先端医療医学部門

研究成果

年別の研究成果 1984 2009 2010 2011 2012 2013 2014 2015 2016 2017 2022

• 715 学術誌
• 80 会議への寄与
• 53 総説
• 12 会議記事
• 39 その他
  • 12 レター
  • 7 コメント/討論
  • 6 章
  • 6 編集
  • 5 学会誌
  • 3 簡易調査

年別の研究成果

年別の研究成果

検索結果

• 2022

  Clinical Challenges in Diagnosis, Tumor Localization and Treatment of Tumor-Induced Osteomalacia: Outcome of a Retrospective Surveillance

  Hidaka, N., Koga, M., Kimura, S., Hoshino, Y., Kato, H., Kinoshita, Y., Makita, N., Nangaku, M., Horiguchi, K., Furukawa, Y., Ohnaka, K., Inagaki, K., Nakagawa, A., Suzuki, A., Takeuchi, Y., Fukumoto, S., Nakatani, F. & Ito, N., 2022, (印刷中) In: Journal of Bone and Mineral Research.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Patient 100%
  • Osteomalacia 63%
  • Neoplasm 54%
  • Bone 27%
  • Positron Emission Tomography-Computed Tomography 27%
  4 被引用数 (Scopus)

• Contribution of pre-existing neoantigen-specific T cells to a durable complete response after tumor-pulsed dendritic cell vaccine plus nivolumab therapy in a patient with metastatic salivary duct carcinoma

  Ichimiya, S., Fujimura, A., Masuda, M., Masuda, S., Yasumatsu, R., Umebayashi, M., Tanaka, H., Koya, N., Nakagawa, S., Yew, P. Y., Yoshimura, S., Onishi, H., Nakamura, M., Nakamura, Y. & Morisaki, T., 2022, In: Immunological Investigations. 51, 5, p. 1498-1514 17 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Neoantigen 100%
  • Dendritic Cell Vaccine 57%
  • Cells 28%
  • Immunity 28%
  • Cell Lysate 28%
  2 被引用数 (Scopus)

• ERAP2 is a novel target involved in autophagy and activation of pancreatic stellate cells via UPR signaling pathway

  Guan, W., Nakata, K., Sagara, A., Iwamoto, C., Endo, S., Matsuda, R., Matsumoto, S., Ikenaga, N., Shindo, K., Moriyama, T., Onishi, H., Ohuchida, K., Oda, Y. & Nakamura, M., 1月 2022, In: Pancreatology. 22, 1, p. 9-19 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Pancreatic Stellate Cell 100%
  • Autophagy 80%
  • Endoplasmic reticulum 60%
  • Aminopeptidase 60%
  • Pancreas Adenocarcinoma 50%
  2 被引用数 (Scopus)

• Impact of Antithrombin Activity Levels Following Recombinant Antithrombin Gamma Therapy in Patients with Sepsis-Induced Disseminated Intravascular Coagulation

  Akahoshi, T., Kaku, N., Shono, Y., Yamamoto, Y., Takahashi, K., Iyonaga, T., Momii, K., Nishihara, M., Maki, J., Tokuda, K. & Yamaura, K., 2022, In: Clinical and Applied Thrombosis/Hemostasis. 28

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Disseminated Intravascular Clotting 100%
  • Patient 50%
  • Recombinant Antithrombin III 50%
  • Dose 33%
  • Inpatient 33%
  1 被引用数 (Scopus)

• Maxillofacial injury caused by bamboo skewer penetrating the cranial cavity

  Kondo, T., Kaku, N., Hanaki, Y., Tsuchihashi, N. & Akahoshi, T., 1月 1 2022, In: Pediatrics International. 64, 1, p. e15018

