基礎医学部門

研究成果 1980 2019

2019

2,5-Dimethylcelecoxib prevents isoprenaline-induced cardiomyocyte hypertrophy and cardiac fibroblast activation by inhibiting Akt-mediated GSK-3 phosphorylation

Morishige, S., Takahashi-Yanaga, F., Ishikane, S., arioka, M., Igawa, K., Kuroo, A., Tomooka, K., Shiose, A. & Sasaguri, T., 10 1 2019, : : Biochemical Pharmacology. 168, p. 82-90 9 p.

研究成果: ジャーナルへの寄稿記事

Celecoxib
Glycogen Synthase Kinase 3
Phosphorylation
Cardiomegaly
Fibroblasts

A case of autonomous cortisol secretion in a patient with subclinical Cushing's syndrome, GNAS mutation, and paradoxical cortisol response to dexamethasone

Sakaguchi, C., Ashida, K., Kouhashi, K., Ohe, K., Fujii, Y., Yano, S., matsuda, Y., Sakamoto, S., Sakamoto, R., Oda, Y., Nomura, M. & Ogawa, Y., 1 22 2019, : : BMC Endocrine Disorders. 19, 1, 13.

研究成果: ジャーナルへの寄稿記事

Cushing Syndrome
Dexamethasone
Hydrocortisone
Mutation
Oral Administration

aCGH Analysis of Predictive Biomarkers for Response to Bevacizumab plus Oxaliplatin- or Irinotecan-Based Chemotherapy in Patients with Metastatic Colorectal Cancer

Fujita, Y., Taguri, M., Yamazaki, K., Tsurutani, J., Sakai, K., Tsushima, T., Nagase, M., Tamagawa, H., Ueda, S., Tamura, T., Tsuji, Y., Murata, K., Taira, K., Denda, T., Moriwaki, T., Funai, S., Nakajima, T. E., Muro, K., Tsuji, A., Yoshida, M. および11人Suyama, K., Kurimoto, T., Sugimoto, N., Baba, E., Seki, N., Sato, M., Shimura, T., Boku, N., Hyodo, I., Yamanaka, T. & Nishio, K., 3 1 2019, : : Oncologist. 24, 3, p. 327-337 11 p.

研究成果: ジャーナルへの寄稿記事

irinotecan
oxaliplatin
Comparative Genomic Hybridization
Colorectal Neoplasms
Biomarkers
1 引用 (Scopus)

A Clinicopathological and Prognostic Analysis of PD-L2 Expression in Surgically Resected Primary Lung Squamous Cell Carcinoma

Matsubara, T., Takada, K., Azuma, K., Takamori, S., Toyokawa, G., Haro, A., Osoegawa, A., Tagawa, T., Kawahara, A., Akiba, J., Okamoto, I., Nakanishi, Y., Oda, Y., Hoshino, T. & Maehara, Y., 6 15 2019, : : Annals of Surgical Oncology. 26, 6, p. 1925-1933 9 p.

研究成果: ジャーナルへの寄稿記事

Squamous Cell Carcinoma
Ligands
Lung
CD274 Antigen
Immunotherapy

A highly efficient method for concentrating DNA from river water by combined coagulation and foam separation

Suzuki, Y., Imafuku, Y., Nishiyama, M., Teranishi, K., Jikumaru, A., Nukazawa, K. & Ogura, Y., 1 1 2019, (受理済み/印刷中) : : Separation Science and Technology (Philadelphia).

研究成果: ジャーナルへの寄稿記事

Coagulation
Foams
DNA
Rivers
Water

Analysis of systemic lupus erythematosus-related interstitial pneumonia: a retrospective multicentre study

Enomoto, N., Egashira, R., Tabata, K., Hashisako, M., Kitani, M., Waseda, Y., Ishizuka, T., Watanabe, S., Kasahara, K., Izumi, S., Shiraki, A., Miyamoto, A., Kishi, K., Kishaba, T., Sugimoto, C., Inoue, Y., Kataoka, K., Kondoh, Y., Tsuchiya, Y., Baba, T. および4人Sugiura, H., Tanaka, T., Sumikawa, H. & Suda, T., 12 1 2019, : : Scientific reports. 9, 1, 7355.

