医学教育学部門

研究成果 1983 2019

1993
11 引用 (Scopus)

A target K+ channel for the LP-805-induced hyperpolarization in smooth muscle cells of the rabbit portal vein

Kamouchi, M., Kajioka, S., Sakai, T., Kitamura, K. & Kuriyama, H., 1 1 1993, : : Naunyn-Schmiedeberg's Archives of Pharmacology. 347, 3, p. 329-335 7 p.

研究成果: ジャーナルへの寄稿記事

Portal Vein
Smooth Muscle Myocytes
Rabbits
Large-Conductance Calcium-Activated Potassium Channels
Charybdotoxin
7 引用 (Scopus)

Attenuation of nocturnal BP fall in essential hypertensives with cerebral infarction.

Matsumura, K., Abe, I., Fukuhara, M., Kobayashi, K., Sadoshima, S., Hasuo, K. & Fujishima, M., 6 1 1993, : : Journal of human hypertension. 7, 3, p. 309-310 2 p.

研究成果: ジャーナルへの寄稿レター

Cerebral Infarction
Circadian Rhythm
Blood Pressure
Hypertension
4 引用 (Scopus)

CIRCADIAN VARIATIONS OF BLOOD PRESSURE AND PULSE RATE IN ESSENTIAL HYPERTENSIVES WITH DIABETES MELLITUS

Matsumura, K., Abe, I., Tsuchihashi, T., Kobayashi, K. & Fujishima, M., 1 1 1993, : : Clinical and Experimental Pharmacology and Physiology. 20, 3, p. 155-160 6 p.

研究成果: ジャーナルへの寄稿記事

Diabetes Mellitus
Heart Rate
Blood Pressure
Orthostatic Hypotension
Circadian Rhythm
5 引用 (Scopus)

Invasive Development of Right Atrial Myxoma— A Case Report

Nakayama, M., Matsumura, K., Abe, I., Kaku, R., Kobayashi, K., Fujishima, M., Aso, H., Tokunaga, K. & Ishii, Y., 1 1 1993, : : Angiology. 44, 9, p. 739-744 6 p.

研究成果: ジャーナルへの寄稿記事

Myxoma
Heart Atria
Brachiocephalic Veins
Superior Vena Cava
Thrombosis
2 引用 (Scopus)

In vivo effect of 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity of mouse liver microsomes

Kiyohara, C. & Tomio, H., 1 1 1993, : : Toxicology Letters. 66, 2, p. 199-207 9 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
Methylcholanthrene
Liver Microsomes
Liver
Dichlorodiphenyldichloroethane
16 引用 (Scopus)

K channel openers activate different K channels in vascular smooth muscle cells

Kitamura, K. & Kamouchi, M., 8 1 1993, : : Cardiovascular Drugs and Therapy. 7, 3 Supplement, p. 539-546 8 p.

研究成果: ジャーナルへの寄稿記事

Portal Vein
Vascular Smooth Muscle
Smooth Muscle Myocytes
Rabbits
Glyburide

Methyl alcohol poisoning

Inoue, N., Omura, M. & Hirata, M., 1 1 1993, : : Fukuoka igaku zasshi = Hukuoka acta medica. 84, 2, p. 37-42 6 p.

研究成果: ジャーナルへの寄稿評論記事

X Ray Computed Tomography
Hematologic Tests
Poisoning
Methanol
Central Nervous System
2 引用 (Scopus)

Synergism between muramyl dipeptide and lipopolysaccharide in the inhibition of glycosaminoglycan synthesis in cultured rat costal chondrocytes

Ikebe, T., Hirata, M., Takahashi, F. & Koga, T., 1 1 1993, : : Annals of the Rheumatic Diseases. 52, 1, p. 32-36 5 p.

研究成果: ジャーナルへの寄稿記事

Acetylmuramyl-Alanyl-Isoglutamine
Chondrocytes
Glycosaminoglycans
Lipopolysaccharides
Rats
3 引用 (Scopus)

The acute toxicity of allyl chloride by subcutaneous injection in mice.

Omura, M., Itonaga, Y., Komatsu, H., Mangen, Z., Hirata, M., Tanaka, A. & Inoue, N., 1 1 1993, : : Fukuoka igaku zasshi = Hukuoka acta medica. 84, 10, p. 427-432 6 p.

研究成果: ジャーナルへの寄稿記事

Leydig Cells
Subcutaneous Injections
Necrosis
Kidney Tubules
Inbred ICR Mouse
6 引用 (Scopus)

Transfection of interferon-γ gene in a mouse bone marrow stromal preadipocyte cell line causes apoptotic cell death

Nakano, T., Otsuka, T., Ogo, T., Niiro, H., Kuga, S., Zipori, D., Furukawa, Y. & Niho, Y., 12 1 1993, : : Experimental Hematology. 21, 11, p. 1498-1503 6 p.

