医学教育学部門

研究成果 1983 2019

2003
76 引用 (Scopus)

Dictyostelium differentiation-inducing factor-3 activates glycogen synthase kinase-3β and degrades cyclin D1 in mammalian cells

Takahashi, F., Taba, Y., Miwa, Y., Kubohara, Y., Watanabe, Y., Hirata, M., Morimoto, S. & Sasaguri, T., 3 14 2003, : : Journal of Biological Chemistry. 278, 11, p. 9663-9670 8 p.

研究成果: ジャーナルへの寄稿記事

Glycogen Synthase Kinase 3
Cyclin D1
Cells
Proteolysis
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone
164 引用 (Scopus)

Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death

Tsuruya, K., Ninomiya, T., Tokumoto, M., Hirakawa, M., Masutani, K., Taniguchi, M., Fukuda, K., Kanai, H., Kishihara, K., Hirakata, H. & Iida, M., 1 1 2003, : : Kidney International. 63, 1, p. 72-82 11 p.

研究成果: ジャーナルへの寄稿記事

Cisplatin
Cell Death
Kidney
Tumor Necrosis Factor Receptors
CD95 Antigens
46 引用 (Scopus)

Effects of carotid endarterectomy on cerebral blood flow and neuropsychological test performance in patients with high-grade carotid stenosis

Kishikawa, K., Kamouchi, M., Okada, Y., Inoue, T., Ibayashi, S. & Iida, M., 9 15 2003, : : Journal of the Neurological Sciences. 213, 1-2, p. 19-24 6 p.

研究成果: ジャーナルへの寄稿記事

Cerebrovascular Circulation
Carotid Endarterectomy
Neuropsychological Tests
Carotid Stenosis
Hematologic Tests
82 引用 (Scopus)

Estrogens Down-regulate p27Kip1 in Breast Cancer Cells through Skp2 and through Nuclear Export Mediated by the ERK Pathway

Foster, J. S., Fernando, R. I., Ishida, N., Nakayama, K. & Wimalasena, J., 10 17 2003, : : Journal of Biological Chemistry. 278, 42, p. 41355-41366 12 p.

研究成果: ジャーナルへの寄稿記事

Cell Nucleus Active Transport
Extracellular Signal-Regulated MAP Kinases
MCF-7 Cells
Estrogens
Estrogen Receptor Modulators
27 引用 (Scopus)

Genetic influences on smoking behavior and nicotine dependence: A review

Yoshimasu, K. & Kiyohara, C., 1 1 2003, : : Journal of epidemiology. 13, 4, p. 183-192 10 p.

研究成果: ジャーナルへの寄稿評論記事

Tobacco Use Disorder
Smoking
Mental Disorders
Genes
Schizophrenia
108 引用 (Scopus)

Interstitial pneumonia developed in a worker dealing with particles containing indium-tin oxide

Homma, T., Ueno, T., Sekizawa, K., Tanaka, A. & Hirata, M., 5 1 2003, : : Journal of Occupational Health. 45, 3, p. 137-139 3 p.

研究成果: ジャーナルへの寄稿記事

Tin Compounds
Indium
Metallurgy
indium tin oxide
75 引用 (Scopus)

Neural regulation of blood pressure by leptin and the related peptides

Matsumura, K., Tsuchihashi, T., Fujii, K. & Iida, M., 7 15 2003, : : Regulatory Peptides. 114, 2-3, p. 79-86 8 p.

研究成果: ジャーナルへの寄稿評論記事

Blood pressure
Leptin
Blood Pressure
Melanocyte-Stimulating Hormones
Peptides
2 引用 (Scopus)

Novel Nonsynonymous Polymorphisms of the CYP1AI Gene in Japanese

Saito, T., Egashira, M., Kiyotani, K., Fujieda, M., Yamazaki, H., Kiyohara, C., Kunitoh, H. & Kamataki, T., 2 1 2003, : : Drug Metabolism and Pharmacokinetics. 18, 3, p. 218-221 4 p.