研究成果: ジャーナルへの寄稿記事

公開
Interstitial Lung Diseases
Systemic Lupus Erythematosus
Multicenter Studies
Retrospective Studies
Tomography

Arsenate and microbial dynamics in different phosphorus regimes of the subtropical Pacific Ocean

Hashihama, F., Suwa, S., Kanda, J., Ehama, M., Sakuraba, R., Kinouchi, S., Sato, M., Yamaguchi, T., Saito, H., Ogura, Y., Hayashi, T., Mori, H., Kurokawa, K., Suzuki, S. & Hamasaki, K., 9 1 2019, : : Progress in Oceanography. 176, 102115.

研究成果: ジャーナルへの寄稿記事

arsenates
arsenate
Pacific Ocean
phosphate
phosphates

A simple method for semi-automatic readjustment for positioning in post-mortem head computed tomography imaging

Kawazoe, Y., Morishita, J., Matsunobu, Y., Okumura, M., Shin, S., Usumoto, Y. & Ikeda, N., 3 1 2019, : : Journal of Forensic Radiology and Imaging. 16, p. 57-64 8 p.

研究成果: ジャーナルへの寄稿記事

Head
Tomography
Yaws

Association between peripheral blood markers and immune-related factors on tumor cells in patients with resected primary lung adenocarcinoma

Takada, K., Shimokawa, M., Tanaka, K., Kouhashi, K., Haro, A., Osoegawa, A., Tagawa, T., Azuma, K., Okamoto, I., Oda, Y. & Mori, M., 6 1 2019, : : PloS one. 14, 6, e0217991.

研究成果: ジャーナルへの寄稿記事

公開
Indoleamine-Pyrrole 2,3,-Dioxygenase
Immunologic Factors
adenocarcinoma
Cell death
Tumors
1 引用 (Scopus)

Association of Missense Polymorphism in HSD3B1 With Outcomes Among Men With Prostate Cancer Treated With Androgen-Deprivation Therapy or Abiraterone

shiota, M., Narita, S., Akamatsu, S., Fujimoto, N., Sumiyoshi, T., Fujiwara, M., Uchiumi, T., Habuchi, T., Ogawa, O. & Eto, M., 2 1 2019, : : JAMA network open. 2, 2, p. e190115

研究成果: ジャーナルへの寄稿記事

公開
Androgens
Prostatic Neoplasms
Odds Ratio
Therapeutics
Castration

BspR/BtrA, an Anti-σ Factor, Regulates the Ability of Bordetella bronchiseptica To Cause Cough in Rats

Nakamura, K., Shinoda, N., Hiramatsu, Y., Ohnishi, S., Kamitani, S., Ogura, Y., Hayashi, T. & Horiguchi, Y., 4 24 2019, : : mSphere. 4, 2

研究成果: ジャーナルへの寄稿記事

公開
Bordetella bronchiseptica
Cough
Bordetella pertussis
Bordetella Infections
Bordetella

Budding Uninhibited by Benzimidazole-1 Insufficiency Prevents Acute Renal Failure in Severe Sepsis by Maintaining Anticoagulant Functions of Vascular Endothelial Cells

Matsubara, Y., Matsumoto, T., Yoshiya, K., Yoshida, A., Ikeda, S., Furuyama, T., Nakatsu, Y., Tsuzuki, T., Nomura, M. & Maehara, Y., 3 1 2019, : : Shock (Augusta, Ga.). 51, 3, p. 364-371 8 p.

