医学教育学部門

研究成果

1999

Ca2+ sensitization and potentiation of the maximum level of myofibrillar ATPase activity caused by mutations of troponin T found in familial hypertrophic cardiomyopathy

Yanaga, F., Morimoto, S. & Ohtsuki, I., 3 26 1999, : : Journal of Biological Chemistry. 274, 13, p. 8806-8812 7 p.

研究成果: ジャーナルへの寄稿記事

90 引用 (Scopus)

Central adrenomedullin augments the baroreceptor reflex in conscious rabbits

Matsumura, K., Abe, I., Tsuchihashi, T. & Fujishima, M., 4 1999, : : Hypertension. 33, 4, p. 992-997 6 p.

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

Differential effects of interleukin-4 and interleukin-10 on nitric oxide production by murine macrophages

Nemoto, Y., Otsuka, T., Niiro, H., Izuhara, K., Yamaoka, K., Nakashima, H. & Niho, Y., 12 1 1999, : : Inflammation Research. 48, 12, p. 643-650 8 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing

Shirane, M., Harumiya, Y., Ishida, N., Hirai, A., Miyamoto, C., Hatakeyama, S., Nakayama, K. I. & Kitagawa, M., 5 14 1999, : : Journal of Biological Chemistry. 274, 20, p. 13886-18893 5008 p.

研究成果: ジャーナルへの寄稿記事

210 引用 (Scopus)

Effects of chronic oral treatment with imidapril and TCV-116 on the responsiveness to angiotensin II in ventrolateral medulla of SHR

Tsuchihashi, T., Kagiyama, S., Matsumura, K., Abe, I. & Fujishima, M., 7 21 1999, : : Journal of hypertension. 17, 7, p. 917-922 6 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

Effects of interferon on circadian changes in blood pressure and heart rate variability in patients with chronic hepatitis

Fukuhara, M., Matsumura, K., Ohmori, S., Yanai, T., Tsubota, Y., Abe, I. & Fujishima, M., 5 1 1999, : : American Journal of Hypertension. 12, 5, p. 519-523 5 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

Effects of missense mutations Phe110Ile and Glu244Asp in human cardiac troponin T on force generation in skinned cardiac muscle fibers

Nakaura, H., Yanaga, F., Ohtsuki, I. & Morimoto, S., 1 1 1999, : : Journal of biochemistry. 126, 3, p. 457-460 4 p.

研究成果: ジャーナルへの寄稿記事

36 引用 (Scopus)

Expression of p53 and glutathione S-transferase-π relates to clinical drug resistance in non-small cell lung cancer

Nakanishi, Y., Kawasaki, M., Bai, F., Takayama, K., Pei, X. H., Takano, K., Inoue, K., Osaki, S. I., Hara, N. & Kiyohara, C., 11 1999, : : Oncology. 57, 4, p. 318-323 6 p.

研究成果: ジャーナルへの寄稿記事

36 引用 (Scopus)

Functional changes in troponin T by a splice donor site mutation that causes hypertrophic cardiomyopathy

Nakaura, H., Morimoto, S., Yanaga, F., Nakata, M., Nishi, H., Imaizumi, T. & Ohtsuki, I., 9 11 1999, : : American Journal of Physiology - Cell Physiology. 277, 2 46-2, p. C225-C232

研究成果: ジャーナルへの寄稿記事

42 引用 (Scopus)

Functional consequences of a carboxyl terminal missense mutation Arg278Cys in human cardiac troponin T

Morimoto, S., Nakaura, H., Yanaga, F. & Ohtsuki, I., 7 22 1999, : : Biochemical and Biophysical Research Communications. 261, 1, p. 79-82 4 p.

研究成果: ジャーナルへの寄稿記事

36 引用 (Scopus)

Hepatitis G virus infection in a high-risk subgroup of hospitalized dental patients

Takata, Y., Tateishi, A., Kurokawa, H., Fujikawa, M., Matsumura, K., Wakisaka, M., Fukuda, J. & Kajiyama, M., 1 1 1999, : : Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 87, 4, p. 442-445 4 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Inverse association between coffee drinking and serum uric acid concentrations in middle-aged Japanese males

Kiyohara, C., Kono, S., Honjo, S., Todoroki, I., Sakurai, Y., Nishiwaki, M., Hamada, H., Nishikawa, H., Koga, H., Ogawa, S. & Nakagawa, K., 9 2 1999, : : British Journal of Nutrition. 82, 2, p. 125-130 6 p.

研究成果: ジャーナルへの寄稿記事

67 引用 (Scopus)

Obesity, weight gain and risk of colon adenomas in Japanese men

Kono, S., Handa, K., Hayabuchi, H., Kiyohara, C., Inoue, H., Marugame, T., Shinomiya, S., Hamada, H., Onuma, K. & Koga, H., 8 1999, : : Japanese Journal of Cancer Research. 90, 8, p. 805-811 7 p.