研究成果: ジャーナルへの寄稿記事

Mesenchymal Stromal Cells
Interferons
Transfection
Cell Death
Cell Line
1992
7 引用 (Scopus)

Activation of cultured bovine aortic endothelial cells by extracellular pyrimidine triphosphate

Kitazono, T., Koichiro, T. & Shigeki, M., 1 1 1992, : : International Journal of Biochemistry. 24, 8, p. 1323-1327 5 p.

研究成果: ジャーナルへの寄稿記事

Endothelial cells
Endothelial Cells
Uridine Triphosphate
Adenosine Triphosphate
Chemical activation

Central effect of μ and δ opioids on neurohormonal and baroreflex regulation in conscious rabbits

Matsumura, K., Abe, I., Tsuchihashi, T., Tominaga, M., Kobayashi, K. & Fujishima, M., 1 1 1992, : : Therapeutic Research. 13, 1, p. 212-217 6 p.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Opioid Analgesics
Rabbits
1 引用 (Scopus)

Comparison of suppression of mutagenicity of benzo(a)pyrene among methylsulfonyl polychlorinated biphenyl isomers

Kiyohara, C., Omura, M., Hirohata, T. & Masuda, Y., 6 1 1992, : : Bulletin of Environmental Contamination and Toxicology. 48, 6, p. 877-883 7 p.

研究成果: ジャーナルへの寄稿記事

Benzoflavones
Mutagenicity Tests
Aryl Hydrocarbon Hydroxylases
Benzo(a)pyrene
mutagenicity
16 引用 (Scopus)

Differential modulation by μ- and θ-opioids on baroreceptor reflex in conscious rabbits

Matsumura, K., Abe, I., Tominaga, M., Tsuchihashi, T., Kobayashi, K. & Fujishima, M., 1 1 1992, : : Hypertension. 19, 6, p. 648-652 5 p.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Opioid Analgesics
Enkephalins
Rabbits
Naloxone
37 引用 (Scopus)

Epstein-Barr virus BCRF1 gene product (viral interleukin 10) inhibits superoxide anion production by human monocytes

Niiro, H., Otsuka, T., Abe, M., Satoh, H., Ogo, T., Nakano, T., Furukawa, Y. & Niho, Y., 1 1 1992, : : Lymphokine and Cytokine Research. 11, 5, p. 209-214 6 p.

研究成果: ジャーナルへの寄稿記事

Viral Proteins
Human Herpesvirus 4
Superoxides
Interleukin-10
Monocytes

In vitro/in vivo effects of 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity of mice.

Kiyohara, C. & Hirohata, T., 1 1 1992, : : Veterinary and human toxicology. 34, 5, p. 413-416 4 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
unspecific monooxygenase
tetrachlorodibenzo-p-dioxin
Methylcholanthrene
mice

Ion transport system in the smooth muscle and hypertension

Suzuki, S., Kamouchi, M. & Kuriyama, H., 1 1 1992, : : Nippon rinsho. Japanese journal of clinical medicine. 50 Suppl, p. 422-429 8 p.

研究成果: ジャーナルへの寄稿評論記事

Active Biological Transport
Ion Transport
Calcium Channels
Vascular Smooth Muscle
Smooth Muscle
38 引用 (Scopus)

Signal transduction by tumor necrosis factor α is mediated through a guanine nucleotide-binding protein in osteoblast-like cell line, MC3T3-E1

Yanaga, F., Abe, M., Koga, T. & Hirata, M., 1 1 1992, : : Journal of Biological Chemistry. 267, 8, p. 5114-5121 8 p.

研究成果: ジャーナルへの寄稿記事

Signal transduction
Guanine Nucleotides
Osteoblasts
Signal Transduction
Carrier Proteins
54 引用 (Scopus)

Tumor necrosis factor α stimulates sphingomyelinase through the 55 kDa receptor in HL-60 cells

Takahashi, F. & Watson, S. P., 12 21 1992, : : FEBS Letters. 314, 3, p. 297-300 4 p.

研究成果: ジャーナルへの寄稿記事

Sphingomyelin Phosphodiesterase
HL-60 Cells
Sphingomyelins
Hydrolysis
Tumor Necrosis Factor-alpha
1991
4 引用 (Scopus)

Ambulatory blood pressure monitoring in elderly hypertensives treated with the new calcium antagonist, nilvadipine

Tsuchihashi, T., Tsukashima, A., Matsumura, K., Abe, I., Tominaga, M., Nakao, Y., Kobayashi, K. & Fujishima, M., 9 1 1991, : : European Journal of Clinical Pharmacology. 41, 3, p. 255-257 3 p.