研究成果: ジャーナルへの寄稿記事

Acute Kidney Injury
Anticoagulants
Sepsis
Endothelial Cells
Thrombomodulin
Androgen Antagonists
Androgen Receptors
docetaxel
Prostatic Neoplasms
Smoking
2 引用 (Scopus)

Co-expression of IDO1 and PD-L1 in lung squamous cell carcinoma: Potential targets of novel combination therapy

Takada, K., Kouhashi, K., Shimokawa, M., Haro, A., Osoegawa, A., Tagawa, T., Seto, T., Oda, Y. & Maehara, Y., 2 1 2019, : : Lung Cancer. 128, p. 26-32 7 p.

研究成果: ジャーナルへの寄稿記事

CD274 Antigen
Indoleamine-Pyrrole 2,3,-Dioxygenase
Squamous Cell Carcinoma
Lung
Therapeutics

Consensus and variations in cell line specificity among human metapneumovirus strains

Nao, N., Sato, K., Yamagishi, J., Tahara, M., Nakatsu, Y., Seki, F., Katoh, H., Ohnuma, A., Shirogane, Y., Hayashi, M., Suzuki, T., Kikuta, H., Nishimura, H. & Takeda, M., 4 1 2019, : : PloS one. 14, 4, e0215822.

研究成果: ジャーナルへの寄稿記事

公開
Human metapneumovirus
Metapneumovirus
Cells
cell lines
Cell Line
1 引用 (Scopus)

Cooperation between different variants: A unique potential for virus evolution

Shirogane, Y., Watanabe, S. & Yanagi, Y., 4 15 2019, : : Virus Research. 264, p. 68-73 6 p.

研究成果: ジャーナルへの寄稿評論記事

Genome
Viruses
Defective Viruses
Immune Evasion
RNA Replicase
Limbic Encephalitis
Voltage-Gated Potassium Channels
Creutzfeldt-Jakob Syndrome
Antibodies
Cuprizone
Phytoestrogens
Genistein
Demyelinating Diseases
Hippocampus

Dairy consumption and risk of functional disability in an elderly Japanese population: The Hisayama Study

Yoshida, D., Ohara, T., Hata, J., Shibata, M., Hirakawa, Y., Honda, T., Uchida, K., Takasugi, S., Kitazono, T., Kiyohara, Y. & Ninomiya, T., 6 1 2019, : : American Journal of Clinical Nutrition. 109, 6, p. 1664-1671 8 p.

研究成果: ジャーナルへの寄稿記事

Activities of Daily Living
Population
Independent Living
Geriatrics
Mental Competency

Diagnostic challenge of the newborn patients with heritable protein C deficiency

Ichiyama, M., Inoue, H., Ochiai, M., ishimura, M., Shiraishi, A., Fujiyoshi, J., Yamashita, H., Sato, K., Matsumoto, S., Hotta, T., Uchiumi, T., Kang, D. & Ohga, S., 2 1 2019, : : Journal of Perinatology. 39, 2, p. 212-219 8 p.

研究成果: ジャーナルへの寄稿記事

Protein C Deficiency
Protein C
Protein S
Newborn Infant
Mutation

Differential genomic destabilisation in human cells with pathogenic MSH2 mutations introduced by genome editing

Hayashida, G., Shioi, S., Hidaka, K., Fujikane, R., Hidaka, M., Tsurimoto, T., Tsuzuki, T., Oda, S. & Nakatsu, Y., 4 15 2019, : : Experimental Cell Research. 377, 1-2, p. 24-35 12 p.

研究成果: ジャーナルへの寄稿記事

公開
Microsatellite Instability
DNA Mismatch Repair
Mutation
Microsatellite Repeats
Hereditary Nonpolyposis Colorectal Neoplasms

Draft genome sequence of mycolicibacterium sp. strain ncctsukiji, isolated from blood culture of a patient with malignant lymphoma

Fukano, H., Yoshida, M., Shouji, M., Hatta, S., Maruyama, D., Izutsu, K., Shiotsuka, M., Ogura, Y., Hayashi, T., Hasegawa, N., Iwata, S. & Hoshino, Y., 1 1 2019, : : Microbiology Resource Announcements. 8, 14, e01575-18.