研究成果: ジャーナルへの寄稿記事

Cytochrome P-450 CYP1A1
Single Nucleotide Polymorphism
Names
Genes
Nonsense Codon
40 引用 (Scopus)

Photothrombotic Middle Cerebral Artery Occlusion and Reperfusion Laser System in Spontaneously Hypertensive Rats

Yao, H., Sugimori, H., Fukuda, K., Takada, J., Ooboshi, H., Kitazono, T., Ibayashi, S. & Iida, M., 11 1 2003, : : Stroke. 34, 11, p. 2716-2721 6 p.

研究成果: ジャーナルへの寄稿記事

Middle Cerebral Artery Infarction
Inbred SHR Rats
Reperfusion
Cerebrovascular Circulation
Solid-State Lasers
13 引用 (Scopus)

Pulmonary Squamous Cyst Induced by Exposure to Indium Arsenide in Hamsters

Tanaka, A., Hirata, M. & Omura, M., 11 1 2003, : : Journal of Occupational Health. 45, 6, p. 405-407 3 p.

研究成果: ジャーナルへの寄稿記事

Arsenicals
Indium
Carcinogens
Animals
Semiconductor materials
41 引用 (Scopus)

Relation of plasma folate and methylenetetrahydrofolate reductase C677T polymorphism to colorectal adenomas

Marugame, T., Tsuji, E., Kiyohara, C., Eguchi, H., Oda, T., Shinchi, K. & Kono, S., 2 1 2003, : : International Journal of Epidemiology. 32, 1, p. 64-66 3 p.

研究成果: ジャーナルへの寄稿記事

Methylenetetrahydrofolate Reductase (NADPH2)
Folic Acid
Adenoma
Genotype
Odds Ratio
59 引用 (Scopus)

Risk modification by CYP1A1 and GSTM1 polymorphisms in the association of environmental tobacco smoke and lung cancer: A case-control study in Japanese nonsmoking women

Kiyohara, C., Wakai, K., Mikami, H., Sido, K., Ando, M. & Ohno, Y., 10 20 2003, : : International Journal of Cancer. 107, 1, p. 139-144 6 p.

研究成果: ジャーナルへの寄稿記事

Cytochromes
Smoke
Tobacco
Case-Control Studies
Lung Neoplasms
7 引用 (Scopus)

Systemic effects of orally administered p, p′-DDE on immature male Wistar rats during pubertal period

Makita, Y., Matsuura, T., Ogata, R., Romero, Y., Omura, M., Tanaka, A., Hirata, M. & Inoue, N., 7 1 2003, : : Journal of Occupational Health. 45, 4, p. 223-227 5 p.

研究成果: ジャーナルへの寄稿記事

Dichlorodiphenyl Dichloroethylene
Wistar Rats
Sexual Maturation
Sperm Count
Biochemistry

Systemic toxicity of p,p'-DDE in aged male Wistar rats following oral administration.

Makita, Y., Matsuura, T., Ogata, R., Omura, M., Tanaka, A., Hirata, M. & Inoue, N., 1 1 2003, : : Fukuoka igaku zasshi = Hukuoka acta medica. 94, 4, p. 59-65 7 p.

研究成果: ジャーナルへの寄稿記事

Dichlorodiphenyl Dichloroethylene
Oral Administration
Wistar Rats
Organ Size
Serum
10 引用 (Scopus)
Habits
Japan
Smoking
Students
Tobacco Products
15 引用 (Scopus)

Ultrasonographically predicting the extent of collateral flow through superficial temporal artery-to-middle cerebral artery anastomosis

Arakawa, S., Kamouchi, M., Okada, Y., Kishikawa, K., Omae, T., Inoue, T., Ibayashi, S. & Fujishima, M., 5 1 2003, : : American Journal of Neuroradiology. 24, 5, p. 886-891 6 p.