研究成果: ジャーナルへの寄稿記事

nilvadipine
Ambulatory Blood Pressure Monitoring
Calcium
Blood Pressure
Heart Rate
5 引用 (Scopus)
4-Nitroquinoline-1-oxide
Xeroderma Pigmentosum
Cell Line
Survival
Homozygote
1 引用 (Scopus)

Cellular and subcellular clues to hypertension: Assessment from calcium mobilization data

Kamouchi, M., Akata, T., Xiong, Z., Inoue, R., Kitamura, K. & Kuriyama, H., 12 1 1991, : : Journal of Vascular Medicine and Biology. 3, 4, p. 205-218 14 p.

研究成果: ジャーナルへの寄稿記事

Hypertension
Calcium
49 引用 (Scopus)

Central effect of endothelin on neurohormonal responses in conscious rabbits

Matsumura, K., Abe, I., Tsuchihashi, T., Tominaga, M., Kobayashi, K. & Fujishima, M., 1 1 1991, : : Hypertension. 17, 6 SUPPL. 2, p. 1192-1196 5 p.

研究成果: ジャーナルへの寄稿記事

Endothelins
Endothelin-1
Rabbits
Kidney
Pentolinium Tartrate
31 引用 (Scopus)

Cromakalim dilates rat cerebral arteries in vitro

Nagao, T., Sadoshima, S., Kamouchi, M. & Fujishima, M., 1 1 1991, : : Stroke. 22, 2, p. 221-224 4 p.

研究成果: ジャーナルへの寄稿記事

Cromakalim
Cerebral Arteries
Arteries
Perfusion
Pressure
1 引用 (Scopus)

Disseminated intravascular coagulation in a patient with progressive systemic sclerosis associated with necrotizing angiitis and generalized lymphadenopathy

Kamouchi, M., Yoshinari, M., Goto, H., Ishitsuka, T., Murai, K., Tashiroh, K. & Fujishima, M., 1 1 1991, : : Acta Haematologica. 86, 4, p. 203-205 3 p.

研究成果: ジャーナルへの寄稿記事

Diffuse Scleroderma
Disseminated Intravascular Coagulation
Vasculitis
Lymphadenopathy
3 引用 (Scopus)

Distribution of sensitivity to 4-nitroquinoline 1-oxide among Japanese lymphoblastoid cell lines

Kiyohara, C., Hirohata, T., Kuratsune, M. & Nagayama, J., 1 1 1991, : : Bulletin of Environmental Contamination and Toxicology. 46, 1, p. 62-68 7 p.

研究成果: ジャーナルへの寄稿記事

Fluoresceins
4-Nitroquinoline-1-oxide
Cultured Tumor Cells
Xeroderma Pigmentosum
Preschool Children

Electrical properties of the voltage-dependent calcium channels in smooth muscle cells

Kitamura, K., Xiong, Z. L. & Kamouchi, M., 1 1 1991, : : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 36, 6, p. 869-879 11 p.

研究成果: ジャーナルへの寄稿記事

Electric Conductivity
Endothelins
Second Messenger Systems
Calcium Channels
Muscle Contraction
37 引用 (Scopus)

Evidence for coupling of bradykinin receptors to a guanine-nucleotide binding protein to stimulate arachidonate liberation in the osteoblast-like cell line, MC3T3-E1

Takahashi, F., Hirata, M. & Toshitaka, K., 9 3 1991, : : BBA - Molecular Cell Research. 1094, 2, p. 139-146 8 p.

研究成果: ジャーナルへの寄稿記事

Bradykinin Receptors
Guanine Nucleotides
Bradykinin
Osteoblasts
Radioactivity

Interrelationship of cellular fluorescein formation ability, an indication of cell viability, with environmental factors and with aryl hydrocarbon hydroxylase activity

Kiyohara, C., Hirohata, T., Kuratsune, M. & Nagayama, J., 1 1 1991, : : Chemosphere. 22, 8, p. 739-746 8 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
Fluorescein
Cell Survival
viability
environmental factor
5 引用 (Scopus)
Aryl Hydrocarbon Hydroxylases
Microsomes
Ascorbic Acid
Liver
Aromatic Hydrocarbons
7 引用 (Scopus)
Bradycardia
Portal Vein
Smooth Muscle Myocytes
Rabbits
Glyburide
3 引用 (Scopus)

Severe Hypertension with Segmental Renal Infarction Following Surgical Removal of a Retroperitoneal Malignant Hemangiopericytoma: A Case Report

Matsumura, K., Muratani, H., Kinjou, K., Kimura, Y., Eto, T., Fukiyama, K. & Kusaba, A., 1 1 1991, : : Angiology. 42, 4, p. 331-336 6 p.

