先端医療医学部門

研究成果 1980 2019

フィルター
記事
2019

2,5-Dimethylcelecoxib prevents isoprenaline-induced cardiomyocyte hypertrophy and cardiac fibroblast activation by inhibiting Akt-mediated GSK-3 phosphorylation

Morishige, S., Takahashi-Yanaga, F., Ishikane, S., arioka, M., Igawa, K., Kuroo, A., Tomooka, K., Shiose, A. & Sasaguri, T., 10 1 2019, : : Biochemical Pharmacology. 168, p. 82-90 9 p.

研究成果: ジャーナルへの寄稿記事

Glycogen Synthase Kinase 3
Phosphorylation
Cardiomegaly
Fibroblasts
Isoproterenol

A case of acute exacerbation of chronic adrenal insufficiency due to ipilimumab treatment for advanced melanoma

Sakaguchi, C., Yano, S., Ashida, K., Wada, N., Ohe, K., Nagata, H., matsuda, Y., Sakamoto, S., Sakamoto, R., Keizo, O., Hiroshi, U., Furue, M., Nomura, M. & Ogawa, Y., 1 1 2019, : : American Journal of Case Reports. 20, p. 106-110 5 p.

研究成果: ジャーナルへの寄稿記事

Adrenal Insufficiency
Melanoma
Therapeutics
Programmed Cell Death 1 Receptor
ipilimumab
1 引用 (Scopus)
公開
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Diabetic Retinopathy
Hypercholesterolemia
LDL Cholesterol
Therapeutics

Architecture of the Japan ischemic heart disease multimodal prospective data acquisition for precision treatment (J-IMPACT) system

Matoba, T., Kohro, T., Fujita, H., Nakayama, M., Kiyosue, A., Miyamoto, Y., Nishimura, K., Hashimoto, H., Antoku, Y., Nakashima, N., Ohe, K., Ogawa, H., Tsutsui, H. & Nagai, R., 1 1 2019, : : International heart journal. 60, 2, p. 264-270 7 p.

研究成果: ジャーナルへの寄稿記事

公開
Percutaneous Coronary Intervention
Myocardial Ischemia
Japan
Coronary Angiography
Information Systems

Assessment of coronary flow velocity reserve in the left main trunk using phase-contrast MR imaging at 3T: Comparison with 15O-labeled water positron emission tomography

Kikuchi, Y., Naya, M., Manabe, N. O., Manabe, O., Sugimori, H., Kudo, K., Kato, F., Aikawa, T., Tsutsui, H., Tamaki, N. & Shirato, H., 1 1 2019, : : Magnetic Resonance in Medical Sciences. 18, 2, p. 134-141 8 p.

研究成果: ジャーナルへの寄稿記事

公開
Positron-Emission Tomography
Coronary Artery Disease
Water
Arteries
Contrast Media

Baseline demographics and clinical characteristics in the all nippon af in the elderly (ANAFIE) registry

Koretsune, Y., Yamashita, T., Akao, M., Atarashi, H., Ikeda, T., Okumura, K., Shimizu, W., Tsutsui, H., Toyoda, K., Hirayama, A., Yasaka, M., Yamaguchi, T., Teramukai, S., Kimura, T., Kaburagi, J., Takita, A. & Inoue, H., 1 1 2019, : : Circulation Journal. 83, 7, p. 1538-1545 8 p.

研究成果: ジャーナルへの寄稿記事

公開
Registries
Demography
Anticoagulants
Atrial Fibrillation
Prospective Studies
Purkinje Fibers
Catheter Ablation
Ventricular Tachycardia
Verapamil
Electrodes

Colorectal endoscopic submucosal dissection using novel articulating devices: a comparative study in a live porcine model

Okamoto, Y., Nakadate, R., Nakamura, S., Arata, J., Oguri, S., Tomohiko, M., Esaki, M., iwasa, T., Ouchida, K., Akahoshi, T., Ikeda, T., Kitazono, T. & Hashizume, M., 2 15 2019, : : Surgical endoscopy. 33, 2, p. 651-657 7 p.