研究成果: ジャーナルへの寄稿記事

Temporal Arteries
Middle Cerebral Artery
Blood Flow Velocity
Therapeutic Occlusion
Ultrasonography
2 引用 (Scopus)

Ultrasonographic detection of extracranial vertebral artery compression in bow hunter's brain ischemia caused by neck rotation

Kamouchi, M., Kishikawa, K., matsuo, R., Yasumori, K., Inoue, T., Okada, Y. & Ibayashi, S., 8 11 2003, : : Cerebrovascular Diseases. 16, 3, p. 303-305 3 p.

研究成果: ジャーナルへの寄稿記事

Vertebrobasilar Insufficiency
Doppler Transcranial Ultrasonography
Doppler Color Ultrasonography
Cerebral Angiography
Vertebral Artery
2002

Caspase-3-mediated α-smooth muscle actin cleavage during staurosporine-induced myofibroblast apoptosis

Nakazono, A., Takahashi-Yanaga, F., Furue, M. & Sasaguri, T., 12 17 2002, : : Folia Pharmacologica Japonica. 120, SUPPL. 1

研究成果: ジャーナルへの寄稿記事

Staurosporine
Myofibroblasts
Caspase 3
Smooth Muscle
Actins
171 引用 (Scopus)

Central ghrelin modulates sympathetic activity in conscious rabbits

Matsumura, K., Tsuchihashi, T., Fujii, K., Abe, I. & Iida, M., 11 1 2002, : : Hypertension. 40, 5, p. 694-699 6 p.

研究成果: ジャーナルへの寄稿記事

Ghrelin
Rabbits
Arterial Pressure
Kidney
Heart Rate
42 引用 (Scopus)

Central α-melanocyte-stimulating hormone acts at melanocortin-4 receptor to activate sympathetic nervous system in conscious rabbits

Matsumura, K., Tsuchihashi, T., Abe, I. & Iida, M., 9 6 2002, : : Brain Research. 948, 1-2, p. 145-148 4 p.

研究成果: ジャーナルへの寄稿記事

Receptor, Melanocortin, Type 4
Melanocyte-Stimulating Hormones
Sympathetic Nervous System
Rabbits
Injections
6 引用 (Scopus)

Cerebral infarction due to carotid occlusion caused by cervical vagal neurilemmoma

matsuo, R., Kamouchi, M., Inoue, T., Okada, Y. & Ibayashi, S., 5 27 2002, : : Stroke. 33, 5, p. 1428-1431 4 p.

研究成果: ジャーナルへの寄稿記事

Neurilemmoma
Cerebral Infarction
Internal Carotid Artery
Neck
Neoplasms
13 引用 (Scopus)

Chronic administration of a tyrosine kinase inhibitor restores functional and morphological changes of the basilar artery during chronic hypertension

Kitayama, J., Kitazono, T., Ooboshi, H., Ago, T., Ohgami, T., Fujishima, M. & Ibayashi, S., 11 1 2002, : : Journal of Hypertension. 20, 11, p. 2205-2211 7 p.

研究成果: ジャーナルへの寄稿記事

Basilar Artery
Genistein
Protein-Tyrosine Kinases
Inbred WKY Rats
Hypertension
28 引用 (Scopus)

Chronic central infusion of orexin - A increases arterial pressure in rats

Lin, Y., Matsumura, K., Tsuchihashi, T., Abe, I. & Iida, M., 3 15 2002, : : Brain Research Bulletin. 57, 5, p. 619-622 4 p.

研究成果: ジャーナルへの寄稿記事

Arterial Pressure
Intraventricular Infusions
Blood Pressure
Drinking
Pentolinium Tartrate
7 引用 (Scopus)
Patient Readmission
Schizophrenia
Outpatients
Odds Ratio
Confidence Intervals

Ethical issues in cancer epidemiology and disease susceptibility genes

Washio, M., Kiyohara, C., Sugimori, H., Yamagata, Z. & Mori, M., 12 1 2002, : : Tumor Research. 37, p. 41-48 8 p.

研究成果: ジャーナルへの寄稿評論記事

Disease Susceptibility
Ethics
Epidemiology
Genes
Neoplasms
2 引用 (Scopus)

Gender difference in lung cancer susceptibility

Kiyohara, C., Yoshimasu, K. & Washio, M., 12 1 2002, : : Tumor Research. 37, p. 1-7 7 p.