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

• Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model

  Yamaguchi, K., Yoshihiro, T., Ariyama, H., Ito, M., Nakano, M., Semba, Y., Nogami, J., Tsuchihashi, K., Yamauchi, T., Ueno, S., Isobe, T., Shindo, K., Moriyama, T., Ohuchida, K., Nakamura, M., Nagao, Y., Ikeda, T., Hashizume, M., Konomi, H., Torisu, T., & 8 othersKitazono, T., Kanayama, T., Tomita, H., Oda, Y., Kusaba, H., Maeda, T., Akashi, K. & Baba, E., 6月 4 2022, (印刷前の電子出版) In: Gastric Cancer.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Signet Ring Cell Carcinoma 100%
  • Uvomorulin 77%
  • Organoid 55%
  • Cells 44%
  • Combination Therapy 33%
  2 被引用数 (Scopus)

• Prediction of intracranial lesions in patients with consciousness disturbance by ultrasonography in the intensive care unit

  Shono, Y., Mezuki, S., Akahoshi, T., Nishihara, M., Kaku, N., Maki, J., Tokuda, K. & Kitazono, T., 9月 2022, In: Journal of International Medical Research. 50, 9

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Patient 100%
  • Lesion 100%
  • Echography 80%
  • Intensive Care Unit 80%
  • Inpatient 60%

• PTPN3 Could Be a Therapeutic Target of Pancreatic Cancer

  Ohnishi, H., Iwamoto, N., Sakanashi, K., Koga, S., Oyama, Y., Yanai, K., Nakamura, K., Nagai, S., Fujimura, A., Nakayama, K., Ozono, K. & Yamasaki, A., 6月 2022, In: Anticancer research. 42, 6, p. 2869-2874 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Non Receptor Protein Tyrosine Phosphatase 3 100%
  • Protein Tyrosine Phosphatase 100%
  • Pancreas Cancer 50%
  • Combination Therapy 37%
  • Western Blot 37%

• Radiation Emergency Medical Preparedness in Japan: A Survey of Nuclear Emergency Core Hospitals

  Nagata, T., Arishima, T., Yamaguchi, Y., Hirohashi, N., Usa, T., Hasegawa, A., Hanada, H., Yamamoto, N., Okamoto, T., Akahoshi, T., Hamada, M., Abe, T., Kikukawa, M., Nakao, H., Yamamura, H., Sakamoto, T., Akashi, M. & Hagihara, A., 2022, (印刷中) In: Disaster Medicine and Public Health Preparedness.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Radiation 100%
  • Hospitals 75%
  • Disasters 75%
  • Emergency 75%
  • Hospital 75%
  1 被引用数 (Scopus)

• Tropomyosin-related Kinase B Is Potentially a Biomarker of Prognosis and Therapeutic Target for Malignant Thymic Epithelial Tumors

  Ozono, K., Onishi, H., Iwamoto, N., Nakamura, K., Miyoshi, K., Nakamura, M. & Oda, Y., 8月 2022, In: Anticancer research. 42, 8, p. 3779-3787 9 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Phosphotransferase 100%
  • Epithelium Tumor 100%
  • Receptor 87%
  • Brain Derived Neurotrophic Factor 50%
  • Prognosis 37%
• 2021

  Development of 20 cm sample bore size dynamic nuclear polarization (DNP)-MRI at 16 mT and redox metabolic imaging of acute hepatitis rat model

  Eto, H., Naganuma, T., Nakao, M., Murata, M., Elhelaly, A. E., Noda, Y., Kato, H., Matsuo, M., Akahoshi, T., Hashizume, M. & Hyodo, F., 6月 2021, In: Free Radical Biology and Medicine. 169, p. 149-157 9 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Magnetic Resonance Imaging 100%
  • Dynamic Nuclear Polarization 100%
  • Redox Metabolism 44%
  • Dynamics 33%
  • Sample 22%

• Efficacy of thromboelastography in the management of anticoagulation for veno-venous extracorporeal membrane oxygenation in a coronavirus disease 2019 patient

  Nakashima, R., Nishihara, M., Iyonaga, T., Iwasaka, S., Yamamoto, Y., Shono, Y., Maki, J., Tokuda, K., Akahoshi, T., Higo, T., Kitazono, T. & Tsutsui, H., 4月 2 2021, In: Medicine (United States). 100, 23, e26313.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Extracorporeal Membrane Oxygenation 100%
  • Heparin 85%
  • Patient 71%
  • COVID-19 71%
  • Marker 42%
  2 被引用数 (Scopus)