研究成果: ジャーナルへの寄稿記事

Swine
Equipment and Supplies
Endoscopic Mucosal Resection
Anal Canal
Colon
公開
Aortic Valve
Surgical Instruments
Pressure
Stroke
Stroke Volume

Congenitally Corrected Transposition of the Great Arteries( TGA) in Adult

Tatewaki, H., Sakamoto, I., Hirayama, K. & Shiose, A., 4 1 2019, : : Kyobu geka. The Japanese journal of thoracic surgery. 72, 4, p. 269-274 6 p.

研究成果: ジャーナルへの寄稿記事

Heart Ventricles
Tricuspid Valve
Ventricular Heart Septal Defects
Reoperation
Pulmonary Artery
Mandibular Advancement
Obstructive Sleep Apnea
Blood Pressure
Equipment and Supplies
Sleep

Diabetes mellitus attenuates the pressure response against hypotensive stress by impairing the sympathetic regulation of the baroreflex afferent arc

Kamada, K., Saku, K., Tohyama, T., Kawada, T., Mannoji, H., Abe, K., Nishikawa, T., Sunagawa, G., Kishi, T., Sunagawa, K. & Tsutsui, H., 1 1 2019, : : American Journal of Physiology - Heart and Circulatory Physiology. 316, 1, p. H35-H44

研究成果: ジャーナルへの寄稿記事

Baroreflex
Diabetes Mellitus
Arterial Pressure
Pressure
Type 2 Diabetes Mellitus
Heart-Assist Devices
Suction
Transplants
2 引用 (Scopus)

Early therapeutic effects of adaptive servo-ventilation on cardiac sympathetic nervous function in patients with heart failure evaluated using a combination of 11C-HED PET and 123I-MIBG SPECT

Tokuda, Y., Sakakibara, M., Yoshinaga, K., Yamada, S., Kamiya, K., Asakawa, N., Yoshitani, T., Noguchi, K., Manabe, O., Tamaki, N. & Tsutsui, H., 8 15 2019, : : Journal of Nuclear Cardiology. 26, 4, p. 1079-1089 11 p.

研究成果: ジャーナルへの寄稿記事

Therapeutic Uses
Single-Photon Emission-Computed Tomography
Ventilation
Heart Failure
Brain Natriuretic Peptide
Vasodilator Agents
Nitrates
Heart Failure
Databases
Hospitalization
1 引用 (Scopus)

Effects of coronary revascularization on global coronary flow reserve in stable coronary artery disease

Aikawa, T., Naya, M., Obara, M., Manabe, O., Magota, K., Koyanagawa, K., Asakawa, N., Ito, Y. M., Shiga, T., Katoh, C., Anzai, T., Tsutsui, H., Murthy, V. L. & Tamaki, N., 1 1 2019, : : Cardiovascular research. 115, 1, p. 119-129 11 p.

研究成果: ジャーナルへの寄稿記事

Coronary Artery Bypass
Percutaneous Coronary Intervention
Coronary Artery Disease
Positron-Emission Tomography
Multicenter Studies

Elevated non-invasive liver fibrosis markers and risk of liver carcinoma in adult patients after repair of tetralogy of Fallot

Yamamura, K., Sakamoto, I., Morihana, E., Hirata, Y., Nagata, H., Yamasaki, Y., Okumura, Y., Kouhashi, K., Koto, K., Tsutsui, H. & Ohga, S., 7 15 2019, : : International Journal of Cardiology. 287, p. 121-126 6 p.