研究成果: ジャーナルへの寄稿記事

公開
Multilocus Sequence Typing
Lymphoma
Genome
Blood Culture

Elevated non-invasive liver fibrosis markers and risk of liver carcinoma in adult patients after repair of tetralogy of Fallot

Yamamura, K., Sakamoto, I., Morihana, E., Hirata, Y., Nagata, H., Yamasaki, Y., Okumura, Y., Kouhashi, K., Koto, K., Tsutsui, H. & Ohga, S., 7 15 2019, : : International Journal of Cardiology. 287, p. 121-126 6 p.

研究成果: ジャーナルへの寄稿記事

Tetralogy of Fallot
Liver Cirrhosis
Carcinoma
Liver
Hyaluronic Acid

Evaluation of SNP calling methods for closely related bacterial isolates and a novel high-accuracy pipeline: BactSNP

Yoshimura, D., Kajitani, R., Gotoh, Y., Katahira, K., Okuno, M., Ogura, Y., Hayashi, T. & Itoh, T., 5 1 2019, : : Microbial Genomics. 5, 5

研究成果: ジャーナルへの寄稿記事

公開
Single Nucleotide Polymorphism
Genome
Benchmarking
Disease Outbreaks
Bacteria
Type 1 Diabetes Mellitus
Hypoglycemia
Pancreatitis
C-Peptide
Pancreas
Gyrus Cinguli
Alzheimer Disease
Temporal Lobe
Brain
Frontal Lobe

Genome sequencing verifies relapsed infection of helicobacter cinaedi

Sawada, O., Gotoh, Y., Taniguchi, T., Furukawa, S., Yoshimura, D., Sasaki, S., Shida, H., Kusunoki, Y., Yamamura, T., Furuya, K., Itoh, T., Horita, T., Hayashi, T. & Misawa, N., 1 1 2019, : : Open Forum Infectious Diseases. 6, 5

研究成果: ジャーナルへの寄稿記事

公開
Helicobacter Infections
Genome
Infection
Single Nucleotide Polymorphism
Clone Cells

Glypican-3 expression in malignant small round cell tumors

Shibui, Y., Miyoshi, K., Kouhashi, K., Kinoshita, Y., Kuda, M., Yamamoto, H., Taguchi, T. & Oda, Y., 3 1 2019, : : Oncology Letters. 17, 3, p. 3523-3528 6 p.

研究成果: ジャーナルへの寄稿記事

Glypicans
Neoplasms
Neuroblastoma
Ewing's Sarcoma
Desmoplastic Small Round Cell Tumor
Neuroendocrine Tumors
Neuroblastoma
Pheochromocytoma
Neoplasms
Ewing's Sarcoma

Identification of genomic alterations acquired during treatment with EGFR-TKIs in non-small cell lung cancer

Kubo, N., Harada, T., Shiraishi, Y., Nosaki, K., Nakagaki, N., Takeshita, M., Ouchi, H., Iwama, E., Tanaka, K., Okamoto, I., Sasaki, H. & Nakanishi, Y., 2 1 2019, : : Anticancer research. 39, 2, p. 671-677 7 p.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Therapeutics
Exome
公開
Genetic Polymorphisms
Caffeine
Healthy Volunteers
Heart Rate
Blood Pressure
Japan
Smoking
Health
Occupational Groups
Smoke-Free Policy

Intrahepatic cholangiocarcinoma after the Fontan procedure

Shibui, Y., Kouhashi, K., Sakamoto, I., Yamamura, K. & Oda, Y., 3 1 2019, : : Human Pathology: Case Reports. 15, p. 15-19 5 p.