• Establishment and characterization of a primary cell culture derived from external auditory canal squamous cell carcinoma

  Sekino, Y., Imaizumi, A., Komune, N., Ono, M., Sato, K., Masuda, S., Fujimura, A., Koike, K., Hongo, T., Uchi, R., Onishi, H. & Nakagawa, T., 8月 2021, In: FEBS Open Bio. 11, 8, p. 2211-2224 14 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Cells 100%
  • Squamous Cell Carcinoma 100%
  • Cell Culture 100%
  • External Auditory Canal 100%
  • Feeder Cell 100%
  3 被引用数 (Scopus)

• GLI2 but not GLI1/GLI3 plays a central role in the induction of malignant phenotype of gallbladder cancer

  Ichimiya, S., Onishi, H., Nagao, S., Koga, S., Sakihama, K., Nakayama, K., Fujimura, A., Oyama, Y., Imaizumi, A., Oda, Y. & Nakamura, M., 3月 2021, In: Oncology reports. 45, 3, p. 997-1010 14 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • GLI2 100%
  • Gallbladder 100%
  • Gallbladder Cancer 100%
  • GLI1 66%
  • GLI3 66%
  1 被引用数 (Scopus)

• Histidine-Rich Glycoprotein Alleviates Liver Ischemia/Reperfusion Injury in Mice With Nonalcoholic Steatohepatitis

  Guo, J., Akahoshi, T., Mizuta, Y., Murata, M., Narahara, S., Kawano, T., Nagao, Y., Zhang, S., Tomikawa, M., Kawanaka, H. & Hashizume, M., 6月 2021, In: Liver Transplantation. 27, 6, p. 840-853 14 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Glycoprotein 100%
  • Histidine 100%
  • Reperfusion Injury 53%
  • Nonalcoholic Fatty Liver 46%
  • Diet 38%
  6 被引用数 (Scopus)

• PTPN3 is a potential target for a new cancer immunotherapy that has a dual effect of T cell activation and direct cancer inhibition in lung neuroendocrine tumor

  Koga, S., Onishi, H., Masuda, S., Fujimura, A., Ichimiya, S., Nakayama, K., Imaizumi, A., Nishiyama, K., Kojima, M., Miyoshi, K., Nakamura, K., Umebayashi, M., Morisaki, T. & Nakamura, M., 9月 2021, In: Translational Oncology. 14, 9, 101152.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Protein Tyrosine Phosphatase 100%
  • Lung 50%
  • Lymphocyte 31%
  • Cancer Cell 25%
  • Small Cell Lung Cancer 25%
  8 被引用数 (Scopus)

• Reflectance spectra analysis for mucous assessment

  Chiba, T., Murata, M., Kawano, T., Hashizume, M. & Akahoshi, T., 2021, In: World Journal of Gastrointestinal Oncology. 13, 8, p. 822-834 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Diagnosis 100%
  • Tissues 66%
  • Analysis 66%
  • Development 33%
  • Malignant Neoplasm 33%

• The effect of real-time monitoring of physical activity intensity in diabetic patients

  Tanaka, R., Fujita, K., Maeno, S., Yakushiji, K., Tanaka, S., Ohnaka, K., Ashida, K., Sakamoto, S. & Nomura, M., 2021, (印刷中) In: Japan Journal of Nursing Science.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Control 100%
  • Hemoglobin A1c 75%
  • Diabetes Mellitus 75%
  • Patient 75%
  • Time 50%

• Trkb/bdnf signaling could be a new therapeutic target for pancreatic cancer

  OYAMA, YASUHIRO., NAGAO, SHINJIRO., NA, LIN., YANAI, KOSUKE., UMEBAYASHI, MASAYO., NAKAMURA, KATSUYA., Nagai, S., FUJIMURA, AKIKO., YAMASAKI, AKIO., NAKAYAMA, KAZUNORI., MORISAKI, TAKASHI. & ONISHI, HIDEYA., 8月 2021, In: Anticancer research. 41, 8, p. 4047-4052 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Phosphotransferase 100%
  • Tropomyosin 100%
  • Kinase 100%
  • Brain Derived Neurotrophic Factor 80%
  • Brain-Derived Neurotrophic Factor 80%
  6 被引用数 (Scopus)
• 2020