研究成果: ジャーナルへの寄稿記事

Tetralogy of Fallot
Liver Cirrhosis
Carcinoma
Liver
Hyaluronic Acid
1 引用 (Scopus)

Estimation of the baroreflex total loop gain by the power spectral analysis of continuous arterial pressure recordings

Mannoji, H., Saku, K., Nishikawa, T., Tohyama, T., Kamada, K., Abe, K., Sunagawa, G., Kishi, T., Sunagawa, K. & Tsutsui, H., 4 1 2019, : : American Journal of Physiology - Heart and Circulatory Physiology. 316, 4, p. H828-H839

研究成果: ジャーナルへの寄稿記事

Baroreflex
Arterial Pressure
Denervation
Pressure
Carotid Sinus
公開
Heart-Assist Devices
Thrombosis
Transplants
Architectural Accessibility
Heart Failure
3 引用 (Scopus)

Heart failure with reduced ejection fraction: comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas

Dewan, P., Jhund, P. S., Shen, L., Petrie, M. C., Abraham, W. T., Atif Ali, M., Chen, C. H., Desai, A. S., Dickstein, K., Huang, J., Kiatchoosakun, S., Kim, K. S., Køber, L., Lai, W. T., Liao, Y., Mogensen, U. M., Oh, B. H., Packer, M., Rouleau, J. L., Shi, V. および7人, Sibulo, A. S., Solomon, S. D., Sritara, P., Swedberg, K., Tsutsui, H., Zile, M. R. & McMurray, J. J. V., 5 1 2019, : : European Journal of Heart Failure. 21, 5, p. 577-587 11 p.

研究成果: ジャーナルへの寄稿記事

公開
Heart Failure
North America
Philippines
China
Taiwan

Hospitalization costs for patients with acute congestive heart failure in Japan

Kanaoka, K., Okayama, S., Nakai, M., Sumita, Y., Nishimura, K., Kawakami, R., Okura, H., Miyamoto, Y., Yasuda, S., Tsutsui, H., Komuro, I., Ogawa, H. & Saito, Y., 1 1 2019, : : Circulation Journal. 83, 5, p. 1025-1031 7 p.

研究成果: ジャーナルへの寄稿記事

公開
Japan
Hospitalization
Heart Failure
Costs and Cost Analysis
Acute Disease

Hypoxia-inducible factor-1 α deletion in myeloid lineage attenuates hypoxia-induced pulmonary hypertension

Kojima, H., Tokunou, T., Takahara, Y., Sunagawa, K., Hirooka, Y., Ichiki, T. & Tsutsui, H., 4 1 2019, : : Physiological Reports. 7, 7, e14025.

研究成果: ジャーナルへの寄稿記事

公開
Hypoxia-Inducible Factor 1
Pulmonary Hypertension
Knockout Mice
Lung
Macrophages
1 引用 (Scopus)

Implication of preoperative existence of atrial fibrillation on hemocompatibility-related adverse events during left ventricular assist device support

Imamura, T., Kinugawa, K., Ono, M., Kinoshita, O., Fukushima, N., Shiose, A., Matsui, Y., Yamazaki, K., Saiki, Y., Usui, A., Niinami, H., Matsumiya, G., Arai, H. & Sawa, Y., 1 1 2019, : : Circulation Journal. 83, 6, p. 1286-1292 7 p.

研究成果: ジャーナルへの寄稿記事

公開
Heart-Assist Devices
Atrial Fibrillation
Propensity Score
Registries
Thrombosis

Inhibition of TLR9-NF-κB-mediated sterile inflammation improves pressure overload-induced right ventricular dysfunction in rats

Yoshida, K., Abe, K., Ishikawa, M., Saku, K., Shinoda-Sakamoto, M., Ishikawa, T., Watanabe, T., Oka, M., Sunagawa, K. & Tsutsui, H., 3 1 2019, : : Cardiovascular research. 115, 3, p. 658-668 11 p.

研究成果: ジャーナルへの寄稿記事

Toll-Like Receptor 9
Right Ventricular Dysfunction
Pulmonary Artery
Inflammation
Pressure

Involvement of different receptor subtypes in prostaglandin E2-induced contraction and relaxation in the lower esophageal sphincter and esophageal body

Bai, X., Ihara, E., Otsuka, Y., Tsuruta, S., Hirano, K., Tanaka, Y., Ogino, H., Hirano, M., Chinen, T., Akiho, H., Nakamura, K., Oda, Y. & Ogawa, Y., 8 15 2019, : : European Journal of Pharmacology. 857, 172405.

