 引用 (Scopus)

Successful treatment of Ph ALL with hematopoietic stem cell transplantation from the same HLA-haploidentical related donor of previous liver transplantation

Sasaki, K., Mori, Y., Yoshimoto, G., Sakoda, T., Kato, K., Inadomi, K., Kamezaki, K., Takenaka, K., Iwasaki, H., Maeda, T., Miyamoto, T. & Akashi, K., 8 3 2018, : : Leukemia and Lymphoma. 59, 8, p. 2005-2007 3 p.

研究成果: Contribution to journalEditorial

1 引用 (Scopus)
2017

Comparison between antiemetic effects of palonosetron and granisetron on chemotherapy-induced nausea and vomiting in Japanese patients treated with R-CHOP

Uchida, M., Mori, Y., Nakamura, T., Kato, K., Kamezaki, K., Takenaka, K., Shiratsuchi, M., Kadoyama, K., Miyamoto, T. & Akashi, K., 2017, : : Biological and Pharmaceutical Bulletin. 40, 9, p. 1499-1505 7 p.

研究成果: Contribution to journalArticle

5 引用 (Scopus)

Composite lymphoma of peripheral T-cell lymphoma and Hodgkin lymphoma, mixed cellularity type; pathological and molecular analysis

Ichikawa, A., Miyoshi, H., Yamauchi, T., Arakawa, F., Kawano, R., Muta, H., Sugita, Y., Akashi, K. & Ohshima, K., 4 1 2017, : : Pathology International. 67, 4, p. 194-201 8 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

Donor Lymphocyte Infusion for Relapsed Hematological Malignancies after Unrelated Allogeneic Bone Marrow Transplantation Facilitated by the Japan Marrow Donor Program

Medical Committee of Japan Marrow Donor Program, Japanese Data Center for Hematopoietic Cell Transplantation, 6 2017, : : Biology of Blood and Marrow Transplantation. 23, 6, p. 938-944 7 p.

研究成果: Contribution to journalArticle

21 引用 (Scopus)
9 引用 (Scopus)

Erythropoietin signaling regulates heme biosynthesis

Chung, J., Wittig, J. G., Ghamari, A., Maeda, M., Dailey, T. A., Bergonia, H., Kafina, M. D., Coughlin, E. E., Minogue, C. E., Hebert, A. S., Li, L., Kaplan, J., Lodish, H. F., Bauer, D. E., Orkin, S. H., Cantor, A. B., Maeda, T., Phillips, J. D., Coon, J. J., Pagliarini, D. J. および2人, Dailey, H. A. & Paw, B. H., 5 29 2017, : : eLife. 6, e24767.

研究成果: Contribution to journalArticle

10 引用 (Scopus)

Identification of unipotent megakaryocyte progenitors in human hematopoiesis

Miyawaki, K., Iwasaki, H., Jiromaru, T., Kusumoto, H., Yurino, A., Sugio, T., Uehara, Y., Odawara, J., Daitoku, S., Kunisaki, Y., Mori, Y., Arinobu, Y., Tsuzuki, H., Kikushige, Y., Iino, T., Kato, K., Takenaka, K., Miyamoto, T., Maeda, T. & Akashi, K., 6 22 2017, : : Blood. 129, 25, p. 3332-3343 12 p.

研究成果: Contribution to journalArticle

21 引用 (Scopus)

Mobilization of human immature hematopoietic progenitors through combinatory use of bortezomib and immunomodulatory drugs

Tochigi, T., Aoki, T., Kikushige, Y., Kamimura, T., Ito, Y., Shima, T., Yamauchi, T., Mori, Y., Yoshimoto, G., Kamezaki, K., Kato, K., Takenaka, K., Iwasaki, H., Akashi, K. & Miyamoto, T., 4 1 2017, : : International journal of hematology. 105, 4, p. 423-432 10 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

Most T790M mutations are present on the same EGFR allele as activating mutations in patients with non–small cell lung cancer

Hidaka, N., Iwama, E., Kubo, N., Harada, T., Miyawaki, K., Tanaka, K., Okamoto, I., Baba, E., Akashi, K., Sasaki, H. & Nakanishi, Y., 6 1 2017, : : Lung Cancer. 108, p. 75-82 8 p.