研究成果: ジャーナルへの寄稿記事

Fontan Procedure
Cholangiocarcinoma
Liver Cirrhosis
Heart Failure
Liver

Lipase/Oxovanadium Co-Catalyzed Dynamic Kinetic Resolution of Propargyl Alcohols: Competition between Racemization and Rearrangement

Kawanishi, S., Oki, S., Kundu, D. & Akai, S., 5 3 2019, : : Organic Letters. 21, 9, p. 2978-2982 5 p.

研究成果: ジャーナルへの寄稿記事

Lipase
alcohols
Magic
Kinetics
Enantiomers

Local structural changes of the influenza A virus ribonucleoprotein complex by single mutations in the specific residues involved in efficient genome packaging

Takizawa, N., Ogura, Y., Fujita, Y., Noda, T., Shigematsu, H., Hayashi, T. & Kurokawa, K., 5 1 2019, : : Virology. 531, p. 126-140 15 p.

研究成果: ジャーナルへの寄稿記事

Ribonucleoproteins
Influenza A virus
Product Packaging
Genome
Viruses
Exercise
Population
Independent Living
Japan
Light

Meteorological effects on severe hemoptysis: A hospital-based observational study

Ogata, H., Matsumoto, K., Shinozaki, S., Hasegawa, M., Nakamura, S., Mizusaki, S., Takao, T., Nakatomi, K., Nakashima, N., Takahashi, K., Soeda, H., Hanada, K. & Koto, H., 1 1 2019, : : Respiratory Investigation.

研究成果: ジャーナルへの寄稿記事

Hemoptysis
Observational Studies
Humidity
Meteorological Concepts
Logistic Models

Mirabegron induces relaxant effects via cAMP signaling-dependent and -independent pathways in detrusor smooth muscle

Maki, T., Kajioka, S., Itsumi, M., Kareman, E., Lee, K., shiota, M. & Eto, M., 4 1 2019, : : LUTS: Lower Urinary Tract Symptoms. 11, 2, p. O209-O217

研究成果: ジャーナルへの寄稿記事

Smooth Muscle
Swine
Carbachol
Escin
Adrenergic Receptors
1 引用 (Scopus)

Multi-step genomic dissection of a suspected intra-hospital helicobacter cinaedi outbreak

Gotoh, Y., Taniguchi, T., Yoshimura, D., Katsura, K., Saeki, Y., Hirabara, Y., Fukuda, M., Takajo, I., Tomida, J., Kawamura, Y., Ogura, Y., Itoh, T., Misawa, N., Okayama, A. & Hayashi, T., 1 1 2019, : : Microbial Genomics. 5, 1, 000236.

研究成果: ジャーナルへの寄稿記事

Helicobacter
Disease Outbreaks
Dissection
Genome
Bacteremia
1 引用 (Scopus)

Navigation surgery using indocyanine green fluorescent imaging for hepatoblastoma patients

Sozaki, R., Kawakubo, N., Matsuura, T., Yoshimaru, K., Koga, Y., Takemoto, J., Shibui, Y., Kouhashi, K., Hayashida, M., Oda, Y., Ohga, S. & Taguchi, T., 5 1 2019, : : Pediatric surgery international. 35, 5, p. 551-557 7 p.

研究成果: ジャーナルへの寄稿記事

Hepatoblastoma
Indocyanine Green
Neoplasms
Liver
Lung
2 引用 (Scopus)

New Insights into Measles Virus Brain Infections

Watanabe, S., Shirogane, Y., Sato, Y., Hashiguchi, T. & Yanagi, Y., 2 1 2019, : : Trends in Microbiology. 27, 2, p. 164-175 12 p.