研究成果: ジャーナルへの寄稿記事

Infarction
Renin-Angiotensin System
Hypertension
Kidney
Angiotensins
4 引用 (Scopus)

Synthetic inositol 1,3,4,5-tetrakisphosphate analogues

Hirata, M., Kimura, Y., Ishimatsu, T., Takahashi, F., Shuto, T., Sasaguri, T., Koga, T., Watanabe, Y. & Ozaki, S., 1 1 1991, : : Biochemical Journal. 276, 2, p. 333-336 4 p.

研究成果: ジャーナルへの寄稿記事

Phosphoric Monoester Hydrolases
Inositol 1,4,5-Trisphosphate
inositol-1,3,4,5-tetrakisphosphate
Erythrocyte Membrane
Hydrolysis
11 引用 (Scopus)

Tubulointerstitial disorders in the kidney associated with primary biliary cirrhosis (PBC) [2]

Kamouchi, M., Tsuji, H., Hirakata, H., Okamura, K., Ishitsuka, T., Murai, K., Onoyama, K. & Fujishima, M., 1 1 1991, : : Clinical Nephrology. 35, 3, p. 134-135 2 p.

研究成果: ジャーナルへの寄稿レター

Thyroiditis
Interstitial Nephritis
Biliary Liver Cirrhosis
Sjogren's Syndrome
Prednisolone
1990
4 引用 (Scopus)

Aryl hydrocarbon hydroxylase activity levels in the hepatic microsomal fraction from MC- or TCDD-treated mice: a comparison between aromatic hydrocarbon responsive and non-responsive strains

Kiyohara, C., Mohri, N., Hirohata, T., Haraguchi, K., Masuda, Y. & Nagayama, J., 1 1 1990, : : Toxicology Letters. 52, 1, p. 73-80 8 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
Aromatic Hydrocarbons
Liver
Methylcholanthrene
Polycyclic Aromatic Hydrocarbons
11 引用 (Scopus)

Baroreceptor reflex in elderly essential hypertensives: Effect of chronic inhibition of angiotensin converting enzyme

Muratani, H., Kimura, Y., Matsumura, K., Noda, Y., Eto, T. & Fukiyama, K., 1 1 1990, : : Clinical and Experimental Hypertension. A12, 1, p. 97-110 14 p.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Peptidyl-Dipeptidase A
Angiotensin II
Enalapril
Blood Pressure
2 引用 (Scopus)

Catabolic effects of muramyl dipeptide on rabbit chondrocytes

Ikebe, T., Iribe, H., Hirata, M., Yanaga, F. & Koga, T., 1990, : : Arthritis and Rheumatism. 33, 12, p. 1801-1806 6 p.

研究成果: ジャーナルへの寄稿記事

Acetylmuramyl-Alanyl-Isoglutamine
Proteoglycans
Chondrocytes
Glycosaminoglycans
Rabbits
4 引用 (Scopus)
Tumors
Toxicity
gallium oxide
gallium arsenide
gallium phosphide
2 引用 (Scopus)

Comparative toxicologic study of 2,3,4,7,8-pentachlorodibenzofuran in Ah responsive and nonresponsive strains of mice

Nagayama, J., Kiyohara, C., Handa, S. & Horie, A., 1 1 1990, : : Chemosphere. 20, 7-9, p. 1165-1172 8 p.

研究成果: ジャーナルへの寄稿記事

comparative study
toxicity
Liver
genotype
Toxicity
6 引用 (Scopus)

Effects of 3-methylsulphonyl-4,5,3′,4′-tetrachlorobiphenyl and 7,8-benzoflavone on mouse liver aryl hydrocarbon hydroxylase activity in vitro

Kiyohara, C., Hirohata, T., Mohri, N. & Masuda, Y., 1 1 1990, : : Toxicology in Vitro. 4, 2, p. 103-107 5 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
Liver
Atrial Natriuretic Factor
Methylcholanthrene
Aromatic Hydrocarbons
50 引用 (Scopus)

Effects of glutathione depletion on the acute nephrotoxic potential of arsenite and on arsenic metabolism in hamsters

Hirata, M., Tanaka, A., Hisanaga, A. & Ishinishi, N., 1 1 1990, : : Toxicology and Applied Pharmacology. 106, 3, p. 469-481 13 p.