研究成果: ジャーナルへの寄稿記事

Lower Esophageal Sphincter
Dinoprostone
Smooth Muscle
Gastroesophageal Reflux
Muscle Contraction

Japanese periodical nationwide epidemiologic survey of aberrant portal hemodynamics

Ohfuji, S., Furuichi, Y., Akahoshi, T., Kage, M., Obara, K., Hashizume, M., Matsuura, T., Fukushima, W. & Nakamura, Y., 1 1 2019, : : Hepatology Research.

研究成果: ジャーナルへの寄稿記事

公開
Hemodynamics
Japan
Pediatrics
Epidemiologic Methods
Surveys and Questionnaires

Jarvik 2000 axial flow ventricular assist device in right single ventricle after Fontan operation

Tanoue, Y., Fujino, T., Tatewaki, H. & Shiose, A., 1 1 2019, (受理済み/印刷中) : : Journal of Artificial Organs.

研究成果: ジャーナルへの寄稿記事

Artificial organs
Fontan Procedure
Heart-Assist Devices
Axial flow
Heart Ventricles
1 引用 (Scopus)

JCS 2018 guideline on diagnosis and treatment of acute coronary syndrome

on behalf of the Japanese Circulation Society Joint Working Group, 1 1 2019, : : Circulation Journal. 83, 5, p. 1085-1196 112 p.

研究成果: ジャーナルへの寄稿記事

公開
Acute Coronary Syndrome
Guidelines

Liprin-α4 as a new therapeutic target for SCLC as an upstream mediator of HIF1α

Ohnishi, H., Yamasaki, A., Nakamura, K., Ichimiya, S., Yanai, K., Umebayashi, M., Nagai, S. & Morisaki, T., 3 1 2019, : : Anticancer research. 39, 3, p. 1179-1184 6 p.

研究成果: ジャーナルへの寄稿記事

Small Cell Lung Carcinoma
Cell Hypoxia
Cisplatin
CD45 Antigens
Hypoxia-Inducible Factor 1
3 引用 (Scopus)

Mechano-chronotropic Unloading During the Acute Phase of Myocardial Infarction Markedly Reduces Infarct Size via the Suppression of Myocardial Oxygen Consumption

Sunagawa, G., Saku, K., Arimura, T., Nishikawa, T., Mannoji, H., Kamada, K., Abe, K., Kishi, T., Tsutsui, H. & Sunagawa, K., 4 15 2019, : : Journal of Cardiovascular Translational Research. 12, 2, p. 124-134 11 p.

研究成果: ジャーナルへの寄稿記事

ivabradine
Oxygen Consumption
Myocardial Infarction
Ischemia
Reperfusion

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J-I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., 6 1 2019, : : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

研究成果: ジャーナルへの寄稿記事

Myocardial Reperfusion Injury
Toll-Like Receptor 4
Reperfusion Injury
Nanoparticles
Myocardial Ischemia

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J. I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., 6 1 2019, : : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

研究成果: ジャーナルへの寄稿記事

公開
Myocardial Reperfusion Injury
Toll-Like Receptor 4
Reperfusion Injury
Nanoparticles
Myocardial Ischemia

Nationwide survey of multidisciplinary care and cardiac rehabilitation for patients with heart failure in Japan ― An analysis of the AMED-CHF study ―

Kamiya, K., Yamamoto, T., Tsuchihashi-Makaya, M., Ikegame, T., Takahashi, T., Sato, Y., Kotooka, N., Saito, Y., Tsutsui, H., Miyata, H. & Isobe, M., 1 1 2019, : : Circulation Journal. 83, 7, p. 1546-1552 7 p.

研究成果: ジャーナルへの寄稿記事

公開
Japan
Heart Failure
Outpatients
Inpatients
Cardiac Rehabilitation

Non-Pulmonary Vein Triggers of Atrial Fibrillation Are Likely to Arise from Low-Voltage Areas in the Left Atrium

Kawai, S., Mukai, Y., Inoue, S., Yakabe, D., Nagaoka, K., Sakamoto, K., Takase, S., Chishaki, A. & Tsutsui, H., 12 1 2019, : : Scientific reports. 9, 1, 12271.