  Alteration in faecal bile acids, gut microbial composition and diversity after laparoscopic sleeve gastrectomy

  Ikeda, T., Aida, M., Yoshida, Y., Matsumoto, S., Tanaka, M., Nakayama, J., Nagao, Y., Nakata, R., Oki, E., Akahoshi, T., Okano, S., Nomura, M., Hashizume, M. & Maehara, Y., 11月 1 2020, In: British Journal of Surgery. 107, 12, p. 1673-1685 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Laparoscopic Sleeve Gastrectomy 100%
  • Bile Acid 71%
  • Bile 71%
  • Feces 57%
  • Cells 42%
  15 被引用数 (Scopus)

• Clinical improvement in a patient with severe coronavirus disease 2019 after administration of hydroxychloroquine and continuous hemodiafiltlation with nafamostat mesylate

  Iwasaka, S., Shono, Y., Tokuda, K., Nakashima, K., Yamamoto, Y., Maki, J., Nagasaki, Y., Shimono, N., Akahoshi, T. & Taguchi, T., 12月 2020, In: Journal of Infection and Chemotherapy. 26, 12, p. 1319-1323 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • COVID-19 100%
  • Clinical Study 33%
  • Nafamstat Mesilate 33%
  • Patient 25%
  • Therapeutic Procedure 25%
  7 被引用数 (Scopus)

• Development of a novel molecular probe for the detection of liver mitochondrial redox metabolism

  Hosain, M. Z., Hyodo, F., Mori, T., Takahashi, K., Nagao, Y., Eto, H., Murata, M., Akahoshi, T., Matsuo, M. & Katayama, Y., 12月 1 2020, In: Scientific reports. 10, 1, 16489.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Probe 100%
  • Molecular Probe 25%
  • Mitochondrion 25%
  • Oxidative Stress 16%
  • Development 16%

• Exosomes from adipose tissue-derived mesenchymal stem cells ameliorate histone-induced acute lung injury by activating the PI3K/Akt pathway in endothelial cells

  Mizuta, Y., Akahoshi, T., Guo, J., Zhang, S., Narahara, S., Kawano, T., Murata, M., Tokuda, K., Eto, M., Hashizume, M. & Yamaura, K., 12月 2020, In: Stem Cell Research and Therapy. 11, 1, 508.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Stem Cell 100%
  • Adipose-Derived Mesenchymal Stem Cell 85%
  • Histone 71%
  • Exosome 28%
  • Phosphorylation 21%
  27 被引用数 (Scopus)

• FAM115C could be a novel tumor suppressor associated with prolonged survival in pancreatic cancer patients

  Saeki, K., Onishi, H., Koga, S., Ichimiya, S., Nakayama, K., Oyama, Y., Kawamoto, M., Sakihama, K., Yamamoto, T., Matsuda, R., Miyasaka, Y., Nakamura, M. & Oda, Y., 2020, In: Journal of Cancer. 11, 8, p. 2289-2302 14 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Pancreas Adenocarcinoma 100%
  • Tumor Suppressor Protein 44%
  • Hypoxia 33%
  • Cells 22%
  • Gene 22%
  5 被引用数 (Scopus)

• Intranodal Administration of Neoantigen Peptide-loaded Dendritic Cell Vaccine Elicits Epitope-specific T Cell Responses and Clinical Effects in a Patient with Chemorefractory Ovarian Cancer with Malignant Ascites

  Morisaki, T., Hikichi, T., Onishi, H., Morisaki, T., Kubo, M., Hirano, T., Yoshimura, S., Kiyotani, K. & Nakamura, Y., 2020, In: Immunological Investigations. p. 1-18 18 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Neoantigen 100%
  • Immunotherapy 25%
  • Lymphocyte 25%
  • T Cell Receptor 12%
  • Mutant 12%
  18 被引用数 (Scopus)

• NFκB and TGFβ contribute to the expression of PTPN3 in activated human lymphocytes

