研究成果 1985 2019

フィルター
記事
2019

A Convenient Preparation Method for Benzophenone Imine Catalyzed by Tetrabutylammonium Fluoride

Kondo, Y., Morisaki, K., Hirazawa, Y., Morimoto, H. & Ohshima, T., 8 16 2019, : : Organic Process Research and Development. 23, 8, p. 1718-1724 7 p.

研究成果: ジャーナルへの寄稿記事

Imines
imines
fluorides
preparation
synthesis
1 引用 (Scopus)

Ammonium Salt-Accelerated Hydrazinolysis of Unactivated Amides: Mechanistic Investigation and Application to a Microwave Flow Process

Noshita, M., Shimizu, Y., Morimoto, H., Akai, S., Hamashima, Y., Ohneda, N., Odajima, H. & Ohshima, T., 4 19 2019, : : Organic Process Research and Development. 23, 4, p. 588-594 7 p.

研究成果: ジャーナルへの寄稿記事

hydrazine
Ammonium Compounds
Amides
amides
Salts
2 引用 (Scopus)

Development of Turn-On Probes for Acids Triggered by Aromaticity Enhancement Using Tricyclic Amidine Derivatives

Matsumoto, S., Fuchi, Y., Usui, K., Hirai, G. & Karasawa, S., 6 7 2019, : : Journal of Organic Chemistry. 84, 11, p. 6612-6622 11 p.

研究成果: ジャーナルへの寄稿記事

Amidines
Fluorescence
Protonation
Quantum yield
Derivatives
公開
DNA-Directed DNA Polymerase
DNA Polymerase I
Adenosine
Nucleotides
Derivatives

Enhancement of saccharothriolide production and discovery of a new metabolite, saccharothriolide C 2 , by combined-culture of Saccharothrix sp. and Tsukamurella pulmonis

Jiang, Y., Lu, S., Hirai, G., Kato, T., Onaka, H. & Kakeya, H., 4 11 2019, : : Tetrahedron Letters. 60, 15, p. 1072-1074 3 p.

研究成果: ジャーナルへの寄稿記事

Mycolic Acids
Metabolites
Bacteria

Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10

Yokoyama, T., Yukuhiro, M., Iwasaki, Y., Tanaka, C., Sankoda, K., Fujiwara, R., Shibuta, A., Higashi, T., Motoyama, K., Arima, H., Yoshida, K., Sugimoto, N., Morimoto, H., Kosako, H., Ohshima, T. & Fujita, M., 12 1 2019, : : Scientific reports. 9, 1, 16825.

研究成果: ジャーナルへの寄稿記事

公開
Antimitotic Agents
Antineoplastic Agents
polyoxyethylene(10)nonylphenyl ether
Karyopherins
HCT116 Cells

Mechanistic insight into catalytic aerobic chemoselective α-oxidation of acylpyrazoles

Taninokuchi, S., Yazaki, R. & Ohshima, T., 1 1 2019, : : Heterocycles. 99, 2, p. 906-918 13 p.

研究成果: ジャーナルへの寄稿記事

公開
Catalysis
Lewis Acids
Oxidation
Hydroxy Acids
Isotopes

Nuciferols A and B: Novel sesquineolignans from Cocos nucifera

Elsbaey, M., Jie, B., Tanaka, C., Kato, H., Tsukamoto, S., Usui, K., Hirai, G. & Miyamoto, T., 8 15 2019, : : Tetrahedron Letters. 60, 33, 150948.

研究成果: ジャーナルへの寄稿記事

Cocos
Scavenging
Neuroprotective Agents
Cell death
Skeleton

Study of the inducible cross-linking reaction to mRNA and the effect on the translation

Kikuta, K., Taniguchi, Y. & Sasaki, S., 1 1 2019, : : Chemical and Pharmaceutical Bulletin. 67, 8, p. 877-883 7 p.