研究成果: ジャーナルへの寄稿評論記事

Lung Neoplasms
Smoke
Tobacco Products
Cytochromes a1
Epidemiologic Studies
31 引用 (Scopus)

Genetic polymorphism of enzymes involved in xenobiotic metabolism and the risk of lung cancer

Kiyohara, C., Shirakawa, T. & Hopkin, J. M., 6 18 2002, : : Environmental health and preventive medicine. 7, 2, p. 47-59 13 p.

研究成果: ジャーナルへの寄稿評論記事

Xenobiotics
Genetic Polymorphisms
Lung Neoplasms
Enzymes
Cytochrome P-450 CYP2E1
125 引用 (Scopus)

Genetic polymorphisms and lung cancer susceptibility: A review

Kiyohara, C., Otsu, A., Shirakawa, T., Fukuda, S. & Hopkin, J. M., 9 1 2002, : : Lung Cancer. 37, 3, p. 241-256 16 p.

研究成果: ジャーナルへの寄稿評論記事

Genetic Polymorphisms
Lung Neoplasms
Genetic Predisposition to Disease
Carcinogens
Biomarkers
16 引用 (Scopus)

Genetic polymorphisms of cytochrome P450 1A1 and risk of gallbladder cancer

Tsuchiya, Y., Sato, T., Kiyohara, C., Yoshida, K., Ogoshi, K., Nakamura, K. & Yamamoto, M., 4 25 2002, : : Journal of Experimental and Clinical Cancer Research. 21, 1, p. 119-124 6 p.

研究成果: ジャーナルへの寄稿記事

Gallbladder Neoplasms
Genetic Polymorphisms
Cytochrome P-450 Enzyme System
isoleucylvaline
Cytochromes
22 引用 (Scopus)

Increased activity of calcium channels and Rho-associated kinase in the basilar artery during chronic hypertension in vivo

Kitazono, T., Ago, T., Kamouchi, M., Santa, N., Ooboshi, H., Fujishima, M. & Ibayashi, S., 5 1 2002, : : Journal of Hypertension. 20, 5, p. 879-884 6 p.

研究成果: ジャーナルへの寄稿記事

rho-Associated Kinases
Basilar Artery
Calcium Channels
Inbred WKY Rats
Inbred SHR Rats
16 引用 (Scopus)

Long-term effects of benidipine on cerebral vasoreactivity in hypertensive rats

Kitayama, J., Kitazono, T., Ooboshi, H., Takada, J., Fujishima, M. & Ibayashi, S., 3 8 2002, : : European Journal of Pharmacology. 438, 3, p. 153-158 6 p.

研究成果: ジャーナルへの寄稿記事

Inbred SHR Rats
Basilar Artery
Inbred WKY Rats
Nitroprusside
Acetylcholine
44 引用 (Scopus)

Molecular mechanisms of lipopolysaccharide-induced cyclooxygenase-2 expression in human neutrophils: Involvement of the mitogen-activated protein kinase pathway and regulation by anti-inflammatory cytokines

Nagano, S., Otsuka, T., Niiro, H., Yamaoka, K., Arinobu, Y., Ogami, E., Akahoshi, M., Inoue, Y., Miyake, K., Nakashima, H., Niho, Y. & Harada, M., 8 7 2002, : : International Immunology. 14, 7, p. 733-740 8 p.

研究成果: ジャーナルへの寄稿記事

Cyclooxygenase 2
Mitogen-Activated Protein Kinases
Lipopolysaccharides
Neutrophils
Anti-Inflammatory Agents
7 引用 (Scopus)

Myeloperoxidase-antineutrophil cytoplasmic antibody-associated glomerulonephritis superimposed on biopsy-proven diabetic nephrosclerosis.