  Nakayama, K., Onishi, H., Fujimura, A., Imaizumi, A., Kawamoto, M., Oyama, Y., Ichimiya, S., Koga, S., Fujimoto, Y., Nakashima, K. & Nakamura, M., 12月 2020, In: Cellular Immunology. 358, 104237.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Lymphocyte 100%
  • Non Receptor Protein Tyrosine Phosphatase 3 57%
  • Immunity 14%
  • Immunotherapy 14%
  • Biological Activity 7%
  2 被引用数 (Scopus)

• Patched 1-interacting peptide represses fibrosis in pancreatic cancer to augment the effectiveness of immunotherapy

  Oyama, Y., Onishi, H., Koga, S., Murahashi, M., Ichimiya, S., Nakayama, K., Fujimura, A., Kawamoto, M., Imaizumi, A., Umebayashi, M., Ohuchida, K., Morisaki, T. & Nakamura, M., 5月 1 2020, In: Journal of Immunotherapy. 43, 4, p. 121-133 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Peptide 100%
  • Pancreas Adenocarcinoma 75%
  • Malignant Neoplasm 62%
  • Fibrosis 62%
  • Immunocompetent Cell 50%
  14 被引用数 (Scopus)

• Prognostic factors for the short-term mortality of patients with rheumatoid arthritis admitted to intensive care units

  Fujiwara, T., Tokuda, K., Momii, K., Shiomoto, K., Tsushima, H., Akasaki, Y., Ikemura, S., Fukushi, J. I., Maki, J., Kaku, N., Akahoshi, T., Taguchi, T. & Nakashima, Y., 12月 2020, In: BMC Rheumatology. 4, 1, 64.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Patient 100%
  • Intensive Care Unit 83%
  • Rheumatoid Arthritis 50%
  • Inflammatory Arthritis 50%
  • Mortality 41%
  3 被引用数 (Scopus)

• Self-Propelled Colonoscopy Robot Using Flexible Paddles

  Osawa, K., Nakadate, R., Arata, J., Nagao, Y., Akahoshi, T., Eto, M. & Hashizume, M., 10月 2020, In: IEEE Robotics and Automation Letters. 5, 4, p. 6710-6716 7 p., 9170783.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Robotics 100%
  • Robot 83%
  • Force 50%
  • Self Concept 50%
  • Colon 50%
  7 被引用数 (Scopus)

• Sodium thiosulfate prevents doxorubicin-induced DNA damage and apoptosis in cardiomyocytes in mice

  Mizuta, Y., Tokuda, K., Guo, J., Zhang, S., Narahara, S., Kawano, T., Murata, M., Yamaura, K., Hoka, S., Hashizume, M. & Akahoshi, T., 7月 13 2020, (印刷前の電子出版) In: Life Sciences. 257, p. 118074

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Doxorubicin 100%
  • Sodium Thiosulfate 61%
  • Apoptosis 19%
  • DNA 14%
  • Antioxidant 14%
  16 被引用数 (Scopus)

• Surgical Navigation Improves Renal Parenchyma Volume Preservation in Robot-Assisted Partial Nephrectomy: A Propensity Score Matched Comparative Analysis

  Kobayashi, S., Cho, B., Mutaguchi, J., Inokuchi, J., Tatsugami, K., Hashizume, M. & Eto, M., 7月 1 2020, In: The Journal of urology. 204, 1, p. 149-156 8 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Parenchyma 100%
  • Partial Nephrectomy 80%
  • Patient 40%
  • Analysis 40%
  • Neoplasm 20%
  6 被引用数 (Scopus)

• The farnesyltransferase inhibitor tipifarnib protects against autoimmune hepatitis induced by Concanavalin A

  Guo, J., Shirozu, K., Akahoshi, T., Mizuta, Y., Murata, M. & Yamaura, K., 6月 2020, In: International Immunopharmacology. 83, 106462.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Concanavalin A 100%
  • Tipifarnib 100%
  • Autoimmune Hepatitis 36%
  • T Cell 36%
  • CD4 36%
  1 被引用数 (Scopus)
• 2019