研究成果: Contribution to journalArticle

21 引用 (Scopus)

Recurrent subcutaneous sweet’s disease in a myelofibrosis patient treated with ruxolitinib before allogeneic stem cell transplantation

Sakoda, T., Kanamitsu, Y., Mori, Y., Sasaki, K., Yonemitsu, E., Nagae, K., Yoshimoto, G., Kamezaki, K., Kato, K., Takenaka, K., Miyamoto, T., Furue, M., Iwasaki, H. & Akashi, K., 1 1 2017, : : Internal Medicine. 56, 18, p. 2481-2485 5 p.

研究成果: Contribution to journalArticle

3 引用 (Scopus)

The simultaneous inhibition of the mTOR and MAPK pathways with Gnetin-C induces apoptosis in acute myeloid leukemia

Espinoza, J. L., Elbadry, M. I., Taniwaki, M., Harada, K., Trung, L. Q., Nakagawa, N., Takami, A., Ishiyama, K., Yamauchi, T., Takenaka, K. & Nakao, S., 8 1 2017, : : Cancer Letters. 400, p. 127-136 10 p.

研究成果: Contribution to journalArticle

10 引用 (Scopus)
2016

Allogeneic unrelated bone marrow transplantation from older donors results in worse prognosis in recipients with aplastic anemia

Japan Society for Hematopoietic Cell Transplantation, 4 30 2016, : : Haematologica. 101, 5, p. 644-652 9 p.

研究成果: Contribution to journalArticle

10 引用 (Scopus)

Ascites retention during mogamulizumab treatment in a patient with adult T-cell leukemia/lymphoma

Shima, T., Kamezaki, K., Higashioka, K., Takashima, S., Yoshimoto, G., Kato, K., Muta, T., Takenaka, K., Iwasaki, H., Miyamoto, T. & Akashi, K., 1 1 2016, : : Internal Medicine. 55, 13, p. 1793-1796 4 p.

研究成果: Contribution to journalArticle

Calreticulin mutation does not contribute to disease progression in essential thrombocythemia by inhibiting phagocytosis

Daitoku, S., Takenaka, K., Yamauchi, T., Yurino, A., Jinnouchi, F., Nunomura, T., Eto, T., Kamimura, T., Higuchi, M., Harada, N., Saito, N., Miyamoto, T., Iwasaki, H. & Akashi, K., 9 1 2016, : : Experimental Hematology. 44, 9, p. 817-825.e3

研究成果: Contribution to journalArticle

8 引用 (Scopus)

Cord blood transplantation following reduced-intensity conditioning for adult-onset inherited hemophagocytic lymphohistiocytosis

Kuriyama, T., Kato, K., Sakamoto, K., Hayashi, M., Takashima, S., Mori, Y., Takenaka, K., Iwasaki, H., Teshima, T., Harada, N., Nagafuji, K., Miyamoto, T. & Akashi, K., 3 15 2016, : : Internal Medicine. 55, 6, p. 667-671 5 p.

研究成果: Contribution to journalArticle

1 引用 (Scopus)

Enhanced Reconstitution of Human Erythropoiesis and Thrombopoiesis in an Immunodeficient Mouse Model with KitWv Mutations

Yurino, A., Takenaka, K., Yamauchi, T., Nunomura, T., Uehara, Y., Jinnouchi, F., Miyawaki, K., Kikushige, Y., Kato, K., Miyamoto, T., Iwasaki, H., Kunisaki, Y. & Akashi, K., 9 13 2016, : : Stem Cell Reports. 7, 3, p. 425-438 14 p.

研究成果: Contribution to journalArticle

11 引用 (Scopus)

Mogamulizumab Treatment Prior to Allogeneic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-versus-Host Disease

Sugio, T., Kato, K., Aoki, T., Ohta, T., Saito, N., Yoshida, S., Kawano, I., Henzan, H., Kadowaki, M., Takase, K., Muta, T., Miyawaki, K., Yamauchi, T., Shima, T., Takashima, S., Mori, Y., Yoshimoto, G., Kamezaki, K., Takenaka, K., Iwasaki, H. および6人, Ogawa, R., Ohno, Y., Eto, T., Kamimura, T., Miyamoto, T. & Akashi, K., 9 1 2016, : : Biology of Blood and Marrow Transplantation. 22, 9, p. 1608-1614 7 p.