研究成果: ジャーナルへの寄稿記事

公開
Heart Atria
Atrial Fibrillation
Veins
Catheter Ablation

Pancreatic Juice Exosomal MicroRNAs as Biomarkers for Detection of Pancreatic Ductal Adenocarcinoma

Nakamura, S., Sadakari, Y., Takao, O., Okayama, T., Nakashima, Y., Gotoh, Y., Saeki, K., Mori, Y., Nakata, K., Miyasaka, Y., Ohnishi, H., Oda, Y., Goggins, M. & Nakamura, M., 7 15 2019, : : Annals of Surgical Oncology. 26, 7, p. 2104-2111 8 p.

研究成果: ジャーナルへの寄稿記事

Pancreatic Juice
MicroRNAs
Adenocarcinoma
Biomarkers
Exosomes

Pectoral Muscle Atrophy After Axillary Artery Cannulation for Aortic Arch Surgery

Imasaka, K. I., Tomita, Y., Nishijima, T., Tayama, E., Morita, S., Toriya, R. & Shiose, A., 1 1 2019, : : Seminars in Thoracic and Cardiovascular Surgery.

研究成果: ジャーナルへの寄稿記事

Axillary Artery
Pectoralis Muscles
Muscular Atrophy
Thoracic Aorta
Catheterization
Myocarditis
Thrombosis
Pediatrics
Equipment and Supplies
Extracorporeal Membrane Oxygenation
3 引用 (Scopus)

Peroxisome proliferator-activated receptor-gamma targeting nanomedicine promotes cardiac healing after acute myocardial infarction by skewing monocyte/macrophage polarization in preclinical animal models

Tokutome, M., Matoba, T., Nakano, Y., Okahara, A., Fujiwara, M., Koga, J. I., Nakano, K., Tsutsui, H. & Egashira, K., 2 1 2019, : : Cardiovascular research. 115, 2, p. 419-431 13 p.

研究成果: ジャーナルへの寄稿記事

pioglitazone
Nanomedicine
PPAR gamma
Monocytes
Animal Models

Possible associations between palliative care conferences and positive outcomes when performing palliative care for patients with end-stage heart failure: a nationwide cross-sectional questionnaire survey

Kurozumi, Y., Oishi, S., Sugano, Y., Sakashita, A., Kotooka, N., Suzuki, M., Higo, T., Yumino, D., Takada, Y., Maeda, S., Yamabe, S., Washida, K., Takahashi, T., Ohtani, T., Sakata, Y. & Sato, Y., 3 15 2019, : : Heart and Vessels. 34, 3, p. 452-461 10 p.

研究成果: ジャーナルへの寄稿記事

Palliative Care
Heart Failure
Cross-Sectional Studies
Nutritionists
Surveys and Questionnaires

Predictive value of the induction test with atrial burst pacing with regard to long-term recurrence after ablation in persistent atrial fibrillation

Kawai, S., Mukai, Y., Inoue, S., Yakabe, D., Nagaoka, K., Sakamoto, K., Takase, S., Chishaki, A. & Tsutsui, H., 1 1 2019, (受理済み/印刷中) : : journal of arrhythmia.

研究成果: ジャーナルへの寄稿記事

Predictive Value of Tests
Atrial Fibrillation
Tachycardia
Recurrence
Catheter Ablation

Prescription rates of guideline-directed medications are associated with in-hospital mortality among Japanese patients with acute myocardial infarction: A report from JROAD-DPC study

Nakao, K., Yasuda, S., Nishimura, K., Noguchi, T., Nakai, M., Miyamoto, Y., Sumita, Y., Shishido, T., Anzai, T., Ito, H., Tsutsui, H., Saito, Y., Komuro, I. & Ogawa, H., 1 1 2019, : : Journal of the American Heart Association. 8, 7, e009692.