  A case of acute exacerbation of chronic adrenal insufficiency due to ipilimumab treatment for advanced melanoma

  Sakaguchi, C., Yano, S., Ashida, K., Wada, N., Ohe, K., Nagata, H., Matsuda, Y., Sakamoto, S., Sakamoto, R., Ohnaka, K., Uchi, H., Furue, M., Nomura, M. & Ogawa, Y., 2019, In: American Journal of Case Reports. 20, p. 106-110 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Therapeutic Procedure 100%
  • Ipilimumab 88%
  • Adrenal Insufficiency 55%
  • Case Report 44%
  • Nivolumab 44%
  6 被引用数 (Scopus)

• Colorectal endoscopic submucosal dissection using novel articulating devices: a comparative study in a live porcine model

  Okamoto, Y., Nakadate, R., Nakamura, S., Arata, J., Oguri, S., Moriyama, T., Esaki, M., Iwasa, T., Ohuchida, K., Akahoshi, T., Ikeda, T., Kitazono, T. & Hashizume, M., 2月 15 2019, In: Surgical endoscopy. 33, 2, p. 651-657 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Endoscopic Submucosal Dissection 100%
  • Perforation 60%
  • Adverse Event 40%
  • Specimen 20%
  • Colon 20%
  6 被引用数 (Scopus)

• Endoscopic surgery in Japan: The 13th national survey (2014-2015) by the Japan Society for Endoscopic Surgery

  Shiroshita, H., Inomata, M., Bandoh, T., Uchida, H., Akira, S., Hashizume, M., Yamaguchi, S., Eguchi, S., Wada, N., Takiguchi, S., Ieiri, S., Endo, S., Iwazaki, M., Tamaki, Y., Tabata, M., Kanayama, H., Mimata, H., Hasegawa, T., Onishi, K., Yanaga, K., & 6 othersMorikawa, T., Terachi, T., Matsumoto, S., Yamashita, Y., Kitano, S. & Watanabe, M., 1月 1 2019, In: Asian journal of endoscopic surgery. 12, 1, p. 7-18 12 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Endoscopic Surgery 100%
  • Development 18%
  • Patient 9%
  • Cardiovascular System 9%
  • Surgery 9%
  24 被引用数 (Scopus)

• Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout

  Kawamura, Y., Nakaoka, H., Nakayama, A., Okada, Y., Yamamoto, K., Higashino, T., Sakiyama, M., Shimizu, T., Ooyama, H., Ooyama, K., Nagase, M., Hidaka, Y., Shirahama, Y., Hosomichi, K., Nishida, Y., Shimoshikiryo, I., Hishida, A., Katsuura-Kamano, S., Shimizu, S., Kawaguchi, M., & 29 othersUemura, H., Ibusuki, R., Hara, M., Naito, M., Takao, M., Nakajima, M., Iwasawa, S., Nakashima, H., Ohnaka, K., Nakamura, T., Stiburkova, B., Merriman, T. R., Nakatochi, M., Ichihara, S., Yokota, M., Takada, T., Saitoh, T., Kamatani, Y., Takahashi, A., Arisawa, K., Takezaki, T., Tanaka, K., Wakai, K., Kubo, M., Hosoya, T., Ichida, K., Inoue, I., Shinomiya, N. & Matsuo, H., 10月 1 2019, In: Annals of the Rheumatic Diseases. 78, 10, p. 1430-1437 8 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Gout 100%
  • Hyperuricemia 52%
  • Genome Wide Association Study 47%
  • Genome-Wide Association Study 47%
  • Development 17%
  55 被引用数 (Scopus)

• Japanese periodical nationwide epidemiologic survey of aberrant portal hemodynamics

  Ohfuji, S., Furuichi, Y., Akahoshi, T., Kage, M., Obara, K., Hashizume, M., Matsuura, T., Fukushima, W. & Nakamura, Y., 8月 1 2019, In: Hepatology Research. 49, 8, p. 890-901 12 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Obstruction 100%
  • Portal Hypertension 100%
  • Syndrome 85%
  • Patient 57%
  • Cohort Effect 28%
  3 被引用数 (Scopus)