研究成果: Contribution to journalArticle

25 引用 (Scopus)

Splenic irradiation provides transient palliation for symptomatic splenomegaly associated with primary myelofibrosis: a report on 14 patients

Kitanaka, A., Takenaka, K., Shide, K., Miyamoto, T., Kondo, T., Ozawa, K., Kurokawa, M., Akashi, K. & Shimoda, K., 4 1 2016, : : International journal of hematology. 103, 4, p. 423-428 6 p.

研究成果: Contribution to journalArticle

5 引用 (Scopus)
2015

A multinational, open-label, phase 2 study of ruxolitinib in Asian patients with myelofibrosis: Japanese subset analysis

Oritani, K., Okamoto, S., Tauchi, T., Saito, S., Ohishi, K., Handa, H., Takenaka, K., Gopalakrishna, P., Amagasaki, T., Ito, K. & Akashi, K., 3 6 2015, : : International journal of hematology. 101, 3, p. 295-304 10 p.

研究成果: Contribution to journalArticle

13 引用 (Scopus)

A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression

Kikushige, Y., Miyamoto, T., Yuda, J., Jabbarzadeh-Tabrizi, S., Shima, T., Takayanagi, S. I., Niiro, H., Yurino, A., Miyawaki, K., Takenaka, K., Iwasaki, H. & Akashi, K., 9 3 2015, : : Cell stem cell. 17, 3, p. 341-352 12 p., 1815.

研究成果: Contribution to journalArticle

65 引用 (Scopus)

CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: Redefinition of murine common myeloid progenitor

Miyawaki, K., Arinobu, Y., Iwasaki, H., Kohno, K., Tsuzuki, H., Iino, T., Shima, T., Kikushige, Y., Takenaka, K., Miyamoto, T. & Akashi, K., 3 1 2015, : : STEM CELLS. 33, 3, p. 976-987 12 p.

研究成果: Contribution to journalArticle

28 引用 (Scopus)

Cytomegalovirus Reactivation after Allogeneic Hematopoietic Stem Cell Transplantation is Associated with a Reduced Risk of Relapse in Patients with Acute Myeloid Leukemia Who Survived to Day 100 after Transplantation: The Japan Society for Hematopoietic Cell Transplantation Transplantation-related Complication Working Group

Takenaka, K., Nishida, T., Asano-Mori, Y., Oshima, K., Ohashi, K., Mori, T., Kanamori, H., Miyamura, K., Kato, C., Kobayashi, N., Uchida, N., Nakamae, H., Ichinohe, T., Morishima, Y., Suzuki, R., Yamaguchi, T. & Fukuda, T., 11 2015, : : Biology of Blood and Marrow Transplantation. 21, 11, p. 2008-2016 9 p.

研究成果: Contribution to journalArticle

65 引用 (Scopus)
1 引用 (Scopus)

Efficacy and safety of ruxolitinib in Asian patients with myelofibrosis

Jung, C. W., Shih, L. Y., Xiao, Z., Jie, J., Hou, H. A., Du, X., Wang, M. C., Park, S., Eom, K. S., Oritani, K., Okamoto, S., Tauchi, T., Kim, J. S., Zhou, D., Saito, S., Li, J., Handa, H., Jianyong, L., Ohishi, K., Hou, M. および8人, Depei, W., Takenaka, K., Liu, T., Hu, Y., Amagasaki, T., Ito, K., Gopalakrishna, P. & Akashi, K., 7 1 2015, : : Leukemia and Lymphoma. 56, 7, p. 2067-2074 8 p.

研究成果: Contribution to journalArticle

18 引用 (Scopus)

M2 macrophages enhance pathological neovascularization in the mouse model of oxygen-induced retinopathy

Zhou, Y., Yoshida, S., Nakao, S., Yoshimura, T., Kobayashi, Y., Nakama, T., Kubo, Y., Miyawaki, K., Yamaguchi, M., Ishikawa, K., Oshima, Y., Akashi, K. & Ishibashi, T., 1 1 2015, : : Investigative Ophthalmology and Visual Science. 56, 8, p. 4767-4777 11 p.

研究成果: Contribution to journalArticle

29 引用 (Scopus)