研究成果: ジャーナルへの寄稿記事

Buthionine Sulfoximine
Arsenic
Metabolism
Cricetinae
Glutathione
50 引用 (Scopus)

Inositol 1,4,5-trisphosphate affinity chromatography

Hirata, M., Watanabe, Y., Ishimatsu, T., Takahashi, F., Koga, T. & Ozaki, S., 4 16 1990, : : Biochemical and Biophysical Research Communications. 168, 1, p. 379-386 8 p.

研究成果: ジャーナルへの寄稿記事

Affinity chromatography
Inositol 1,4,5-Trisphosphate
Affinity Chromatography
Sepharose
Bioactivity
21 引用 (Scopus)

In Vitro Effects of Methylsulfonyl Polychlorinated Biphenyls and 7,8‐Benzoflavone on Aryl Hydrocarbon Hydroxylase Activity in Human Lymphoblastoid Cells

Kiyohara, C., Mohri, N., Hirohata, T., Haraguchi, K. & Masuda, Y., 1 1 1990, : : Pharmacology & Toxicology. 66, 4, p. 273-276 4 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
Polychlorinated Biphenyls
Human Activities
Isomers
Culture Media
1 引用 (Scopus)

Opioids modulate cardiovascular and neurohormonal responses to intracerebroventricular injection of endothelin in conscious rabbits

Matsumura, K., Abe, I., Tsuchihashi, T., Tominaga, M., Kobayashi, K. & Fujishima, M., 12 1 1990, : : Therapeutic Research. 11, 12, p. 105-110 6 p.

研究成果: ジャーナルへの寄稿記事

Endothelins
Opioid Analgesics
Rabbits
Injections
54 引用 (Scopus)

Stereospecific recognition of inositol 1,4,5-trisphosphate analogs by the phosphatase, kinase, and binding proteins

Hirata, M., Yanaga, F., Koga, T., Ogasawara, T., Watanabe, Y. & Ozaki, S., 5 25 1990, : : Journal of Biological Chemistry. 265, 15, p. 8404-8407 4 p.

研究成果: ジャーナルへの寄稿記事

Inositol 1,4,5-Trisphosphate
Phosphoric Monoester Hydrolases
Isomers
Carrier Proteins
Phosphotransferases
1989
6 引用 (Scopus)

Comparative toxicologic study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in Ah responsive and nonresponsive strains of mice

Nagayama, J., Mohri, N., Kiyohara, C., Handa, S. & Horie, A., 1 1 1989, : : Chemosphere. 19, 1-6, p. 927-932 6 p.

研究成果: ジャーナルへの寄稿記事

TCDD
dioxin
Toxicity
comparative study
toxicity
22 引用 (Scopus)

Conversion of arsenite and arsenate to methylarsenic and dimethylarsenic compounds by homogenates prepared from livers and kidneys of rats and mice

Hirata, M., Mohri, T., Hisanaga, A. & Ishinishi, N., 1 1 1989, : : Applied Organometallic Chemistry. 3, 4, p. 335-341 7 p.

研究成果: ジャーナルへの寄稿記事

Liver
Rats
Arsenic
Methylation
Mercaptoethanol
1 引用 (Scopus)

Effects of 3-methylsulphonyl-4,5,3',4'-tetrachlorobiphenyl and 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity

Nagayama, J., Mohri, N., Haraguschi, K., Masuda, Y., Kiyohara, C. & Hirohata, T., 1 1 1989, : : Fukuoka Acta Medica. 80, 5, p. 201-209 9 p.

研究成果: ジャーナルへの寄稿記事

Benzoflavones
Aryl Hydrocarbon Hydroxylases
Flavones
Polychlorinated Biphenyls
Liver Microsomes

Effects of dioxin congeners on aryl hydrocarbon hydroxylase activity

Nagayama, J., Mohri, N., Masuda, Y., Kiyohara, C. & Hirohata, T., 1 1 1989, : : Fukuoka Acta Medica. 80, 5, p. 196-200 5 p.

研究成果: ジャーナルへの寄稿記事

Drug Dose Response Relationship
Aryl Hydrocarbon Hydroxylases
Dioxins
Cultured Cells
Lymphocytes
8 引用 (Scopus)

Inhibitory effect of methylsulphonyl polychlorinated biphenyls on aryl hydrocarbon hydroxylase activity

Nagayama, J., Kiyohara, C., Mohri, N., Hirohata, T., Haraguchi, K. & Masuda, Y., 1 1 1989, : : Chemosphere. 18, 1-6, p. 701-708 8 p.

研究成果: ジャーナルへの寄稿記事

PCB
hydrocarbon
effect