研究成果: ジャーナルへの寄稿記事

公開
Cross Reactions
Derivatives
Messenger RNA
Oligoribonucleotides
Uracil
Oligonucleotides
Pseudouridine
Derivatives
Uracil
Oligodeoxyribonucleotides

Synthesis of All Stereoisomers of Monomeric Spectomycin A1/A2 and Evaluation of Their Protein SUMOylation-Inhibitory Activity

Nomura, Y., Thuaud, F., Sekine, D., Ito, A., Maeda, S., Koshino, H., Hashizume, D., Muranaka, A., Cruchter, T., Uchiyama, M., Ichikawa, S., Matsuda, A., Yoshida, M., Hirai, G. & Sodeoka, M., 6 21 2019, : : Chemistry - A European Journal. 25, 35, p. 8387-8392 6 p.

研究成果: ジャーナルへの寄稿記事

Stereoisomerism
Isomers
Stereochemistry
Proteins
Optical rotation
1 引用 (Scopus)

Synthesis of All Stereoisomers of RK460 and Evaluation of Their Activity and Selectivity as Abscisic Acid Receptor Antagonists

Mikame, Y., Yoshida, K., Hashizume, D., Hirai, G., Nagasawa, K., Osada, H. & Sodeoka, M., 3 7 2019, : : Chemistry - A European Journal. 25, 14, p. 3496-3500 5 p.

研究成果: ジャーナルへの寄稿記事

Abscisic Acid
Stereochemistry
Stereoisomerism
Agrochemicals
Lead compounds
3 引用 (Scopus)

Synthesis of CH 2 -Linked α(1,6)-Disaccharide Analogues by α-Selective Radical Coupling C-Glycosylation

Kiya, N., Hidaka, Y., Usui, K. & Hirai, G., 3 15 2019, : : Organic Letters. 21, 6, p. 1588-1592 5 p.

研究成果: ジャーナルへの寄稿記事

Glycosylation
Glycoconjugates
Disaccharides
carbohydrates
linkages

Synthesis of the deuterated thymidine-d9 and deuterated oligonucleotides

Taniguchi, Y., Cao, X. & Sasaki, S., 9 19 2019, : : Tetrahedron Letters. 60, 38, 151037.

研究成果: ジャーナルへの寄稿記事

Oligonucleotides
Thymidine
Glycosylation
Sugars
DNA

Synthesis of γ-N-modified 8-oxo-2’-deoxyguanosine triphosphate and its characterization

Thavoncharoensub, N., Maruyama, K., Heh, C. H., Hoong Leong, K., Shi, H., Shigematsu, Y., Sasaki, S. & Taniguchi, Y., 8 3 2019, : : Nucleosides, Nucleotides and Nucleic Acids. 38, 8, p. 578-589 12 p.

研究成果: ジャーナルへの寄稿記事

DNA-Directed DNA Polymerase
Nucleotides
DNA Replication
Reactive Oxygen Species
Repair

Thionoesters as 1,2-Dipolarophiles for [4+2] Cycloaddition with Cyclobutanones

Matsumoto, Y., Tsuji, T., Nakatake, D., Yazaki, R. & Ohshima, T., 7 1 2019, : : Asian Journal of Organic Chemistry. 8, 7, p. 1071-1074 4 p.

研究成果: ジャーナルへの寄稿記事

Cycloaddition
Carbon Monoxide
Biological Products
Ketones
Carbon
2018
5 引用 (Scopus)

3-Mono-Substituted BINOL Phosphoric Acids as Effective Organocatalysts in Direct Enantioselective Friedel–Crafts-Type Alkylation of N-Unprotected α-Ketiminoester

Yonesaki, R., Kondo, Y., Akkad, W., Sawa, M., Morisaki, K., Morimoto, H. & Ohshima, T., 10 12 2018, : : Chemistry - A European Journal. 24, 57, p. 15211-15214 4 p.