Ninomiya, T., Kanai, H., Hirakawa, M., Arimura, Y., Masutani, K., Kashiwagi, M., Nakamura, S., Koga, Y., Fukuda, K. & Hirakata, H., 1 1 2002, : : American journal of kidney diseases : the official journal of the National Kidney Foundation. 39, 1

研究成果: ジャーナルへの寄稿記事

Nephrosclerosis
Antineutrophil Cytoplasmic Antibodies
Glomerulonephritis
Peroxidase
Kidney
228 引用 (Scopus)

Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

Ishida, N., Hara, T., Kamura, T., Yoshida, M., Nakayama, K. & Nakayama, K., 4 26 2002, : : Journal of Biological Chemistry. 277, 17, p. 14355-14358 4 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Cell Nucleus Active Transport
Serine
SKP Cullin F-Box Protein Ligases
Substitution reactions
38 引用 (Scopus)

Pulmonary toxicity of indium-tin oxide and indium phosphide after intratracheal instillations into the Lung of hamsters

Tanaka, A., Hirata, M., Omura, M., Inoue, N., Ueno, T., Homma, T. & Sekizawa, K., 5 13 2002, : : Journal of Occupational Health. 44, 2, p. 99-102 4 p.

研究成果: ジャーナルへの寄稿記事

Indium
Toxicity
indium phosphide
indium tin oxide
17 引用 (Scopus)

Role of CA 2+ -activated K + channels in the regulation of basilar arterial tone in spontaneously hypertensive rats

Kamouchi, M., Kitazono, T., Nagao, T., Fujishima, M. & Ibayashi, S., 6 26 2002, : : Clinical and Experimental Pharmacology and Physiology. 29, 7, p. 575-581 7 p.

研究成果: ジャーナルへの寄稿記事

Large-Conductance Calcium-Activated Potassium Channels
Basilar Artery
Inbred SHR Rats
Cerebral Arteries
Inbred WKY Rats

Safe endoscopic resection using a detachable snare: Large pedunculated Brunner's gland hyperplasia

Kubokawa, M., Hata, J., Ochiai, T., Araki, Y., Ito, K. I., Matsumoto, M., Hamada, S., Harada, N., Nishi, H., Tani, K. & Nawata, H., 10 10 2002, : : Digestive Endoscopy. 14, 3, p. 107-109 3 p.

研究成果: ジャーナルへの寄稿記事

Brunner Glands
Hyperplasia
Polyps
Hemorrhage
Endoscopy
12 引用 (Scopus)

Staurosporine-induced cleavage of α-smooth muscle actin during myofibroblast apoptosis

Nakazono-Kusaba, A., Takahashi, F., Morimoto, S., Furue, M. & Sasaguri, T., 1 1 2002, : : Journal of Investigative Dermatology. 119, 5, p. 1008-1013 6 p.

研究成果: ジャーナルへの寄稿記事

Staurosporine
Myofibroblasts
Smooth Muscle
Muscle
Actins
18 引用 (Scopus)

Testicular toxicity evaluation of indium-tin oxide

Omura, M., Tanaka, A., Hirata, M., Inoue, N., Ueno, T., Homma, T. & Sekizawa, K., 5 11 2002, : : Journal of Occupational Health. 44, 2, p. 105-107 3 p.

研究成果: ジャーナルへの寄稿記事

Indium
Toxicity
indium tin oxide
4 引用 (Scopus)
Antimony Potassium Tartrate
Antimony
Body Weight
Testis
Genitalia
2001
22 引用 (Scopus)

Adenovirus-mediated gene transfer to ischemic brain ischemic flow threshold for transgene expression

Ooboshi, H., Ibayashi, S., Takada, J., Yao, H., Kitazono, T. & Fujishima, M., 1 1 2001, : : Stroke. 32, 4, p. 1043-1047 5 p.

研究成果: ジャーナルへの寄稿記事

Cerebrovascular Circulation
Transgenes
Adenoviridae
Ischemia
Brain Ischemia
21 引用 (Scopus)

Apolipoprotein E genotype, serum lipids, and colorectal adenomas in Japanese men

Shinomiya, S., Sasaki, J., Kiyohara, C., Tsuji, E., Inoue, H., Marugame, T., Handa, K., Hayabuchi, H., Hamada, H., Eguchi, H., Fukushima, Y. & Kono, S., 3 10 2001, : : Cancer Letters. 164, 1, p. 33-40 8 p.