研究成果: ジャーナルへの寄稿記事

97 引用 (Scopus)

Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus

Nakashima, H., Akahoshi, M., Tanaka, Y., Yamaoka, K., Ogami, E., Nagano, S., Arinobu, Y., Niiro, H., Otsuka, T. & Niho, Y., 11 1999, : : Rheumatology. 38, 11, p. 1142-1144 3 p.

研究成果: ジャーナルへの寄稿記事

16 引用 (Scopus)

Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells

Kamouchi, M., Philipp, S., Flockerzi, V., Wissenbach, U., Mamin, A., Raeymaekers, L., Eggermont, J., Droogmans, G. & Nilius, B., 7 15 1999, : : Journal of Physiology. 518, 2, p. 345-358 14 p.

研究成果: ジャーナルへの寄稿記事

150 引用 (Scopus)

Protective effects of hochu-ekki-to, a Chinese traditional herbal medicine against murine cytomegalovirus infection

Hossain, M. S., Takimoto, H., Hamano, S., Yoshida, H., Ninomiya, T., Minamishima, Y., Kimura, G. & Nomoto, K., 4 1 1999, : : Immunopharmacology. 41, 3, p. 169-181 13 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

Relationship between aromatic-DNA adduct levels and inducibility of the drug metabolizing enzyme aryl hydrocarbon hydroxylase in lymphocytes

Kiyohara, C., Ichiba, M., Zhang, J., Nakanishi, Y., Takayama, K., Hara, N. & Hirohata, T., 12 1 1999, : : Medical Science Research. 27, 10, p. 651-655 5 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Role of AT1 receptors in area postrema on baroreceptor reflex in spontaneously hypertensive rats

Matsumura, K., Averill, D. B. & Ferrario, C. M., 12 11 1999, : : Brain Research. 850, 1-2, p. 166-172 7 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Role of metabolic polymorphisms in lung carcinogenesis

Kiyohara, C. & Ohno, Y., 1 1 1999, : : [Nippon kōshū eisei zasshi] Japanese journal of public health. 46, 4, p. 241-249 9 p.

研究成果: ジャーナルへの寄稿評論記事

2 引用 (Scopus)

Selective DNA-binding activity of interleukin-10-stimulated STAT molecules in human monocytes

Yamaoka, K., Otsuka, T., Niiro, H., Nakashima, H., Tanaka, Y., Nagano, S., Ogami, E., Niho, Y., Hamasaki, N. & Izuhara, K., 7 27 1999, : : Journal of Interferon and Cytokine Research. 19, 6, p. 679-685 7 p.

研究成果: ジャーナルへの寄稿記事

16 引用 (Scopus)

Subtypes of metabotropic glutamate receptors in the nucleus of the solitary tract of rats

Matsumura, K., Tsuchihashi, T., Kagiyama, S., Abe, I. & Fujishima, M., 9 25 1999, : : Brain Research. 842, 2, p. 461-468 8 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)

Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus

Akahoshi, M., Nakashima, H., Tanaka, Y., Kohsaka, T., Nagano, S., Ohgami, E., Arinobu, Y., Yamaoka, K., Niiro, H., Shinozaki, M., Hirakata, H., Horiuchi, T., Otsuka, T. & Niho, Y., 8 1 1999, : : Arthritis and rheumatism. 42, 8, p. 1644-1648 5 p.

研究成果: ジャーナルへの寄稿記事

229 引用 (Scopus)

The combination of polymorphisms within interferon-γ receptor I and receptor 2 associated with the risk of systemic lupus erythematosus

Nakashima, H., Inoue, H., Akahoshi, M., Tanaka, Y., Yamaoka, K., Ogami, E., Nagano, S., Arinobu, Y., Niiro, H., Otsuka, T. & Niho, Y., 6 18 1999, : : FEBS Letters. 453, 1-2, p. 187-190 4 p.

研究成果: ジャーナルへの寄稿記事

53 引用 (Scopus)

Two polymorphisms within interleukin-3 (hlL3) gene detected by mismatch PCR/RFLP

Nakashima, H., Otsuka, T., Ohba, Y., Akahoshi, M., Nagano, S., Ogami, E., Arinobu, Y., Miyake, K., Inoue, Y., Niiro, H., Kaji, Y. & Niho, Y., 1 1 1999, : : Genes and Immunity. 1, 2, p. 156-158 3 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)
1998

Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene

Hamasaki, A., Sendo, F., Nakayama, K., Ishida, N., Negishi, I., Nakayama, K. I. & Hatakeyama, S., 12 7 1998, : : Journal of Experimental Medicine. 188, 11, p. 1985-1992 8 p.