• Liprin-α4 as a new therapeutic target for SCLC as an upstream mediator of HIF1α

  Onishi, H., Yamasaki, A., Nakamura, K., Ichimiya, S., Yanai, K., Umebayashi, M., Nagai, S. & Morisaki, T., 3月 1 2019, In: Anticancer research. 39, 3, p. 1179-1184 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Small Cell Lung Cancer 100%
  • Hypoxia 100%
  • Cells 60%
  • Chemosensitivity 60%
  • Combination Therapy 40%
  8 被引用数 (Scopus)

• Pancreatic Juice Exosomal MicroRNAs as Biomarkers for Detection of Pancreatic Ductal Adenocarcinoma

  Nakamura, S., Sadakari, Y., Takao, O., Okayama, T., Nakashima, Y., Gotoh, Y., Saeki, K., Mori, Y., Nakata, K., Miyasaka, Y., Onishi, H., Oda, Y., Goggins, M. & Nakamura, M., 7月 15 2019, In: Annals of Surgical Oncology. 26, 7, p. 2104-2111 8 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Pancreas Adenocarcinoma 100%
  • Pancreatic Juice 90%
  • Patient 80%
  • Chronic Pancreatitis 60%
  • microRNA 155 60%
  48 被引用数 (Scopus)

• PTPN3 expressed in activated T lymphocytes is a candidate for a non-antibody-type immune checkpoint inhibitor

  Fujimura, A., Nakayama, K., Imaizumi, A., Kawamoto, M., Oyama, Y., Ichimiya, S., Umebayashi, M., Koya, N., Morisaki, T., Nakagawa, T. & Onishi, H., 10月 1 2019, In: Cancer Immunology, Immunotherapy. 68, 10, p. 1649-1660 12 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Lymphocyte 100%
  • Immunity 40%
  • Neoplasm 20%
  • T Cell 20%
  • Antibody 20%
  7 被引用数 (Scopus)

• The evolution of surgical treatment for gastrointestinal cancers

  Maehara, Y., Soejima, Y., Yoshizumi, T., Kawahara, N., Oki, E., Saeki, H., Akahoshi, T., Ikegami, T., Yamashita, Y. I., Furuyama, T., Sugimachi, K., Harada, N., Tagawa, T., Harimoto, N., Itoh, S., Sonoda, H., Andou, K., Nakashima, Y., Nagao, Y., Yamashita, N., & 17 othersKasagi, Y., Yukaya, T., Kurihara, T., Tsutsumi, R., Takamori, S., Sasaki, S., Ikeda, T., Yonemitsu, Y., Fukuhara, T., Kitao, H., Iimori, M., Kataoka, Y., Wakasa, T., Suzuki, M., Teraishi, K., Yoshida, Y. & Mori, M., 11月 1 2019, In: International Journal of Clinical Oncology. 24, 11, p. 1333-1349 17 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Malignant Neoplasm 100%
  • Tissues 100%
  • Gastrointestinal Cancer 75%
  • Development 50%
  • Chromosomal Instability 50%
  5 被引用数 (Scopus)
• 2018

  A new robotic-assisted flexible endoscope with single-hand control: endoscopic submucosal dissection in the ex vivo porcine stomach

  iwasa, T., Nakadate, R., Onogi, S., Okamoto, Y., Arata, J., Oguri, S., Ogino, H., Ihara, E., Ohuchida, K., Akahoshi, T., Ikeda, T., Ogawa, Y. & Hashizume, M., 7月 1 2018, In: Surgical endoscopy. 32, 7, p. 3386-3392 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Endoscope 100%
  • Endoscopic Submucosal Dissection 35%
  • Surgery 20%
  • Movement (Physiology) 15%
  • Ex Vivo 10%
  27 被引用数 (Scopus)

• A novel histological examination with dynamic three-dimensional reconstruction from multiple immunohistochemically stained sections of a PD-L1-positive colon cancer