研究成果: ジャーナルへの寄稿記事

Phosphoric Acids
Enantioselectivity
Alkylation
Phosphoric acid
Catalysts
24 引用 (Scopus)
Cyclopropanes
Cycloaddition
Catalysis
Iron
tetrahydrothiophene
1 引用 (Scopus)

Bioconjugation with Thiols by Benzylic Substitution

Watanabe, K. & Ohshima, T., 3 15 2018, : : Chemistry - A European Journal. 24, 16, p. 3959-3964 6 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Sulfhydryl Compounds
Substitution reactions
Enzymes
Kinetics
9 引用 (Scopus)

Catalytic Enantioselective Decarboxylative Mannich-Type Reaction of N-Unprotected Isatin-Derived Ketimines

Sawa, M., Miyazaki, S., Yonesaki, R., Morimoto, H. & Ohshima, T., 9 7 2018, : : Organic Letters. 20, 17, p. 5393-5397 5 p.

研究成果: ジャーナルへの寄稿記事

Isatin
synthesis
AG-041R
ketimine
Oligonucleotides
Nucleic Acids
Genes
DNA sequences
Nucleosides
10 引用 (Scopus)

Chemoselective Catalytic Dehydrogenative Cross-Coupling of 2-Acylimidazoles: Mechanistic Investigations and Synthetic Scope

Tanaka, T., Hashiguchi, K., Tanaka, T., Yazaki, R. & Ohshima, T., 9 7 2018, : : ACS Catalysis. 8, 9, p. 8430-8440 11 p.

研究成果: ジャーナルへの寄稿記事

phosphine
Carbon
Iron
Chemical activation
Alkanes
1 引用 (Scopus)
Carbonyl compounds
Rhodium
Catalysts
Proton transfer
Thalidomide
2 引用 (Scopus)

Evaluation of simultaneous binding of Chromomycin A3 to the multiple sites of DNA by the new restriction enzyme assay

Murase, H., Noguchi, T. & Sasaki, S., 6 1 2018, : : Bioorganic and Medicinal Chemistry Letters. 28, 10, p. 1832-1835 4 p.

研究成果: ジャーナルへの寄稿記事

Chromomycin A3
DNA Restriction Enzymes
Enzyme Assays
Assays
DNA

Fluorescence tumor-imaging using a thermo-responsive molecule with an emissive aminoquinoline derivative

Araki, T., Fuchi, Y., Murayama, S., Shiraishi, R., Oyama, T., Aso, M., Aoki, I., Kobayashi, S., Yamada, K. I. & Karasawa, S., 10 2 2018, : : Nanomaterials. 8, 10, 782.

研究成果: ジャーナルへの寄稿記事

Aminoquinolines
Tumors
Fluorescence
Derivatives
Imaging techniques

Growth suppression of human colorectal cancer cells with mutated KRAS by 3-deaza-cytarabine in 3d floating culture

Luo, H., Nishi, K., Ishikura, S., Swain, A., Morishige, N., Yazaki, R., Ohshima, T., Shirasawa, S. & Tsunoda, T., 7 1 2018, : : Anticancer research. 38, 7, p. 4247-4256 10 p.

研究成果: ジャーナルへの寄稿記事

Cytarabine
Colorectal Neoplasms
Uridine
Growth
gemcitabine
3 引用 (Scopus)

Internal-Edge-Substituted Coumarin-Fused [6]Helicenes: Asymmetric Synthesis, Structural Features, and Control of Self-Assembly

Usui, K., Yamamoto, K., Ueno, Y., Igawa, K., Hagihara, R., Masuda, T., Ojida, A., Karasawa, S., Tomooka, K., Hirai, G. & Suemune, H., 10 1 2018, : : Chemistry - A European Journal. 24, 55, p. 14617-14621 5 p.