研究成果: ジャーナルへの寄稿記事

177 引用 (Scopus)

Activation of STAT5 by lipopolysaccharide through granulocyte-macrophage colony-stimulating factor production in human monocytes

Yamaoka, K., Otsuka, T., Niiro, H., Arinobu, Y., Niho, Y., Hamasaki, N. & Izuhara, K., 1 15 1998, : : Journal of Immunology. 160, 2, p. 838-845 8 p.

研究成果: ジャーナルへの寄稿記事

48 引用 (Scopus)

Angiotensin II acts at AT1 receptors in the nucleus of the solitary tract to attenuate the baroreceptor reflex

Matsumura, K., Averill, D. B. & Ferrario, C. M., 11 1 1998, : : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 275, 5 44-5, p. R1611-R1619

研究成果: ジャーナルへの寄稿記事

96 引用 (Scopus)

Attenuation and recovery of brain stem autoregulation in spontaneously hypertensive rats

Toyoda, K., Fujii, K., Ibayashi, S., Kitazono, T., Nagao, T., Takaba, H. & Fujishima, M., 3 1998, : : Journal of Cerebral Blood Flow and Metabolism. 18, 3, p. 305-310 6 p.

研究成果: ジャーナルへの寄稿記事

16 引用 (Scopus)

Ca2+-sensitizing effects of the mutations at Ile-79 and Arg-92 of troponin T in hypertrophic cardiomyopathy

Morimoto, S., Yanaga, F., Minakami, R. & Ohtsuki, I., 7 1 1998, : : American Journal of Physiology - Cell Physiology. 275, 1 44-1, p. C200-C207

研究成果: ジャーナルへの寄稿記事

100 引用 (Scopus)

Central and peripheral mechanisms involved in hypertension induced by chronic inhibition of nitric oxide synthase in rats

Liu, Y., Tsuchihashi, T., Kagiyama, S., Matsumura, K., Abe, I. & Fujishima, M., 7 30 1998, : : Journal of hypertension. 16, 8, p. 1165-1173 9 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Central nitric oxide attenuates the baroreceptor reflex in conscious rabbits

Matsumura, K., Abe, I., Tsuchihashi, T. & Fujishima, M., 4 1 1998, : : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 274, 4 43-4, p. R1142-R1149

研究成果: ジャーナルへの寄稿記事

46 引用 (Scopus)

Cerebral blood flow and metabolism in patients with silent brain infarction: Occult misery perfusion in the cerebral cortex

Nakane, H., Ibayashi, S., Fujii, K., Sadoshima, S., Irie, K., Kitazono, T. & Fujishima, M., 9 1998, : : Journal of Neurology Neurosurgery and Psychiatry. 65, 3, p. 317-321 5 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

Changes in blood pressure and heart rate variability during dental surgery

Matsumura, K., Miura, K., Takata, Y., Kurokawa, H., Kajiyama, M., Abe, I. & Fujishima, M., 11 1 1998, : : American Journal of Hypertension. 11, 11 I, p. 1376-1380 5 p.

研究成果: ジャーナルへの寄稿記事

40 引用 (Scopus)

Effects of a long-acting angiotensin-converting enzyme inhibitor, imidapril, on the lower limit of cerebral blood flow autoregulation in hypertensive rats

Cai, H., Yao, H., Ibayashi, S., Zhao, G., Kitazono, T., Nagao, T. & Fujishima, M., 1 2 1998, : : European Journal of Pharmacology. 341, 1, p. 73-77 5 p.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

Effects of seasonal change on aryl hydrocarbon hydroxylase activity in human lymphocytes in a Japanese population

Kiyohara, C., Tanaka, K. & Hirohata, T., 3 21 1998, : : Medical Science Research. 26, 2, p. 75-78 4 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Immunohistochemically detected p53 and P-glycoprotein predict the response to chemotherapy in lung cancer

Kawasaki, M., Nakanishi, Y., Kuwano, K., Takayama, K., Kiyohara, C. & Hara, N., 8 1 1998, : : European Journal of Cancer. 34, 9, p. 1352-1357 6 p.

研究成果: ジャーナルへの寄稿記事

51 引用 (Scopus)

Interaction of opioids and vasopressin in central action of angiotensin II in conscious rabbits

Fukuhara, M., Matsumura, K., Abe, I. & Fujishima, M., 6 1 1998, : : Hypertension Research. 21, 2, p. 89-95 7 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

MAP kinase pathways as a route for regulatory mechanisms of IL-10 and IL-4 which inhibit COX-2 expression in human monocytes

Niiro, H., Otsuka, T., Ogami, E., Yamaoka, K., Nagano, S., Akahoshi, M., Nakashima, H., Arinobu, Y., Izuhara, K. & Niho, Y., 9 18 1998, : : Biochemical and Biophysical Research Communications. 250, 2, p. 200-205 6 p.