  Korehisa, S., Ikeda, T., Okano, S., Saeki, H., Oki, E., Oda, Y., Hashizume, M. & Maehara, Y., 3月 2018, In: Histopathology. 72, 4, p. 697-703 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Programmed Cell Death 100%
  • Ligand 100%
  • Cells 60%
  • Colon Cancer 60%
  • Microsatellite Instability 40%
  11 被引用数 (Scopus)

• Antithrombin III for portal vein thrombosis in patients with liver disease: A randomized, double-blind, controlled trial

  The NPB-06 study group, 2月 2018, In: Hepatology Research. 48, 3, p. E107-E116

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Patient 100%
  • Antithrombin III 72%
  • Portal Vein Thrombosis 45%
  • Liver Disease 27%
  • Coagulation 27%
  29 被引用数 (Scopus)

• Catumaxomab with activated T-cells efficiently lyses chemoresistant EpCAM-positive triple-negative breast cancer cell lines

  Kubo, M., Umebayashi, M., Kurata, K., Mori, H., Kai, M., Onishi, H., Katano, M., Nakamura, M. & Morisaki, T., 7月 2018, In: Anticancer research. 38, 7, p. 4273-4279 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Epithelial Cell Adhesion Molecule 100%
  • T Cell 71%
  • Triple Negative Breast Cancer 71%
  • Cancer Cell 57%
  • Catumaxomab 57%
  16 被引用数 (Scopus)

• Combined gemcitabine and metronidazole is a promising therapeutic strategy for cancer stem-like cholangiocarcinoma

  Kawamoto, M., Umebayashi, M., Tanaka, H., Koya, N., Nakagawa, S., Kawabe, K., Onishi, H., Nakamura, M. & Morisaki, T., 5月 2018, In: Anticancer research. 38, 5, p. 2739-2748 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Metronidazole 100%
  • Gemcitabine 66%
  • Cholangiocarcinoma 55%
  • Bile Duct Carcinoma 55%
  • Malignant Neoplasm 44%
  12 被引用数 (Scopus)

• Customization of laparoscopic gastric devascularization and splenectomy for gastric varices based on CT vascular anatomy

  Kawanaka, H., Akahoshi, T., Nagao, Y., Kinjo, N., Yoshida, D., Matsumoto, Y., Harimoto, N., Itoh, S., Yoshizumi, T. & Maehara, Y., 1月 1 2018, In: Surgical endoscopy. 32, 1, p. 114-126 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Splenectomy 100%
  • Devascularization 100%
  • Patient 75%
  • Stomach Varices 75%
  • Vein 50%
  4 被引用数 (Scopus)

• Dispatcher-assisted bystander cardiopulmonary resuscitation and survival in out-of-hospital cardiac arrest

  Hagihara, A., Onozuka, D., Shibuta, H., Hasegawa, M. & Nagata, T., 4月 19 2018, (印刷前の電子出版) In: International Journal of Cardiology.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Resuscitation 100%
  • Survival 77%
  • Out of Hospital Cardiac Arrest 66%
  • Patient 44%
  • Odds Ratio 44%
  13 被引用数 (Scopus)

• Effect of early treatment on physical function in daily management of rheumatoid arthritis: A 5-year longitudinal study of rheumatoid arthritis patients in the national database of rheumatic diseases in Japan

  Hirata, A., Suenaga, Y., Miyamura, T., Matsui, T., Tohma, S., Suematsu, E., Ohnaka, K. & Takayanagi, R., 2018, In: International Journal of Rheumatic Diseases. 21, 4, p. 828-835 8 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Patient 100%
  • Rheumatoid Arthritis 58%
  • Biological Product 50%
  • Health Assessment Questionnaire 41%
  • Methotrexate 33%
  4 被引用数 (Scopus)

• Feasibility of an AI-Based Measure of the Hand Motions of Expert and Novice Surgeons

  Uemura, M., Tomikawa, M., Miao, T., Souzaki, R., Ieiri, S., Akahoshi, T., Lefor, A. K. & Hashizume, M., 2018, In: Computational and Mathematical Methods in Medicine. 2018, 9873273.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Surgeon 100%
  • Skill 50%
  • Decision Making 25%
  • Intelligence 25%
  • Assessment 12%
  23 被引用数 (Scopus)