研究成果: ジャーナルへの寄稿記事

公開
Hospital Mortality
Prescriptions
Myocardial Infarction
Guidelines
Peptidyl-Dipeptidase A

Primary percutaneous coronary intervention in elderly patients with acute myocardial infarction — An analysis from a Japanese nationwide claim-based database

Uemura, S., Okamoto, H., Nakai, M., Nishimura, K., Miyamoto, Y., Yasuda, S., Tanaka, N., Kohsaka, S., Kadota, K., Saito, Y., Tsutsui, H., Komuro, I., Ikari, Y., Ogawa, H. & Nakamura, M., 1 1 2019, : : Circulation Journal. 83, 6, p. 1229-1238 10 p.

研究成果: ジャーナルへの寄稿記事

公開
Percutaneous Coronary Intervention
Myocardial Infarction
Databases
Mortality
Propensity Score

Primary pericardial mesothelioma presenting as constrictive pericarditis

Yamamoto, T., Ohtani, K., Tanoue, Y., Shiose, A. & Tsutsui, H., 5 1 2019, : : European heart journal cardiovascular Imaging. 20, 5, 1 p.

研究成果: ジャーナルへの寄稿記事

Constrictive Pericarditis
Mesothelioma
2 引用 (Scopus)

Proteinase-activated receptor 1 antagonism ameliorates experimental pulmonary hypertension

Kuwabara, Y., Tanaka-Ishikawa, M., Abe, K., Hirano, M., Hirooka, Y., Tsutsui, H., Sunagawa, K. & Hirano, K., 7 1 2019, : : Cardiovascular research. 115, 8, p. 1357-1368 12 p.

研究成果: ジャーナルへの寄稿記事

公開
PAR-1 Receptor
Pulmonary Hypertension
Monocrotaline
Pulmonary Artery
Right Ventricular Hypertrophy
1 引用 (Scopus)
Anthracyclines
Left Ventricular Dysfunction
Heart Failure
Treatment Failure
Neoplasms

Simple risk score to predict survival in acute decompensated heart failure: A2B score

Nakada, Y., Kawakami, R., Matsushima, S., Ide, T., Kanaoka, K., Ueda, T., Ishihara, S., Nishida, T., Onoue, K., Soeda, T., Okayama, S., Watanabe, M., Okura, H., Tsuchihashi-Makaya, M., Tsutsui, H. & Saito, Y., 1 1 2019, : : Circulation Journal. 83, 5, p. 1019-1024 6 p.

研究成果: ジャーナルへの寄稿記事

公開
Heart Failure
Survival
Patient Discharge
Brain Natriuretic Peptide
Hemoglobins
Aneurysm
Perfusion
Thorax
Endoleak
Vocal Cord Paralysis

Suppressed baroreflex peripheral arc overwhelms augmented neural arc and incapacitates baroreflex function in rats with pulmonary arterial hypertension

Shinoda, M., Saku, K., Oga, Y., Tohyama, T., Nishikawa, T., Abe, K., Yoshida, K., Kuwabara, Y., Fujii, K., Ishikawa, T., Kishi, T., Sunagawa, K. & Tsutsui, H., 1 1 2019, : : Experimental Physiology.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Pulmonary Hypertension
Monocrotaline
Arterial Pressure
Pressure

Thoracic endografting increases cardiac afterload and leads to left ventricular hypertrophy in dogs

Yamashita, Y., Oishi, Y., Motomatsu, Y., Hirayama, K., Harada, T., Ushijima, T., fujita, S., Kimura, S., Sonoda, H., Tatewaki, H., Tanoue, Y., Sunagawa, G., Nishikawa, T., Saku, K. & Shiose, A., 4 1 2019, : : European Journal of Cardio-thoracic Surgery. 55, 4, p. 618-625 8 p.

研究成果: ジャーナルへの寄稿記事

Left Ventricular Hypertrophy
Electric Impedance
Thorax
Dogs
Cardiac Myocytes