研究成果: ジャーナルへの寄稿記事

99 引用 (Scopus)

Methicillin-resistant Staphylococcus aureas (MRSA) and Pseudomonas aeruginosa isolation from pharyngeal swab cultures among the Japanese elderly at admission to a geriatric hospital

Washio, M., Kiyohara, C., Arai, Y., Aoyagi, K., Okada, K., Fujishima, M., Maeda, M. & Ito, Y., 1 1 1998, : : Public Health. 112, 6, p. 415-417 3 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Positive selection of extrathymically developed T cells by self-antigens

Yamada, H., Ninomiya, T., Hashimoto, A., Tamada, K., Takimoto, H. & Nomoto, K., 8 17 1998, : : Journal of Experimental Medicine. 188, 4, p. 779-784 6 p.

研究成果: ジャーナルへの寄稿記事

32 引用 (Scopus)

Protein kinase C modulates ischemia-induced amino acids release in the striatum of hypertensive rats

Nakane, H., Yao, H., Ibayashi, S., Kitazono, T., Ooboshi, H., Uchimura, H. & Fujishima, M., 1 26 1998, : : Brain Research. 782, 1-2, p. 290-296 7 p.

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)

Role of IL-10 in the crossregulation of prostaglandins and cytokines in monocytes

Niho, Y., Niiro, H., Tanaka, Y., Nakashima, H. & Otsuka, T., 4 18 1998, : : Acta Haematologica. 99, 3, p. 165-170 6 p.

研究成果: ジャーナルへの寄稿記事

40 引用 (Scopus)

Role of nitric oxide in the nucleus of the solitary tract of rats

Matsumura, K., Tsuchihashi, T., Kagiyama, S., Abe, I. & Fujishima, M., 7 6 1998, : : Brain Research. 798, 1-2, p. 232-238 7 p.

研究成果: ジャーナルへの寄稿記事

43 引用 (Scopus)

Role of tyrosine kinase in dilator responses of rat basilar artery in vivo

Kitazono, T., Ibayashi, S., Nagao, T., Fujii, K., Kagiyama, T. & Fujishima, M., 3 1998, : : Hypertension. 31, 3, p. 861-865 5 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

Role of tyrosine kinase in serotonin-induced constriction of the basilar artery in vivo

Kitazono, T., Ibayashi, S., Nagao, T., Kagiyama, T., Kitayama, J. & Fujishima, M., 2 1998, : : Stroke. 29, 2, p. 494-498 5 p.

研究成果: ジャーナルへの寄稿記事

19 引用 (Scopus)

Studies on the endothelin-1-induced contraction of rat granulation tissue pouch mediated by myofibroblasts

Goto, T., Yanaga, F. & Ohtsuki, I., 10 21 1998, : : Biochimica et Biophysica Acta - Molecular Cell Research. 1405, 1-3, p. 55-66 12 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

The relationship between CYP1A1 aryl hydrocarbon hydroxylase activity and lung cancer in a Japanese population

Kiyohara, C., Nakanishi, Y., Inutsuka, S., Takayama, K., Hara, N., Motohiro, A., Tanaka, K., Kono, S. & Hirohata, T., 8 24 1998, : : Pharmacogenetics. 8, 4, p. 315-323 9 p.

研究成果: ジャーナルへの寄稿記事

77 引用 (Scopus)
1997

Age-related changes in response of brain stem vessels to opening of ATP-sensitive potassium channels

Toyoda, K., Fujii, K., Takata, Y., Ibayashi, S., Kitazono, T., Nagao, T., Fujikawa, M. & Fujishima, M., 1 1997, : : Stroke. 28, 1, p. 171-175 5 p.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

An ATP-sensitive potassium channel activator reduces infarct volume in focal cerebral ischemia in rats

Takaba, H., Nagao, T., Yao, H., Kitazono, T., Ibayashi, S. & Fujishima, M., 10 18 1997, : : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 273, 2 42-2, p. R583-R586

研究成果: ジャーナルへの寄稿記事

29 引用 (Scopus)

Detection of polymorphisms within the human IL10 receptor cDNA gene sequence by RT-PCR RFLP

Tanaka, Y., Nakashima, H., Otsuka, T., Nemoto, Y., Niiro, H., Yamaoka, K., Ogami, E. I., Arinobu, Y., Tachida, H., Imamura, T. & Niho, Y., 9 25 1997, : : Immunogenetics. 46, 5, p. 439-441 3 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)