研究成果: ジャーナルへの寄稿記事

Self assembly
X ray crystallography
Quantum yield
Electronic structure
Physical properties
5 引用 (Scopus)

Luminescent europium sensors for specific detection of 8-oxo-dGTP by time-gated fluorescence

Fuchi, Y., Fukuda, T. & Sasaki, S., 7 23 2018, : : Bioorganic and Medicinal Chemistry. 26, 12, p. 3254-3260 7 p.

研究成果: ジャーナルへの寄稿記事

Europium
Fluorescence
Sensors
Assays
Ions
2 引用 (Scopus)
Aminopyridines
Base Pairing
DNA
Nucleosides
Nucleotides
3 引用 (Scopus)
Leukemia
Derivatives
Cephalotaxus
Immunosorbents
Acute Promyelocytic Leukemia

Stable and selective antiparallel type triplex DNA formation by targeting a GC base pair with the TFO containing one N2-phenyl-2-deoxyguanosine

Taniguchi, Y., Miyazaki, M., Matsueda, N., Wang, L., Okamura, H. & Sasaki, S., 1 1 2018, : : Chemical and Pharmaceutical Bulletin. 66, 6, p. 624-631 8 p.

研究成果: ジャーナルへの寄稿記事

Deoxyguanosine
Oligonucleotides
Base Pairing
DNA
Gene expression
8 引用 (Scopus)

Strategy for Catalytic Chemoselective Cross-Enolate Coupling Reaction via a Transient Homocoupling Dimer

Tanaka, T., Tanaka, T., Tsuji, T., Yazaki, R. & Ohshima, T., 6 15 2018, : : Organic Letters. 20, 12, p. 3541-3544 4 p.

研究成果: ジャーナルへの寄稿記事

cross coupling
Catalysis
Dimers
catalysis
Bearings (structural)

Synthesis of dendritic bisphosphonates as bone targeting ligands

Shimoda, K., Mitsuoka, T., Ueda, K., Suemune, H., Hirai, G. & Aso, M., 12 19 2018, : : Tetrahedron Letters. 59, 51, p. 4528-4531 4 p.

研究成果: ジャーナルへの寄稿記事

Diphosphonates
Bone
Ligands
Bone and Bones
Durapatite
6 引用 (Scopus)

Thienyl-Substituted α-Ketoamide: A Less Hydrophobic Reactive Group for Photo-Affinity Labeling

Ota, E., Usui, K., Oonuma, K., Koshino, H., Nishiyama, S., Hirai, G. & Sodeoka, M., 4 20 2018, : : ACS Chemical Biology. 13, 4, p. 876-880 5 p.

研究成果: ジャーナルへの寄稿記事

Mannose
Labeling
Photolysis
Concanavalin A
Hydrophobic and Hydrophilic Interactions
2017
1 引用 (Scopus)

7-Hydroxy-3-methyleneisoindolin-1-one as a New ESIPT-Fluorescent Probe to Monitor Aqueous Environments

Kimuro, Y., Usui, K., Karasawa, S., Hirai, G. & Aso, M., 2017, : : Chemical and Pharmaceutical Bulletin. 65, 8, p. 796-800 5 p.

研究成果: ジャーナルへの寄稿記事

Proton transfer
Fluorescent Dyes
Excited states
Protons
Density functional theory
10 引用 (Scopus)

Boronic Acid Accelerated Three-Component Reaction for the Synthesis of α-Sulfanyl-Substituted Indole-3-acetic Acids

Das, A., Watanabe, K., Morimoto, H. & Ohshima, T., 11 3 2017, : : Organic Letters. 19, 21, p. 5794-5797 4 p.

研究成果: ジャーナルへの寄稿記事

Boronic Acids
indoles
acetic acid
Indoles
acids
12 引用 (Scopus)

Catalytic Aerobic Chemoselective α-Oxidation of Acylpyrazoles en Route to α-Hydroxy Acid Derivatives

Taninokuchi, S., Yazaki, R. & Ohshima, T., 6 16 2017, : : Organic Letters. 19, 12, p. 3187-3190 4 p.