研究成果: ジャーナルへの寄稿記事

Apolipoproteins E
Adenoma
Genotype
Lipids
Serum
29 引用 (Scopus)

Association of body mass index with blood pressure in 80-year-old subjects

Matsumura, K., Ansai, T., Awano, S., Hamasaki, T., Akifusa, S., Takehara, T., Abe, I. & Takata, Y., 12 24 2001, : : Journal of Hypertension. 19, 12, p. 2165-2169 5 p.

研究成果: ジャーナルへの寄稿記事

Body Mass Index
Blood Pressure
Obesity
Hypertension
Creatinine
19 引用 (Scopus)

Bradykinin mediates, the acute effect of an angiotensin-converting enzyme inhibitor on cerebral autoregulation in rats

Takada, J., Ibayashi, S., Nagao, T., Ooboshi, H., Kitazono, T. & Fujishima, M., 1 1 2001, : : Stroke. 32, 5, p. 1216-1219 4 p.

研究成果: ジャーナルへの寄稿記事

Cerebrovascular Circulation
Bradykinin
Angiotensin-Converting Enzyme Inhibitors
Homeostasis
Captopril
32 引用 (Scopus)

Cardiovascular and sympathetic responses to dental surgery with local anesthesia

Nakamura, Y., Matsumura, K., Miura, K., Kurokawa, H., Abe, I. & Takata, Y., 7 7 2001, : : Hypertension Research. 24, 3, p. 209-214 6 p.

研究成果: ジャーナルへの寄稿記事

Local Anesthesia
Tooth
Blood Pressure
Tooth Extraction
Heart Rate
56 引用 (Scopus)

Central human cocaine- and amphetamine-regulated transcript peptide 55-102 increases arterial pressure in conscious rabbits

Matsumura, K., Tsuchihashi, T. & Abe, I., 1 1 2001, : : Hypertension. 38, 5, p. 1096-1100 5 p.

研究成果: ジャーナルへの寄稿記事

Amphetamine
Cocaine
Arterial Pressure
Rabbits
Injections
104 引用 (Scopus)

Central orexin-A augments sympathoadrenal outflow in conscious rabbits

Matsumura, K., Tsuchihashi, T. & Abe, I., 1 1 2001, : : Hypertension. 37, 6, p. 1382-1387 6 p.

研究成果: ジャーナルへの寄稿記事

Rabbits
Injections
Arterial Pressure
Kidney
Glucose
20 引用 (Scopus)

Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10

Maruyama, S. I., Hatakeyama, S., Nakayama, K., Ishida, N., Kawakami, K. & Nakayama, K., 9 15 2001, : : Genomics. 78, 3, p. 214-222 9 p.

研究成果: ジャーナルへの寄稿記事

Caenorhabditis elegans
F-Box Proteins
Presenilins
Genes
Proteins
48 引用 (Scopus)

Down-regulation of p27Kip1 expression is required for development and function of T cells

Tsukiyama, T., Ishida, N., Shirane, M., Minamishima, Y. A., Hatakeyama, S., Kitagawa, M., Nakayama, K. & Nakayama, K., 1 1 2001, : : Journal of Immunology. 166, 1, p. 304-312 9 p.

研究成果: ジャーナルへの寄稿記事

Down-Regulation
T-Lymphocytes
Thymocytes
Cell Lineage
Transgenic Mice
2 引用 (Scopus)

Effect of diet on changes in small intestinal blood flow following intracolonic administration of indomethacin to rats

Yamamoto, C., Kawakubo, K., Aoyagi, K., Matsumoto, T., Iida, M., Ibayashi, S., Kitazono, T., Doi, K., Kanamoto, K. & Fujishima, M., 3 28 2001, : : Digestive Diseases and Sciences. 46, 1, p. 200-207 8 p.

研究成果: ジャーナルへの寄稿記事

Indomethacin
Diet
Intestines
Fasting
Wistar Rats