研究成果: ジャーナルへの寄稿評論記事

Measles virus
Virus Diseases
Brain
Subacute Sclerosing Panencephalitis
Viral Fusion Proteins
公開
Diabetes Mellitus
Insulin Resistance
Population
Homeostasis
Energy Intake

Periodontitis Is Associated with Chronic Obstructive Pulmonary Disease

Takeuchi, K., Matsumoto, K., Furuta, M., Fukuyama, S., Takeshita, T., Ogata, H., Suma, S., Shibata, Y., Shimazaki, Y., Hata, J., Ninomiya, T., Nakanishi, Y., Inoue, H. & Yamashita, Y., 5 1 2019, : : Journal of Dental Research. 98, 5, p. 534-540 7 p.

研究成果: ジャーナルへの寄稿記事

Periodontitis
Chronic Obstructive Pulmonary Disease
Vital Capacity
Forced Expiratory Volume
Confidence Intervals

Phenotypic characterization and virulence-related properties of Escherichia albertii strains isolated from children with diarrhea in Brazil

Lima, M. P., Yamamoto, D., de Mello Santos, A. C., Ooka, T., Hernandes, R. T., Vieira, M. A. M., Santos, F. F., Silva, R. M., Hayashi, T. & Gomes, T. A. T., 3 1 2019, : : Pathogens and disease. 77, 2

研究成果: ジャーナルへの寄稿記事

公開
Escherichia
Brazil
Virulence
Diarrhea
Virulence Factors
2 引用 (Scopus)

Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion

Matsuda, T., Irie, T., Katsurabayashi, S., Hayashi, Y., Nagai, T., Hamazaki, N., Adefuin, A. M. D., Miura, F., Ito, T., Kimura, H., Shirahige, K., Takeda, T., Iwasaki, K., Imamura, T. & Nakashima, K., 2 6 2019, : : Neuron. 101, 3, p. 472-485.e7

研究成果: ジャーナルへの寄稿記事

Microglia
Epigenomics
Neurons
Transcription Factors
Genes

Poor glycemic control and posterior circulation ischemic stroke

Fukuoka Stroke Registry Investigators, 4 1 2019, : : Neurology: Clinical Practice. 9, 2, p. 129-139 11 p.

研究成果: ジャーナルへの寄稿記事

Stroke
Propensity Score
Hemoglobins
Glucose
Insulin Resistance

Possibility of lung cancer risk in indium-exposed workers: An 11-year multicenter cohort study

Nakano, M., Omae, K., Tanaka, A. & Hirata, M., 5 1 2019, : : Journal of Occupational Health. 61, 3, p. 251-256 6 p.

研究成果: ジャーナルへの寄稿記事

公開
Indium
Multicenter Studies
Lung Neoplasms
Cohort Studies
Tomography

Prediction of liver fibrosis using CT under respiratory control: New attempt using deformation vectors obtained by non-rigid registration technique

Nishie, A., Akahori, S., Asayama, Y., Ishigami, K., ushijima, Y., Kakihara, D., Nakayama, T., Takayama, Y., Fujita, N., Morita, K., Ishimatsu, K., Takao, S., Yoshizumi, T., Kouhashi, K., Li, Y. & Honda, H., 3 1 2019, : : Anticancer research. 39, 3, p. 1417-1424 8 p.

研究成果: ジャーナルへの寄稿記事

Liver Cirrhosis
Fibrosis
Liver
ROC Curve
Area Under Curve

Predictive equation for post-mortem interval using spectrophotometric values of post-mortem lividity: A pilot study

Usumoto, Y., Kudo, K., Tsuji, A., Ihama, Y. & Ikeda, N., 4 1 2019, : : Forensic Science International. 297, p. 47-55 9 p.

研究成果: ジャーナルへの寄稿記事

Color
Skin Pigmentation
Skin
Femoral Vein
Cadaver

Predictive equation to estimate post-mortem interval using spectrophotometric blood-colour values

Usumoto, Y., Kudo, K., Tsuji, A., Ihama, Y. & Ikeda, N., 1 1 2019, : : Medicine, Science and the Law. 59, 1, p. 36-41 6 p.

研究成果: ジャーナルへの寄稿記事

Color
Values
Thigh
Cadaver
Autopsy