研究成果: ジャーナルへの寄稿記事

Lewis Acids
Hydroxy Acids
Carboxylic Acids
Biological Products
Catalysis
4 引用 (Scopus)
Amino Alcohols
Transesterification
Esters
Catalysis
Lewis Acids
1 引用 (Scopus)

Development of damaged nucleoside mimics for inhibition of their repair enzymes

Taniguchi, Y., 1 1 2017, : : Yakugaku Zasshi. 137, 3, p. 293-300 8 p.

研究成果: ジャーナルへの寄稿記事

Nucleosides
Enzymes
Hydrolysis
Nucleotides
Neoplasms
12 引用 (Scopus)
Proton transfer
Carboxylic Acids
Carboxylic acids
Amines
propargylamine
13 引用 (Scopus)
Amino acids
Esters
Amino Acids
Nucleophiles
Addition reactions
41 引用 (Scopus)

Direct Catalytic Alcoholysis of Unactivated 8-Aminoquinoline Amides

Deguchi, T., Xin, H. L., Morimoto, H. & Ohshima, T., 5 5 2017, : : ACS Catalysis. 7, 5, p. 3157-3161 5 p.

研究成果: ジャーナルへの寄稿記事

Amides
Functional groups
Esters
Alcohols
Catalysts
3 引用 (Scopus)

Direct enantioselective alkynylation of α-ketoesters and α-ketiminoesters catalyzed by [bis(oxazoline)phenyl]rhodium(III) complexes

Morisaki, K., Morimoto, H., Mashima, K. & Ohshima, T., 1 1 2017, : : Heterocycles. 95, 2, p. 637-661 25 p.

研究成果: ジャーナルへの寄稿記事

Rhodium
Aldehydes
Protons
Catalysts
Proton transfer
3 引用 (Scopus)
Epidemiologic Effect Modifiers
Substitution reactions
Derivatives
Hydrogen bonds
Protonation
2 引用 (Scopus)

Metabolomic profiling of brain tissues of mice chronically exposed to heroin

Li, R. S., Takeda, T., Ohshima, T., Yamada, H. & Ishii, Y., 2 2017, : : Drug Metabolism and Pharmacokinetics. 32, 1, p. 108-111 4 p.

研究成果: ジャーナルへの寄稿記事

Metabolomics
Heroin
Brain
Melatonin
Catecholamines
7 引用 (Scopus)

Self-Assembly Behavior of Emissive Urea Benzene Derivatives Enables Heat-Induced Accumulation in Tumor Tissue

Araki, T., Murayama, S., Usui, K., Shimada, T., Aoki, I. & Karasawa, S., 4 12 2017, : : Nano Letters. 17, 4, p. 2397-2403 7 p.

研究成果: ジャーナルへの寄稿記事

Benzene Derivatives
ureas
Urea
Self assembly
self assembly
9 引用 (Scopus)

Sodium periodate-mediated conjugation of harringtonine enabling the production of a highly specific monoclonal antibody, and the development of a sensitive quantitative analysis method

Sakamoto, S., Yusakul, G., Tsuneura, Y., Putalun, W., Usui, K., Miyamoto, T., Tanaka, H. & Morimoto, S., 4 7 2017, : : Analyst. 142, 7, p. 1140-1148 9 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal antibodies
quantitative analysis
antibody
Monoclonal Antibodies
Sodium
Leukemia
Derivatives
Cephalotaxus
Immunosorbents
Acute Promyelocytic Leukemia
6 引用 (Scopus)

Synchronized Chiral Induction between [5]Helicene–Spermine Ligand and B–Z DNA Transition

Kawara, K., Tsuji, G., Taniguchi, Y. & Sasaki, S., 1 1 2017, : : Chemistry - A European Journal. 23, 8, p. 1763-1769 7 p.

研究成果: ジャーナルへの寄稿記事

Chirality
DNA
Ligands
Z-Form DNA
B-Form DNA